Mc1r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mc1r
melanocortin 1 receptor
MGI:99456

20 phenotypes from 10 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mc1r^e-J/Mc1r^e-J B6.C-H2-Ab1^bm12/KhEg-Mc1r^e-J/J	abnormal pain threshold	J:105413
	normal pigmentation phenotype	J:141035
	yellow coat color	J:141035
Mc1r^E-so3J/Mc1r⁺ involves: CBA/J	abnormal pinna hair pigmentation	J:78801
Mc1r^E-so3J/Mc1r^E-so3J involves: CBA/J	darkened coat color	J:78801
Mc1r^E-So4J/Mc1r⁺ B6.Cg-Mc1r^E-So4J/GrsrJ	abnormal pinna hair pigmentation	J:230486
	abnormal tail hair pigmentation	J:230486
	darkened coat color	J:230486
Mc1r^E-so/Mc1r⁺ involves: C3H	abnormal skin pigmentation	J:13077
	darkened coat color	J:13077
	hyperpigmentation	J:13077
Mc1r^E-so/Mc1r^E-so involves: C3H	abnormal skin pigmentation	J:13077
	darkened coat color	J:13077
	hyperpigmentation	J:13077
Mc1r^e/Mc1r^e C57BL/6J-Mc1r^e/J	abnormal keratinocyte apoptosis	J:112959
	abnormal melanogenesis	J:112959
	abnormal skin pigmentation	J:112959
	increased cellular sensitivity to ionizing radiation	J:112959
Mc1r^e/Mc1r^e involves: C57BL/6	abnormal pain threshold	J:112815
	abnormal touch/ nociception	J:112815
	analgesia	J:112815
Mc1r^e/Mc1r^e involves: C57BL/6Ha	abnormal hair follicle melanogenesis	J:5563
	abnormal hair follicle pheomelanosome pheomelanin content	J:129904
	yellow coat color	J:5110, J:5620, J:129904
Mc1r^m1Btlr/Mc1r^m1Btlr C57BL/6J-Mc1r^m1Btlr	abnormal coat/hair pigmentation	J:173673
Mc1r^mpc59H/Mc1r^mpc59H involves: BALB/c * C3H/HeH * C57BL/6J	yellow coat color	J:234901
Mc1r^taw/Mc1r^e involves: M. m. molossinus * C57BL/6J	yellow coat color	J:55617
Mc1r^taw/Mc1r^taw M. m. molossinus	abnormal coat/hair pigmentation	J:98397
	abnormal skin pigmentation	J:98397
	decreased ear pigmentation	J:98397
	decreased tail pigmentation	J:98397
	yellow coat color	J:98397
Mc1r^{tm1.1(KOMP)Vlcg}/Mc1r^{tm1.1(KOMP)Vlcg} C57BL/6N-Mc1r^{tm1.1(KOMP)Vlcg}/Ucd	abnormal coat/hair pigmentation	J:211773
	abnormal skin morphology	J:211773
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(CMV-cre)1Cgn/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac	yellow coat color	J:231435
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(CMV-cre)1Cgn/0 Tg(Dct-lacZ)#Ove/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB/N	abnormal epidermal melanocyte morphology	J:231435
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(Dct-lacZ)#Ove/0 Tg(Krt1-15-cre/PGR)22Cot/0 involves: 129S6/SvEvTac C57BL/6J * C57BL/6NTac * FVB/N * SJL/J	normal pigmentation phenotype	J:231435
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(Dct-lacZ)#Ove/0 Tg(Tyr-cre/ERT2)13Bos/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB/N	abnormal epidermal melanocyte morphology	J:231435
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(Krt1-15-cre/PGR)22Cot/0 involves: 129S6/SvEvTac C57BL/6J * C57BL/6NTac * SJL/J	normal pigmentation phenotype	J:231435
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(Tyr-cre/ERT2)13Bos/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac	yellow coat color	J:231435

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