111 phenotypes from 7 alleles in 19 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ift88cbbs/Ift88cbbs B6.Cg-Mapttm1(EGFP)Klt Ift88cbbs	abnormal cardiovascular development	J:142500
	abnormal coronary sinus morphology	J:142500
	abnormal forebrain morphology	J:142500
	abnormal lung development	J:142500
	abnormal nervous system development	J:142500
	abnormal telencephalon morphology	J:142500
	absent pulmonary artery	J:142500
	anomalous pulmonary venous connection	J:142500
	atrial septal defect	J:142500
	coloboma	J:142500
	common atrium	J:142500
	embryonic lethality during organogenesis, incomplete penetrance	J:142500
	exencephaly	J:142500
	lethality throughout fetal growth and development, incomplete penetrance	J:142500
	normal nervous system phenotype	J:142500
	persistent truncus arteriosus	J:142500
	polydactyly	J:142500
	pulmonary hypoplasia	J:142500
	normal respiratory system phenotype	J:142500
	ventricular septal defect	J:142500
Ift88cbbs/Ift88tm1.1Bky involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	abnormal direction of heart looping	J:142500
	abnormal lateral ganglionic eminence morphology	J:142500
	abnormal medial ganglionic eminence morphology	J:142500
	abnormal nervous system development	J:142500
	abnormal telencephalon morphology	J:142500
	coloboma	J:142500
	midbrain hyperplasia	J:142500
Ift88fxo/Ift88fxo C3.B6J-Ift88fxo	abnormal floor plate morphology	J:86437
	abnormal midbrain morphology	J:86437
	embryonic lethality during organogenesis, complete penetrance	J:86437
	polydactyly	J:86437
Ift88fxo/Ift88fxo involves: C3HeB/FeJ * C57BL/6J	abnormal diencephalon morphology	J:98216
	abnormal left-right axis patterning	J:98216
	absent floor plate	J:98216
	embryonic lethality during organogenesis, complete penetrance	J:98216
	polydactyly	J:98216
Ift88fxo/Ift88tm1Rpw involves: 129/Sv * C3HeB/FeJ * C57BL/6J	abnormal cranial flexure morphology	J:86437
	abnormal floor plate morphology	J:86437
	embryonic growth arrest	J:86437
	embryonic lethality during organogenesis, complete penetrance	J:86437
	preaxial polydactyly	J:86437
Ift88Tg737Rpw/Ift88Tg737Rpw C3.FVB-Ift88Tg737Rpw	abnormal bile duct morphology	J:18508, J:73583
	abnormal oval cell physiology	J:18508
	abnormal pancreatic duct morphology	J:73583
	absent oval cells	J:73583
	decreased urine osmolality	J:73583
	increased bile salt level	J:73583
	increased circulating alkaline phosphatase level	J:73583
	kidney cyst	J:18508, J:73583
	liver fibrosis	J:18508, J:73583
	polydactyly	J:18508
Ift88Tg737Rpw/Ift88Tg737Rpw FVB/N-Ift88Tg737Rpw	abnormal bile duct morphology	J:18508, J:37149
	abnormal liver parenchyma morphology	J:18508, J:37149
	abnormal pancreas physiology	J:95813
	abnormal pancreas secretion	J:95813
	abnormal pancreatic acinus morphology	J:95813
	abnormal pancreatic duct morphology	J:73583
	decreased circulating glucose level	J:95813
	decreased pancreatic acinar cell number	J:73583
	decreased pancreatic primary cilium length	J:95813
	decreased pancreatic primary cilium number	J:95813
	decreased urine osmolality	J:73583
	disheveled coat	J:18508
	enlarged kidney	J:18508
	impaired glucose tolerance	J:95813
	increased bile salt level	J:73583
	increased circulating alkaline phosphatase level	J:73583
	liver fibrosis	J:18508, J:37149
	pancreas cyst	J:73583, J:95813
	polycystic kidney	J:18508, J:73583
	polydactyly	J:18508
	postnatal growth retardation	J:18508
	postnatal lethality, incomplete penetrance	J:18508, J:37149
	small pancreas	J:95813
Ift88Tg737Rpw/Ift88Tg737Rpw involves: 129/Sv * FVB/N	abnormal bile duct morphology	J:62025
	abnormal pancreatic duct morphology	J:62025
	dilated proximal convoluted tubule	J:62025
	kidney cyst	J:62025
	pancreatic acinar cell atrophy	J:62025
	polydactyly	J:62025
Ift88Tg737Rpw/Ift88Tg737Rpw involves: C3H * FVB/N	abnormal liver morphology	J:73583
	abnormal pancreas morphology	J:73583
	kidney cyst	J:73583
Ift88Tg737Rpw/Ift88Tg737Rpw involves: FVB/N	abnormal carpal bone morphology	J:83305
	abnormal coronal suture morphology	J:83305
	abnormal inner ear morphology	J:83305
	abnormal limb bud morphology	J:83305
	abnormal long bone morphology	J:83305
	abnormal pancreas morphology	J:90990
	abnormal pancreas secretion	J:90990
	abnormal pancreatic acinar cell morphology	J:90990
	abnormal pancreatic duct morphology	J:90990
	abnormal phalanx morphology	J:83305
	abnormal renal tubule epithelial cell primary cilium morphology	J:65500
	abnormal tarsal bone morphology	J:83305
	cleft secondary palate	J:83305
	decreased pancreatic primary cilium length	J:90990
	decreased pancreatic primary cilium number	J:90990
	pancreas cyst	J:90990
	polydactyly	J:83305
	small pancreas	J:90990
	supernumerary molars	J:83305
Ift88Tg737Rpw/Ift88tm1Rpw involves: 129/Sv * FVB/N	abnormal bile duct morphology	J:62025
	abnormal liver morphology	J:62025
	abnormal pancreatic duct morphology	J:62025
	dilated proximal convoluted tubule	J:62025
	kidney cyst	J:62025
	pancreatic acinar cell atrophy	J:62025
	preaxial polydactyly	J:62025
Ift88tm1.1(KOMP)Vlcg/Ift88tm1.1(KOMP)Vlcg C57BL/6N-Ift88tm1.1(KOMP)Vlcg/J	abnormal embryo size	J:211773
	abnormal embryo turning	J:211773
	embryonic growth retardation	J:211773
	preweaning lethality, complete penetrance	J:211773
Ift88tm1.1Bky/Ift88tm1.1Bky involves: 129P2/OlaHsd	abnormal heart looping	J:297055
	absent embryonic cilia	J:297055
	embryonic lethality prior to organogenesis	J:297055
	pericardial effusion	J:297055
Ift88tm1Bky/Ift88tm1.1Bky involves: 129P2/OlaHsd	abnormal limb bud morphology	J:117033
Ift88tm1Bky/Ift88tm1.1Bky Tg(Prrx1-cre)1Cjt/? involves: 129P2/OlaHsd * C57BL/6J * SJL/J	abnormal bone mineralization	J:117033
	abnormal chondrocyte morphology	J:117033
	abnormal limb bud morphology	J:117033
	abnormal osteoblast morphology	J:117033
	abnormal perichondrium morphology	J:117033
	abnormal skeleton development	J:117033
	decreased body size	J:117033
	decreased length of long bones	J:117033
	decreased long bone epiphyseal plate size	J:117033
	disorganized long bone epiphyseal plate	J:117033
	polydactyly	J:117033
	short limbs	J:117033
Ift88tm1Bky/Ift88tm1Bky Nfatc1tm1.1(cre)Bz/Nfatc1+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal mitral valve cusp morphology	J:291454
	abnormal mitral valve morphology	J:291454
	abnormal motile cilium morphology	J:291454
Ift88tm1Bky/Ift88tm1Bky Shhtm1(EGFP/cre)Cjt/Shh+ involves: 129P2/OlaHsd	abnormal palatal rugae morphology	J:281425
Ift88tm1Bky/Ift88tm1Bky Tg(Col1a1-cre)1Bek/0 involves: 129 * 129P2/OlaHsd * CD-1	atrioventricular septal defect	J:308860
	complete atrioventricular septal defect	J:308860
	double outlet right ventricle	J:308860
Ift88tm1Bky/Ift88tm1Bky Tg(Col2a1-cre)1Bhr/? involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal long bone epiphyseal plate morphology	J:121342
	disproportionate dwarf	J:121342
Ift88tm1Bky/Ift88tm1Rpw Tg(Col1a1-cre)1Bek/0 involves: 129 * 129P2/OlaHsd * CD-1	abnormal dorsal mesocardium morphology	J:308860
	anomalous pulmonary venous connection	J:308860
	atrioventricular septal defect	J:308860
	complete atrioventricular septal defect	J:308860
	double outlet right ventricle	J:308860
	persistent truncus arteriosus	J:308860
Ift88tm1Rpw/Ift88tm1.1Bky involves: 129 * 129P2/OlaHsd	abnormal neural tube morphology	J:117033
	distended pericardium	J:117033
	open neural tube	J:117033
Ift88tm1Rpw/Ift88tm1Rpw FVB.129-Ift88tm1Rpw	abnormal direction of heart looping	J:62025
	abnormal forebrain development	J:62025
	abnormal hindbrain development	J:62025
	abnormal left-right axis patterning	J:62025
	abnormal midbrain development	J:62025
	abnormal pharyngeal arch morphology	J:62025
	absent embryonic cilia	J:62025
	broad limb buds	J:62025
	distended pericardium	J:62025
	embryonic growth retardation	J:62025
	embryonic lethality during organogenesis, complete penetrance	J:62025
	kinked neural tube	J:62025
	wavy neural tube	J:62025
Ift88tm1Rpw/Ift88tm1Rpw involves: 129	abnormal limb bud morphology	J:83305
	polydactyly	J:83305