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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Xbp1
X-box binding protein 1
MGI:98970
34 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atg7tm1Tchi/Atg7tm1Tchi
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Defa6-icre)1Rsb/0
involves: 129S6/SvEvTac * C57BL/6 * CBA 		small intestinal inflammation J:206084
Atg7tm1Tchi/Atg7tm1Tchi
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL 		abnormal autophagy J:206084
abnormal enterocyte physiology J:206084
ileum inflammation J:206084
intestinal inflammation J:206084
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Tg(Vil1-cre)997Gum/0
Xbp1tm2Glm/Xbp1tm2Glm
B6.Cg-Atg16l1tm1Kuv Xbp1tm2Glm Tg(Vil1-cre)997Gum 		increased enterocyte apoptosis J:269933
small intestinal inflammation J:269933
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal enterocyte physiology J:206084
ileum inflammation J:206084
intestinal inflammation J:206084
Cadtm1c(KOMP)Wtsi/Cadtm1c(KOMP)Wtsi
Tg(Adipoq-rtTA)2Zvw/0
Tg(tetO-cre)1Jaw/0
Tg(tetO-Xbp1_is)#Pesch/0
involves: 129 * C57BL/6 * C57BL/6N * FVB/N 		normal adipose tissue phenotype J:260830
normal homeostasis/metabolism phenotype J:260830
weight loss J:260830
Ern1tm2.1Tiw/Ern1tm2.1Tiw
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * SJL 		small intestinal inflammation J:206084
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Tg(tetO-Xbp1_is)#Pesch/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA * FVB 		abnormal glucose homeostasis J:194290
abnormal liver morphology J:194290
decreased circulating insulin level J:194290
decreased fasting circulating glucose level J:194290
decreased liver glycogen level J:194290
decreased total body fat amount J:194290
enhanced lipolysis J:194290
hepatic steatosis J:194290
hypoglycemia J:194290
increased circulating free fatty acids level J:194290
increased insulin sensitivity J:194290
increased liver triglyceride level J:194290
increased respiratory quotient J:194290
Lepob/Lepob
Tg(tetO-Xbp1_is)#Pesch/0
Tg(Adipoq-rtTA)2Zvw/0
involves: C57BL/6 * C57BL/6N * FVB/N 		decreased susceptibility to diet-induced obesity J:260830
Tg(tetO-Xbp1_is)#Pesch/0
Tg(Adipoq-rtTA)2Zvw/0
involves: C57BL/6 * C57BL/6N * FVB/N 		abnormal nucleotide metabolism J:260830
abnormal white adipose tissue morphology J:260830
decreased body fat mass J:260830
decreased body temperature J:260830
decreased brown adipose tissue mass J:260830
decreased fat cell size J:260830
decreased susceptibility to diet-induced obesity J:260830
decreased white adipose tissue mass J:260830
increased basal metabolism J:260830
increased carbon dioxide production J:260830
increased fatty acid oxidation J:260830
increased oxygen consumption J:260830
weight loss J:260830
Xbp1tm2Glm/Xbp1tm2Glm
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tg(Vil1-cre)997Gum/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		small intestinal inflammation J:206084
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory