33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Braftm1Sva/Braf+ Raf1tm2Bacc/Raf1tm2Bacc Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	no abnormal phenotype detected	J:121660
Braftm1Sva/Braftm1.1Sva Raf1tm1Bacc/Raf1tm2Bacc Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal axon extension	J:121660
	abnormal dorsal root ganglion morphology	J:121660
	abnormal innervation	J:121660
	embryonic lethality during organogenesis, complete penetrance	J:121660
Braftm1Sva/Braftm1Sva Krastm1Bbd/Kras+ Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Raf1tm2Bacc/Raf1tm2Bacc involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	decreased cell proliferation	J:172200
Braftm1Sva/Braftm1Sva Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Raf1tm2Bacc/Raf1tm2Bacc involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:172200
Braftm1Sva/Braftm1Sva Raf1tm2Bacc/Raf1+ Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal dorsal root ganglion morphology	J:121660
	abnormal innervation	J:121660
	abnormal sensory neuron innervation pattern	J:121660
	postnatal growth retardation	J:121660
	postnatal lethality, incomplete penetrance	J:121660
Braftm1Sva/Braftm1Sva Raf1tm2Bacc/Raf1tm2Bacc involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal axon extension	J:121660
Braftm1Wds/Braf+ Raf1tm2Bacc/Raf1tm2Bacc Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	no abnormal phenotype detected	J:121660
Braftm1Wds/Braftm1.1Wds Raf1tm1Bacc/Raf1tm2Bacc Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal axon extension	J:121660
	abnormal dorsal root ganglion morphology	J:121660
	abnormal innervation	J:121660
	embryonic lethality during organogenesis, complete penetrance	J:121660
Braftm1Wds/Braftm1Wds Raf1tm2Bacc/Raf1+ Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal dorsal root ganglion morphology	J:121660
	abnormal innervation	J:121660
	abnormal sensory neuron innervation pattern	J:121660
	postnatal growth retardation	J:121660
	postnatal lethality, incomplete penetrance	J:121660
Braftm1Wds/Braftm1Wds Raf1tm2Bacc/Raf1tm2Bacc involves: 129P2/OlaHsd * C57BL/6	abnormal axon extension	J:121660
Braftm1Wds/Braftm1Wds Raf1tm2Bacc/Raf1tm2Bacc H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129P2/OlaHsd * C57BL/6J * CBA/J	abnormal conotruncus morphology	J:144862
	abnormal thyroid gland morphology	J:144862
	double outlet right ventricle	J:144862
	normal growth/size/body region phenotype	J:144862
	normal hearing/vestibular/ear phenotype	J:144862
	lethality throughout fetal growth and development, complete penetrance	J:144862
	mandible hypoplasia	J:144862
	persistent truncus arteriosus	J:144862
	short maxilla	J:144862
	small thymus	J:144862
	small thyroid gland	J:144862
	ventricular septal defect	J:144862
Faslpr/Fas+ Raf1tm1Bacc/Raf1+ involves: 129/SvHsd * 129P2/OlaHsd * C57BL/6 * MRL	normal hematopoietic system phenotype	J:135681
Faslpr/Fas+ Raf1tm1Bacc/Raf1tm1Bacc involves: 129/SvHsd * 129P2/OlaHsd * C57BL/6 * MRL	abnormal erythropoiesis	J:135681
	normal hematopoietic system phenotype	J:135681
	normal mortality/aging	J:135681
Faslpr/Faslpr Raf1tm1Bacc/Raf1tm1Bacc involves: 129/SvHsd * 129P2/OlaHsd * C57BL/6 * MRL	abnormal erythropoiesis	J:135681
	increased apoptosis	J:135681
Krastm1Bbd/Kras+ Raf1tm2Bacc/Raf1tm2Bacc involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	decreased classified tumor incidence	J:172200
	premature death	J:172200
Krastm1Bbd/Kras+ Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd Raf1tm2Bacc/Raf1tm2Bacc involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	decreased cell proliferation	J:172200
Krastm4Tyj/Kras+ Raf1tm2Bacc/Raf1tm2Bacc Ptf1atm1(cre)Hnak/Ptf1a+ involves: 129P2/OlaHsd * 129S4/SvJae	increased pancreatic ductal adenocarcinoma incidence	J:197054
Map3k5tm1Hijo/Map3k5tm1Hijo Raf1tm2Bacc/Raf1tm2Bacc Tg(Myh6-cre)2182Mds/0 involves: C57BL/6J	normal cardiovascular system phenotype	J:93418
Raf1TgTn(sb-cHS4,Tyr)2526AOve/Raf1TgTn(sb-cHS4,Tyr)2526AOve FVB/N-Raf1TgTn(sb-cHS4,Tyr)2526AOve	embryonic lethality during organogenesis	J:175597
Raf1tm3Ulb/Raf1tm3Ulb Not Specified	decreased cell proliferation	J:141095
	embryonic growth retardation	J:141095
	embryonic lethality during organogenesis, complete penetrance	J:141095
	increased embryonic tissue cell apoptosis	J:141095
	increased sensitivity to induced cell death	J:141095