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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rasa1
RAS p21 protein activator 1
MGI:97860
26 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rasa1tm1b(EUCOMM)Hmgu/Rasa1+
C57BL/6N-Rasa1tm1b(EUCOMM)Hmgu/J
abnormal bone structure J:211773
abnormal retinal vasculature morphology J:211773
increased body length J:211773
Rasa1tm1b(EUCOMM)Hmgu/Rasa1tm1b(EUCOMM)Hmgu
C57BL/6N-Rasa1tm1b(EUCOMM)Hmgu/J
preweaning lethality, complete penetrance J:211773
Rasa1tm1Paw/Rasa1tm1Paw
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal cell death J:29825
abnormal developmental patterning J:29825
abnormal embryonic tissue morphology J:29825
abnormal first pharyngeal arch morphology J:29825
abnormal rostral-caudal axis patterning J:29825
decreased embryo size J:29825
embryonic growth arrest J:29825
embryonic lethality during organogenesis, complete penetrance J:29825
excessive folding of visceral yolk sac J:29825
incomplete somite formation J:29825
Rasa1tm1Wid/Rasa1tm1Wid
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6N
abnormal cardiovascular system physiology J:189241
decreased colon length J:189241
increased cardiomyocyte apoptosis J:189241
increased cellular sensitivity to ultraviolet irradiation J:189241
increased enterocyte apoptosis J:189241
increased sensitivity to induced cell death J:189241
increased susceptibility to induced colitis J:189241
Rasa1tm2.1Pdk/Rasa1tm2.1Pdk
involves: 129S6/SvEvTac * C57BL/6
abnormal blood vessel morphology J:216433
abnormal dorsal aorta morphology J:216433
abnormal intersomitic artery morphology J:216433
abnormal vitelline vasculature morphology J:216433
decreased embryo size J:216433
distended pericardium J:216433
embryonic lethality during organogenesis, complete penetrance J:216433
excessive folding of visceral yolk sac J:216433

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory