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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tpo
thyroid peroxidase
MGI:98813
44 phenotypes from 4 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Tpoem1(IMPC)H/Tpo+
C57BL/6NTac-Tpoem1(IMPC)H/H
decreased circulating glucose level J:211773
improved glucose tolerance J:211773
increased mean platelet volume J:211773
Tpoem1(IMPC)H/Tpoem1(IMPC)H
C57BL/6NTac-Tpoem1(IMPC)H/H
abnormal coat/ hair morphology J:211773
abnormal forelimb morphology J:211773
abnormal gait J:211773
abnormal hindlimb morphology J:211773
abnormal startle reflex J:211773
decreased exploration in new environment J:211773
decreased spleen weight J:211773
impaired righting response J:211773
increased circulating aspartate transaminase level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating iron level J:211773
limb grasping J:211773
preweaning lethality, incomplete penetrance J:211773
tremors J:211773
TpoR479C/TpoR479C
involves: ICR
abnormal enzyme/coenzyme activity J:112930
abnormal thyroid follicle morphology J:112930
abnormal thyroid follicular cell morphology J:112930
decreased body size J:112930
decreased body weight J:112930
decreased erythrocyte cell number J:112930
decreased hematocrit J:112930
disproportionate dwarf J:112930
enlarged thyroid gland J:112930
exophthalmos J:112930
increased circulating thyroid-stimulating hormone level J:112930
premature death J:112930
prominent forehead J:112930
small spleen J:112930
Tpotee-2J/Tpotee-2J
B6.Cg-Tpotee-2J H2g7/GrsrJ
abnormal cochlea morphology J:202956
abnormal tectorial membrane morphology J:202956
abnormal thyroid follicle morphology J:202956
abnormal thyroid gland development J:202956
abnormal thyroid gland morphology J:202956
abnormal thyroid gland physiology J:202956
decreased activity of thyroid gland J:202956
delayed inner ear development J:202956
increased or absent threshold for auditory brainstem response J:202956
proportional dwarf J:202956
small thyroid gland J:202956
Tpotee-2J/Tpotee-2J
C3.B6(NOD)-Tpotee-2J/Kjn
increased or absent threshold for auditory brainstem response J:202956
proportional dwarf J:202956
Tpotee/Tpotee
C57BL/6J-Tpotee/GrsrJ
abnormal cochlea morphology J:202956
abnormal femur morphology J:202956
abnormal tectorial membrane morphology J:202956
abnormal thyroid follicle morphology J:202956
abnormal thyroid gland development J:202956
abnormal thyroid gland morphology J:202956
abnormal thyroid gland physiology J:202956
decreased activity of thyroid gland J:202956
delayed inner ear development J:202956
increased or absent threshold for auditory brainstem response J:202956
proportional dwarf J:202956
small thyroid gland J:202956
normal vision/eye phenotype J:202956

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory