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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Scn5a
sodium channel, voltage-gated, type V, alpha
MGI:98251
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Scn5atm1(SCN5A)Rdn/Scn5atm1(SCN5A)Rdn
involves: 129S6/SvEvTac 		no abnormal phenotype detected J:115269
Scn5atm1(SCN5A)Rdn/Scn5atm3(SCN5A*)Rdn
involves: 129S6/SvEvTac 		decreased cardiac muscle contractility J:189389
decreased heart rate J:189389
dilated cardiomyopathy J:189389
dilated heart left ventricle J:189389
prolonged P wave J:189389
prolonged QRS complex duration J:189389
Scn5atm2.1(SCN5A)Rdn/Scn5atm2.1(SCN5A)Rdn
involves: 129S6/SvEvTac 		abnormal myocardial fiber physiology J:185686
normal cardiovascular system phenotype J:185686
shortened PR interval J:185686
shortened QRS complex duration J:185686
shortened QT interval J:185686
Scn5atm3(SCN5A*)Rdn/Scn5atm3(SCN5A*)Rdn
involves: 129S6/SvEvTac 		abnormal heart electrocardiography waveform feature J:189389
abnormal myocardial fiber physiology J:189389
abnormal sinoatrial node conduction J:189389
atrial fibrillation J:189389
atrioventricular block J:189389
decreased cardiac muscle contractility J:189389
decreased heart rate J:189389
dilated cardiomyopathy J:189389
dilated heart left ventricle J:189389
dilated heart ventricle J:189389
prolonged P wave J:189389
prolonged PR interval J:189389
prolonged QRS complex duration J:189389
ventricular tachycardia J:189389
Scn5atm4(SCN5A)Rdn/Scn5atm4(SCN5A)Rdn
involves: 129S6/SvEvTac 		normal cardiovascular system phenotype J:189389
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory