Rasa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rasa1
RAS p21 protein activator 1
MGI:97860

31 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rasa1^{tm1b(EUCOMM)Hmgu}/Rasa1⁺ C57BL/6N-Rasa1^{tm1b(EUCOMM)Hmgu}/J	abnormal behavior	J:211773
	abnormal retina vasculature morphology	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating phosphate level	J:211773
	increased heart weight	J:211773
	increased mean corpuscular hemoglobin	J:211773
	thrombocytopenia	J:211773
Rasa1^{tm1b(EUCOMM)Hmgu}/Rasa1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Rasa1^{tm1b(EUCOMM)Hmgu}/J	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Rasa1^tm1Paw/Rasa1^tm1Paw either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal cell death	J:29825
	abnormal developmental patterning	J:29825
	abnormal embryonic tissue morphology	J:29825
	abnormal first pharyngeal arch morphology	J:29825
	abnormal rostral-caudal axis patterning	J:29825
	decreased embryo size	J:29825
	embryonic growth arrest	J:29825
	embryonic lethality during organogenesis, complete penetrance	J:29825
	excessive folding of visceral yolk sac	J:29825
	incomplete somite formation	J:29825
Rasa1^tm1Wid/Rasa1^tm1Wid involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6N	abnormal cardiovascular system physiology	J:189241
	decreased colon length	J:189241
	increased cardiomyocyte apoptosis	J:189241
	increased cellular sensitivity to ultraviolet irradiation	J:189241
	increased enterocyte apoptosis	J:189241
	increased sensitivity to induced cell death	J:189241
	increased susceptibility to induced colitis	J:189241
Rasa1^tm2.1Pdk/Rasa1^tm2.1Pdk involves: 129S6/SvEvTac * C57BL/6	abnormal blood vessel morphology	J:216433
	abnormal dorsal aorta morphology	J:216433
	abnormal intersomitic artery morphology	J:216433
	abnormal vitelline vasculature morphology	J:216433
	decreased embryo size	J:216433
	distended pericardium	J:216433
	embryonic lethality during organogenesis, complete penetrance	J:216433
	excessive folding of visceral yolk sac	J:216433

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23