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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Scd1
stearoyl-Coenzyme A desaturase 1
MGI:98239
95 phenotypes from 8 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Scd1ab-2J/Scd1ab-2J
DBA/1LacJ-Scd1ab-2J/J
abnormal hair cycle J:62699
abnormal hair follicle bulb morphology J:62699
abnormal hair follicle inner root sheath morphology J:62699
abnormal hair follicle morphology J:62699
abnormal hair shaft morphology J:62699
abnormal lipid level J:62699
abnormal sebocyte morphology J:62699
abnormal skin morphology J:62699
acanthosis J:62699
dry skin J:62699
enlarged hair follicles J:62699
flaky skin J:62699
granulomatous inflammation J:62699
hunched posture J:62699
impaired skin barrier function J:62699
increased fluid intake J:62699
matted coat J:62699
orthokeratosis J:62699
parakeratosis J:62699
polyuria J:62699
scaly skin J:62699
sebaceous gland hypoplasia J:62699
small Meibomian gland J:62699
small perianal sebaceous gland J:62699
small sebaceous gland J:62699
sparse hair J:62699
thick dermal layer J:62699
thick epidermis J:62699
Scd1ab-J/Scd1ab-J
ABJ/LeJ-Scd1ab-J
abnormal skin morphology J:62699
dry skin J:62699
flaky skin J:62699
hunched posture J:62699
hyperkeratosis J:62699
normal integument phenotype J:62699
matted coat J:62699
scaly skin J:62699
sparse hair J:62699
thick dermal layer J:62699
Scd1ab-Xyk/Scd1ab-Xyk
Kunming-Scd1ab-Xyk
abnormal hair follicle inner root sheath morphology J:93033
abnormal hair follicle morphology J:93033
abnormal hair follicle outer root sheath morphology J:93033
abnormal hair growth J:93033
abnormal sebocyte morphology J:93033
abnormal skin condition J:93033
abnormal skin morphology J:93033
abnormal skin sebaceous gland morphology J:93033
alopecia J:93033
decreased skin tensile strength J:93033
distorted hair follicle pattern J:93033
dry skin J:93033
eyelids fail to open J:93033
flaky skin J:93033
sebaceous gland hypoplasia J:93033
short hair J:93033
sparse hair J:93033
thick epidermis J:93033
wrinkled skin J:93033
Scd1ab/Scd1ab
involves: BALB/cCrglGa
abnormal cutaneous collagen fibril morphology J:31038
abnormal cutaneous elastic fiber morphology J:31038
abnormal dermal layer morphology J:31038
abnormal estrous cycle J:13143
abnormal hair follicle development J:13143
abnormal hair follicle inner root sheath morphology J:30780
abnormal hair follicle morphology J:30780
abnormal hair growth J:13143
abnormal metabolism J:30359
abnormal piliary canal morphology J:30780
abnormal reproductive system physiology J:13143
abnormal skin morphology J:13143, J:31038
abnormal skin physiology J:5013
alopecia J:13143
blindness J:13143
decreased hair follicle number J:13143
hyperkeratosis J:13143
photophobia J:30359
postnatal growth retardation J:13143
prolonged diestrus J:13143
reduced female fertility J:13143
sebaceous gland hypoplasia J:30359
Scd1flk/Scd1flk
C57BL/6J-Scd1flk
abnormal sebaceous lipid secretion J:100424
alopecia J:100424
flaky skin J:100424
increased susceptibility to bacterial infection J:100424
scaly skin J:100424
sebaceous gland atrophy J:100424
spontaneous skin ulceration J:100424
Scd1Gt(OST102902)Lex/Scd1Gt(OST102902)Lex
involves: 129S5/SvEvBrd * C57BL/6J
decreased percent body fat/body weight J:185494
Scd1tm1Ntam/Scd1tm1Ntam
involves: 129S6/SvEvTac
abnormal cholesterol homeostasis J:71350
decreased circulating insulin level J:78607
decreased unsaturated fatty acids level J:71350
decreased white adipose tissue amount J:78607
improved glucose tolerance J:78607
increased circulating ketone body level J:78607
increased oxygen consumption J:78607
increased saturated fatty acids level J:71350
Meibomian gland atrophy J:71350
narrow eye opening J:71350
polyphagia J:78607
progressive hair loss J:71350
sebaceous gland atrophy J:71350
Scd1tm1Ntam/Scd1tm1Ntam
involves: C57BL/6
abnormal eating behavior J:130441
abnormal glucose homeostasis J:130441
decreased circulating glucose level J:130441
decreased circulating triglyceride level J:130441
decreased liver triglyceride level J:130441
decreased susceptibility to diet-induced hepatic steatosis J:130441
decreased susceptibility to diet-induced obesity J:130441
decreased white adipose tissue amount J:130441
improved glucose tolerance J:130441
increased insulin sensitivity J:130441
Scd1tm2Ntam/Scd1tm2Ntam
Lrig1tm1.1(cre/ERT2)Rjc/Lrig1+
B6.129(Cg)-Lrig1tm1.1(cre/ERT2)Rjc Scd1tm2Ntam
abnormal dermis papillary layer morphology J:325761
abnormal hair follicle matrix region morphology J:325761
abnormal hair shaft morphology J:325761
decreased hair follicle number J:325761
hair follicle degeneration J:325761
Scd1tm2Ntam/Scd1tm2Ntam
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn Scd1tm2Ntam
abnormal fat pad morphology J:130441
abnormal gluconeogenesis J:130441
abnormal lipid homeostasis J:130441
abnormal liver physiology J:130441
normal behavior/neurological phenotype J:130441
decreased circulating glucose level J:130441
decreased circulating triglyceride level J:130441
decreased circulating VLDL triglyceride level J:130441
decreased gonadal fat pad weight J:130441
decreased inguinal fat pad weight J:130441
decreased liver glycogen level J:130441
decreased liver triglyceride level J:130441
decreased retroperitoneal fat pad weight J:130441
decreased susceptibility to diet-induced hepatic steatosis J:130441
decreased susceptibility to diet-induced obesity J:130441
decreased white adipose tissue amount J:130441
normal homeostasis/metabolism phenotype J:130441
increased circulating cholesterol level J:130441

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory