Apoetm1Unc/Apoetm1Unc
Rag2tm1Fwa/Rag2+
involves: 129P2/OlaHsd * 129S/SvEv
|
abnormal aorta morphology |
J:59156
|
|
decreased body weight |
J:59156
|
|
decreased circulating cholesterol level |
J:59156
|
|
decreased circulating HDL cholesterol level |
J:59156
|
|
increased uterus weight |
J:59156
|
Apoetm1Unc/Apoetm1Unc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv
|
abnormal aorta morphology |
J:59156
|
|
decreased body weight |
J:59156
|
|
decreased circulating cholesterol level |
J:59156
|
|
decreased circulating HDL cholesterol level |
J:59156
|
|
increased uterus weight |
J:59156
|
Cbltm1.1Hua/Cbltm1.1Hua
Lcp2tm1Gak/Lcp2tm1Gak
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
|
abnormal T cell differentiation |
J:91369
|
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv
|
increased T cell proliferation |
J:88120
|
Cd8atm1Asin/Cd8atm1Asin
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
|
abnormal CD8-positive, alpha beta T cell morphology |
J:125259
|
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:207289
|
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:207289
|
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:207289
|
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:207289
|
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * BALB/cAnNTac
|
abnormal immune system physiology |
J:177073
|
|
normal
craniofacial phenotype |
J:177073
|
|
normal
hematopoietic system phenotype |
J:177073
|
|
normal
immune system phenotype |
J:177073
|
|
normal
skeleton phenotype |
J:177073
|
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac
|
abnormal response to transplant |
J:168302
|
Ctcftm2Gal/Ctcftm2Gal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Lck-cre)1Cwi/0
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * C57BL/10
|
decreased double-positive T cell number |
J:143271
|
Ctla4tm1Shr/Ctla4tm1Shr
Rag2tm1Fwa/Rag2tm1Fwa
Tg(DO11.10)10Dlo/0
involves: 129S/Sv * BALB/c * C3H * C57BL/6
|
abnormal cytokine secretion |
J:110446
|
|
abnormal T cell physiology |
J:110446
|
|
normal
immune system phenotype |
J:110446
|
Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa
involves: C57BL/6J * C57BL/6NTac
|
abnormal response to transplant |
J:290663
|
Dnajc11spc/Dnajc11spc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S6/SvEvTac * C57BL/6J
|
normal
abnormal behavior |
J:221543
|
Dusp5tm1.1Achn/Dusp5tm1.1Achn
Rag2tm1.1Cgn/Rag2tm1.1Cgn
involves: C57BL/6NCrl
|
abnormal eosinophil physiology |
J:218203
|
|
abnormal susceptibility to parasitic infection |
J:218203
|
|
increased eosinophil cell number |
J:218203
|
Erap1tm1Luc/Erap1tm1Luc
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrLCMV)327Sdz/Tg(TcrLCMV)327Sdz
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * C57BL/10SgSnAi * DBA/2
|
normal
immune system phenotype |
J:122479
|
Errfi1tm1Gvw/Errfi1tm1Gvw
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv
|
osteoarthritis |
J:100927
|
Gata3tm1Jfz/Gata3tm1Jfz
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-cre)1Cwi/0
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
involves: 129S/SvEv * C57BL/6 * DBA/2
|
abnormal T cell differentiation |
J:141145
|
Gpr15tm1.1Litt/Gpr15tm1.1Litt
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraTcrb)425Cbn/0
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6
|
abnormal immune system physiology |
J:199126
|
H2b/H2b
Nfkbidtm1Clay/Nfkbidtm1Clay
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6
|
abnormal thymocyte activation |
J:132071
|
|
decreased interleukin-2 secretion |
J:132071
|
|
decreased T cell proliferation |
J:132071
|
H2b/H2b
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * C57BL/6
|
abnormal cytotoxic T cell physiology |
J:133112
|
|
arrested T cell differentiation |
J:133112
|
|
decreased CD4-positive, alpha-beta T cell number |
J:133112
|
|
increased CD8-positive, alpha-beta T cell number |
J:133112
|
|
increased T cell proliferation |
J:133112
|
H2d/H2d
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * C57BL/6
|
arrested T cell differentiation |
J:133112
|
|
decreased CD4-positive, alpha-beta T cell number |
J:133112
|
|
decreased CD8-positive, alpha-beta T cell number |
J:133112
|
Hgftm1Jmw/Hgftm1Jmw
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
|
decreased hepatocyte proliferation |
J:97145
|
|
impaired liver regeneration |
J:97145
|
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu
Cd79atm1(cre)Reth/Cd79a+
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL
|
decreased pro-B cell number |
J:209928
|
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2+
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
|
abnormal intestinal epithelium morphology |
J:29999
|
|
abnormal intestinal goblet cell morphology |
J:29999
|
|
anemia |
J:29999
|
|
cachexia |
J:29999
|
|
colitis |
J:29999
|
|
diarrhea |
J:29999
|
|
enlarged mesenteric lymph nodes |
J:29999
|
|
hunched posture |
J:29999
|
|
rectal hemorrhage |
J:29999
|
|
rectal prolapse |
J:29999
|
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
|
abnormal blood cell morphology/development |
J:29999
|
|
normal
immune system phenotype |
J:29999
|
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
involves: 129P2/OlaHsd * C57BL/10
|
abnormal T cell number |
J:120176
|
|
increased T-helper 17 cell number |
J:120176
|
Il2rbtm1Mak/Il2rbtm1Mak
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129 * 129S/SvEv
|
decreased NK cell number |
J:142654
|
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac
|
abnormal response to transplant |
J:168302
|
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:168303
|
|
increased susceptibility to bacterial infection |
J:168303
|
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:168301
|
|
thrombocytopenia |
J:168301
|
Il2rgtm1.1Flv/Y
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNTac
|
abnormal response to transplant |
J:168303
|
|
increased susceptibility to bacterial infection |
J:168303
|
Il2rgtm1Cgn/Il2rgtm1Cgn
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv
|
abnormal interleukin secretion |
J:142654
|
|
decreased NK cell number |
J:142654
|
|
increased susceptibility to bacterial infection |
J:142654
|
Il2rgtm1Cgn/Y
Rag2tm1Fwa/Rag2tm1Fwa
B6.129-Rag2tm1Fwa Il2rgtm1Cgn
|
absent B cells |
J:132257
|
|
absent NK cells |
J:132257
|
|
absent T cells |
J:132257
|
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S4/SvJae
|
abnormal interferon secretion |
J:140483
|
|
absent NK cells |
J:140483
|
|
absent T cells |
J:140483
|
|
increased susceptibility to bacterial infection |
J:140483
|
|
increased susceptibility to induced morbidity/mortality |
J:140483
|
|
lung inflammation |
J:140483
|
Il6sttm1Thir/Il6sttm1Thir
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6
|
normal
immune system phenotype |
J:133059
|
Il7tm1Dnax/Il7tm1Dnax
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv
|
decreased NK cell number |
J:132257
|
Il12atm1Jm/Il12atm1Jm
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv * 129S6/SvEvTac
|
abnormal interferon secretion |
J:140483
|
|
decreased susceptibility to bacterial infection |
J:140483
|
|
lung inflammation |
J:140483
|
Il12btm1Jm/Il12btm1Jm
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv
|
abnormal chemokine secretion |
J:140483
|
|
abnormal interferon secretion |
J:140483
|
|
increased susceptibility to bacterial infection |
J:140483
|
|
lung inflammation |
J:140483
|
Il15tm1Imx/Il15tm1Imx
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6
|
decreased NK cell number |
J:132257
|
Il23rtm1.1Ngh/Il23rtm1.1Ngh
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6
|
abnormal circulating interleukin level |
J:216867
|
|
abnormal large intestine crypts of Lieberkuhn morphology |
J:216867
|
|
decreased colon length |
J:216867
|
|
decreased interleukin-17 secretion |
J:216867
|
|
weight loss |
J:216867
|
Lattm6.1(HBEGF/EGFP)Mal/?
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6
|
abnormal T cell physiology |
J:138401
|
Lime1tm1.1Mal/Lime1tm1.1Mal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
B6.Cg-Rag2tm1Fwa Lime1tm1.1Mal Tg(TcraH-Y,TcrbH-Y)1Pas
|
abnormal CD4-positive T cell differentiation |
J:126321
|
|
increased CD4-positive, alpha-beta T cell number |
J:126321
|
Mmp9tm1Tvu/Mmp9tm1Tvu
Rag2tm1Fwa/Rag2tm1Fwa
B6.129S-Rag2tm1Fwa Mmp9tm1Tvu
|
decreased tumor incidence |
J:105098
|
Mmp9tm1Tvu/Mmp9tm1Tvu
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * FVB/N
|
abnormal tumor morphology |
J:140033
|
|
decreased metastatic potential |
J:140033
|
|
decreased tumor growth/size |
J:140033
|
Mogtm1Dpd/Mogtm1Dpd
Rag2tm1Cgn/Rag2tm1Cgn
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * C57BL/6
|
increased susceptibility to experimental autoimmune encephalomyelitis |
J:151335
|
Nfkbiztm1Aki/Nfkbiztm1Aki
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv
|
normal
immune system phenotype |
J:194832
|
Nr3c1tm1.1Jda/Nr3c1tm1.1Jda
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(Lck-cre)548Jxm/0
Tg(TcrAND)53Hed/0
B6.Cg-Rag2tm1.1Cgn Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm Tg(TcrAND)53Hed
|
decreased double-positive T cell number |
J:189951
|
Pdpk1tm1.1Mlw/Pdpk1tm1.1Mlw
Rag2tm1Fwa/Rag2tm1Fwa
Tnfrsf4tm2(cre)Nik/Tnfrsf4+
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
involves: 129S/SvEv * 129X1/SvJ * C57BL/6
|
abnormal keratinocyte differentiation |
J:226194
|
|
dermatitis |
J:226194
|
|
epidermal hyperplasia |
J:226194
|
|
premature death |
J:226194
|
Prss16tm1.1Mal/Prss16+
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6
|
abnormal positive T cell selection |
J:148034
|
|
decreased CD4-positive, alpha-beta T cell number |
J:148034
|
|
decreased single-positive T cell number |
J:148034
|
|
lymph node hypoplasia |
J:148034
|
Prss16tm1.1Mal/Prss16tm1.1Mal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6
|
abnormal positive T cell selection |
J:148034
|
|
decreased CD4-positive, alpha-beta T cell number |
J:148034
|
|
decreased double-positive T cell number |
J:148034
|
|
decreased single-positive T cell number |
J:148034
|
|
lymph node hypoplasia |
J:148034
|
|
spleen hypoplasia |
J:148034
|
|
thymus hypoplasia |
J:148034
|
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0
involves: C57BL/6 * DBA/2
|
autoimmune response |
J:134764
|
|
CNS inflammation |
J:134764
|
|
demyelination |
J:134764
|
|
hindlimb paralysis |
J:134764
|
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6
|
normal
immune system phenotype |
J:181257
|
|
normal
mortality/aging |
J:181257
|
Rag2tm1.1Desi/Rag2tm1.1Desi
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
|
increased B cell derived lymphoma incidence |
J:168974
|
|
increased T cell derived lymphoma incidence |
J:168974
|
Rag2tm1.1Mss/Rag2tm1.1Mss
involves: 129S6/SvEvTac
|
abnormal lymphopoiesis |
J:171970
|
|
abnormal pre-B cell morphology |
J:171970
|
|
decreased pre-B cell number |
J:171970
|
|
increased DN3 thymocyte number |
J:171970
|
|
normal
neoplasm |
J:170462
|
Rag2tm1.1Mss/Rag2tm1.1Mss
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129S6/SvEvTac
|
abnormal chromosome morphology |
J:170462
|
|
aneuploidy |
J:170462
|
|
increased lymphoma incidence |
J:170462
|
|
increased T cell derived lymphoma incidence |
J:170462
|
|
premature death |
J:170462
|
Rag2tm1Cgn/Rag2tm1Cgn
Xrcc4tm1Fwa/Xrcc4tm2Fwa
Tg(Cr2-cre)3Cgn/?
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
|
abnormal class switch recombination |
J:150339
|
|
spontaneous chromosome breakage |
J:150339
|
Rag2tm1Fwa/Rag2+
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6J
|
increased T cell derived lymphoma incidence |
J:47667
|
|
premature death |
J:47667
|
Rag2tm1Fwa/Rag2+
Tg(LPV-TAg1135)11Tvd/0
involves: 129S/SvEv * C57BL/6 * DBA/2
|
increased T cell derived lymphoma incidence |
J:47667
|
|
premature death |
J:47667
|
Rag2tm1Fwa/Rag2tm1Fwa
Cd47tm1Fpl/Cd47tm1Fpl
Il2rgtm1Cgn/Y
involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6
|
absent peripheral lymph nodes |
J:203904
|
|
decreased CD4-positive, alpha-beta T cell number |
J:203904
|
|
decreased lymphocyte cell number |
J:203904
|
|
decreased susceptibility to graft versus host disease |
J:203904
|
|
increased activated T cell number |
J:203904
|
|
increased CD8-positive, alpha-beta T cell number |
J:203904
|
|
increased susceptibility to Retroviridae infection |
J:203904
|
Rag2tm1Fwa/Rag2tm1Fwa
Rnaseh2atm1Crh/Rnaseh2atm1Crh
involves: 129S/SvEv
|
perinatal lethality, complete penetrance |
J:232933
|
Rag2tm1Fwa/Rag2tm1Fwa
Rr299391tm1.1Fwa/Rr299391tm1.1Fwa
involves: 129P2/OlaHsd * 129S/SvEv
|
abnormal T cell receptor delta chain V(D)J recombination |
J:149413
|
Rag2tm1Fwa/Rag2tm1Fwa
Sos1tm1.1Les/Sos1tm1.1Les
Tg(Lck-cre)1Cwi/0
involves: 129S/SvEv * C57BL/6
|
abnormal T cell differentiation |
J:174536
|
|
decreased T cell proliferation |
J:174536
|
Rag2tm1Fwa/Rag2tm1Fwa
Stat1tm1Rds/Stat1tm1Rds
involves: 129S/SvEv * 129S6/SvEvTac
|
increased gastrointestinal tumor incidence |
J:216040
|
|
increased mammary adenocarcinoma incidence |
J:216040
|
Rag2tm1Fwa/Rag2tm1Fwa
Tbatatm1Faf/Tbatatm1Faf
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
|
abnormal bone marrow cell physiology |
J:166065
|
|
abnormal T cell differentiation |
J:166065
|
|
increased thymocyte number |
J:166065
|
Rag2tm1Fwa/Rag2tm1Fwa
Tbx21tm1Glm/Tbx21tm1Glm
involves: 129S/SvEv * 129S6/SvEvTac
|
abnormal digestive system physiology |
J:141481
|
|
abnormal intestinal epithelium morphology |
J:141481
|
|
abnormal large intestine crypts of Lieberkuhn morphology |
J:141481
|
|
colitis |
J:141481
|
|
normal
digestive/alimentary phenotype |
J:141481
|
|
increased tumor necrosis factor secretion |
J:141481
|
|
large intestinal inflammation |
J:141481
|
|
rectal prolapse |
J:141481
|
Rag2tm1Fwa/Rag2tm1Fwa
TcraLn3Jae/Tcra+
TcrbLn3Jae/Tcrb+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6
|
abnormal double-negative T cell morphology |
J:143006
|
|
absent gamma-delta T cells |
J:143006
|
|
decreased CD4-positive, alpha-beta T cell number |
J:143006
|
|
increased CD8-positive, alpha-beta T cell number |
J:143006
|
Rag2tm1Fwa/Rag2tm1Fwa
TcrbLn3Jae/Tcrb+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6
|
abnormal double-negative T cell morphology |
J:143006
|
|
absent gamma-delta T cells |
J:143006
|
|
decreased CD4-positive, alpha-beta T cell number |
J:143006
|
|
increased double-positive T cell number |
J:143006
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-NPM/ALK)N1Ingh/0
involves: 129S/SvEv * C57BL/6 * Swiss Webster
|
increased DN3 thymocyte number |
J:235890
|
|
increased T cell derived lymphoma incidence |
J:235890
|
|
increased thymus tumor incidence |
J:235890
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-NPM/ALK)N1Ingh/0
Tg(TcraTcrb)1100Mjb/0
involves: 129S/SvEv * C57BL/6 * Swiss Webster
|
increased gastrointestinal stromal tumor incidence |
J:235890
|
|
increased hepatocellular carcinoma incidence |
J:235890
|
|
increased sarcoma incidence |
J:235890
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(DO11.10)10Dlo/0
involves: 129S/SvEv * BALB/c * C3H * C57BL/6
|
normal
immune system phenotype |
J:110446
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(EmuSR-tTa)83Bop/0
Tg(tetO-Nfatct1*)1Grc/0
involves: 129S/SvEv * C57BL/6J * CBA/J * FVB/N
|
abnormal double-positive T cell morphology |
J:141917
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Igh-Pim1)1Brn/0
involves: 129S/SvEv * C57BL/6LiA * CBA
|
decreased thymocyte number |
J:114561
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(KRT14-Il1f6)1Hblu/?
involves: 129S/SvEv * C57BL/6 * DBA/2
|
abnormal skin morphology |
J:126327
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Lck-Akt1*)M-1Pnt/0
involves: 129S/SvEv * C3H/He * C57BL/6
|
absent CD4-positive, alpha-beta T cells |
J:135903
|
|
absent CD8-positive, alpha-beta T cells |
J:135903
|
|
increased double-positive T cell number |
J:135903
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(LPV-TAg1135)11Tvd/0
involves: 129S/SvEv * C57BL/6 * DBA/2
|
increased T cell derived lymphoma incidence |
J:47667
|
|
premature death |
J:47667
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra5CC7,Tcrb5CC7)IWep/?
Themis5AT161/Themis5AT161
involves: 129S/SvEv * C57BL/6
|
arrested T cell differentiation |
J:151076
|
|
increased double-positive T cell number |
J:151076
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0
involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * DBA/2
|
abnormal CD4-positive T cell differentiation |
J:125548
|
|
abnormal positive T cell selection |
J:125548
|
|
decreased CD4-positive, alpha-beta T cell number |
J:125548
|
|
increased double-positive T cell number |
J:125548
|
|
thymus hyperplasia |
J:125548
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraCN.B1,TcrbCN.B1)SM1Jen/0
involves: 129S/SvEv * C57BL/6
|
increased susceptibility to bacterial infection induced morbidity/mortality |
J:162539
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * C57BL/6J * DBA/2J
|
abnormal CD8-positive, alpha beta T cell morphology |
J:125259
|
|
abnormal CD8-positive, alpha-beta T cell physiology |
J:125259
|
|
abnormal cytotoxic T cell physiology |
J:66565
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
Themis5AT161/Themis5AT161
involves: 129S/SvEv * C57BL/6 * DBA/2
|
decreased single-positive T cell number |
J:151076
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraTcrbNY8.3)1Pesa/0
NOD.Cg-Rag2tm1Fwa Tg(TcraTcrbNY8.3)1Pesa
|
increased circulating glucose level |
J:94192
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrHEL3A9)1Mmd/0
involves: 129S/SvEv * C57BL/6
|
abnormal CD4-positive, alpha beta T cell morphology |
J:78309
|
|
abnormal double-positive T cell morphology |
J:78309
|
|
abnormal T cell activation |
J:78309
|
|
abnormal T cell proliferation |
J:78309
|
|
abnormal thymus cell ratio |
J:78309
|
|
decreased CD4-positive, alpha-beta T cell number |
J:78309
|
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrHEL3A9)1Mmd/0
Tg(TLK2mHEL)2Ccg/0
involves: 129S/SvEv * C57BL/6
|
abnormal CD4-positive, alpha beta T cell morphology |
J:78309
|
|
abnormal CD4-positive, alpha-beta T cell physiology |
J:78309
|
|
abnormal T cell activation |
J:78309
|
|
abnormal T cell proliferation |
J:78309
|
|
decreased CD4-positive, alpha-beta T cell number |
J:78309
|
|
decreased double-positive T cell number |
J:78309
|
|
thyroid gland inflammation |
J:78309
|
Rag2tm1Fwa/Rag2tm1Fwa
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6J
|
increased T cell derived lymphoma incidence |
J:47667
|
|
premature death |
J:47667
|
Rag2tm1Fwa/Rag2tm1Fwa
Unc93b1tm1.1Kmiy/Unc93b1tm1.1Kmiy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
|
normal
hematopoietic system phenotype |
J:174308
|
|
normal
mortality/aging |
J:174308
|
Rag2tm1Fwa/Rag2tm1Fwa
Wdr1rede/Wdr1rede
involves: 129S/SvEv * C57BL/6
|
abnormal immune system physiology |
J:134092
|
|
thrombocytopenia |
J:134092
|
Rag2tm2.1Desi/Rag2tm2.1Desi
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
|
increased T cell derived lymphoma incidence |
J:168974
|
Rr148tm1.1Fwa/Rr148tm1.1Fwa
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac
|
abnormal B cell differentiation |
J:101400
|
Rr148tm1Fwa/Rr148tm1Fwa
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac
|
abnormal B cell differentiation |
J:101400
|
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