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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sod1
superoxide dismutase 1, soluble
MGI:98351
61 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Fancctm1Mab/Fancctm1Mab
Sod1tm1Cep/Sod1tm1Cep
involves: 129S1/Sv * 129X1/SvJ
abnormal bone marrow cell morphology/development J:71134
abnormal bone marrow morphology J:71134
abnormal common lymphocyte progenitor cell morphology J:71134
abnormal hepatocyte physiology J:71134
abnormal lymphocyte morphology J:71134
decreased bone marrow cell number J:71134
decreased common myeloid progenitor cell number J:71134
decreased erythrocyte cell number J:71134
decreased hemoglobin content J:71134
decreased leukocyte cell number J:71134
decreased lymphocyte cell number J:71134
decreased neutrophil cell number J:71134
increased mean corpuscular volume J:71134
microvesicular hepatic steatosis J:71134
pale liver J:71134
polychromatophilia J:71134
Tg(Sod1*G86R)M1Jwg/0
involves: C57BL/6 * FVB/N
abnormal eye electrophysiology J:59356
paralysis J:59356
premature death J:59356
retina photoreceptor degeneration J:59356
short retina rod cell outer segment J:59356
thin retina outer nuclear layer J:59356
Tg(Sod1*G86R)M1Jwg/0
involves: FVB/N
abnormal adipose tissue morphology J:91800
abnormal circulating hormone level J:91800
abnormal cranial nerve morphology J:22628
abnormal energy expenditure J:91800
abnormal facial motor nucleus morphology J:58733
abnormal fat pad morphology J:91800
abnormal gas homeostasis J:91800
abnormal glucose homeostasis J:91800
abnormal glycerol level J:91800
abnormal hypoglossal nucleus morphology J:58733
abnormal lipid homeostasis J:91800
abnormal motor capabilities/coordination/movement J:22628
abnormal muscle physiology J:91800
abnormal oculomotor nucleus morphology J:58733
abnormal spinal cord dorsal horn morphology J:22628
abnormal spinal cord ventral horn morphology J:22628
abnormal trigeminal motor nucleus morphology J:58733
aphagia J:22628
decreased body weight J:91800
decreased circulating insulin level J:91800
decreased circulating leptin level J:91800
decreased circulating triiodothyronine level J:91800
decreased grip strength J:131028
decreased respiratory quotient J:91800
decreased white adipose tissue amount J:91800
enhanced lipolysis J:91800
impaired adaptive thermogenesis J:91800
impaired balance J:131028
impaired coordination J:131028
increased circulating corticosterone level J:91800
increased circulating glucose level J:91800
increased circulating ketone body level J:91800
increased oxygen consumption J:91800
motor neuron degeneration J:22628
muscle degeneration J:22628
neurodegeneration J:22628
paralysis J:22628
premature death J:22628, J:91800
weakness J:22628
weight loss J:131028
Tg(SOD1*G86R)M3Jwg/0
involves: FVB/N
abnormal motor capabilities/coordination/movement J:22628
abnormal spinal cord ventral horn morphology J:22628
aphagia J:22628
hindlimb paralysis J:22628
motor neuron degeneration J:22628
weakness J:22628

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory