Vwf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vwf
Von Willebrand factor
MGI:98941

22 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vwf^tm1.1Diac/Vwf^tm1.1Diac Not Specified	abnormal platelet activation	J:181672
	impaired blood coagulation	J:220792
	increased bleeding time	J:181672, J:220792
Vwf^tm1.1Geno/Vwf⁺ involves: C57BL/6	abnormal platelet aggregation	J:250145
	abnormal platelet physiology	J:250145
	abnormal response to injury	J:250145
	decreased platelet aggregation	J:250145
	increased acute inflammation	J:250145
	increased bleeding time	J:250145
	increased hemoglobin content	J:250145
	increased mean platelet volume	J:250145
	thrombocytopenia	J:250145
Vwf^tm1.1Geno/Vwf^tm1.1Geno involves: C57BL/6	abnormal platelet aggregation	J:250145
	abnormal platelet physiology	J:250145
	abnormal response to injury	J:250145
	decreased platelet aggregation	J:250145
	decreased susceptibility to induced thrombosis	J:250145
	increased acute inflammation	J:250145
	increased bleeding time	J:250145
	increased hemoglobin content	J:250145
	increased mean platelet volume	J:250145
	thrombocytopenia	J:250145
Vwf^tm1.1Vhf/Vwf⁺ involves: C57BL/6J * C57BL/6N	abnormal blood coagulation	J:295694
	abnormal platelet physiology	J:295694
	decreased susceptibility to induced thrombosis	J:295694
	increased bleeding time	J:295694
Vwf^tm1.1Vhf/Vwf^tm1.1Vhf involves: C57BL/6J * C57BL/6N	abnormal blood coagulation	J:295694
	abnormal platelet physiology	J:295694
	decreased susceptibility to induced thrombosis	J:295694
	increased bleeding time	J:295694
Vwf^tm1Wgr/Vwf⁺ involves: 129S2/SvPas * C57BL/6J	abnormal blood coagulation	J:49083
Vwf^tm1Wgr/Vwf^tm1Wgr B6.129S2-Vwf^tm1Wgr	decreased susceptibility to induced thrombosis	J:133469
	impaired blood-brain barrier function	J:140334
	increased susceptibility to bacterial infection	J:140334
	increased susceptibility to experimental autoimmune encephalomyelitis	J:140334
Vwf^tm1Wgr/Vwf^tm1Wgr involves: 129S2/SvPas	decreased myocardial infarct size	J:148295
Vwf^tm1Wgr/Vwf^tm1Wgr involves: 129S2/SvPas	decreased susceptibility to ischemic brain injury	J:148295
Vwf^tm1Wgr/Vwf^tm1Wgr involves: 129S2/SvPas * C57BL/6J	abnormal blood coagulation	J:49083
	abnormal platelet physiology	J:49083
	decreased susceptibility to induced thrombosis	J:63750
	increased bleeding time	J:49083
	increased partial thromboplastin time	J:49083
	internal hemorrhage	J:49083
	melena	J:49083
Vwf^tm2.1Diac/Vwf^tm2.1Diac Not Specified	normal homeostasis/metabolism phenotype	J:220792
	impaired blood coagulation	J:220792
	increased bleeding time	J:220792

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