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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rac1
Rac family small GTPase 1
MGI:97845
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Rac1tm1Tyb/Rac1tm1Tyb
Rac2tm1Mddw/Rac2tm1Mddw
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6
arrested B cell differentiation J:86765
decreased B cell number J:86765
decreased B-1 B cell number J:86765
decreased follicular B cell number J:86765
decreased marginal zone B cell number J:86765
decreased transitional stage B cell number J:86765
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Rac1tm1Djk/Rac1+
Tg(Msx2-cre)5Rem/0
involves: 129S4/SvJae
abnormal forelimb morphology J:145305
absent hindlimb J:145305
Grhl3tm1(cre)Cgh/Grhl3+
Gt(ROSA)26Sortm1(ptxA)Cgh/Gt(ROSA)26Sor+
Rac1tm1Djk/Rac1tm1Djk
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * SJL
exencephaly J:157446
spina bifida J:157446
Gt(ROSA)26Sortm1(Dkk1)Flng/Gt(ROSA)26Sor+
Rac1tm1Djk/Rac1+
Tg(Msx2-cre)5Rem/0
involves: 129S4/SvJae * 129X1/SvJ
absent hindlimb J:145305
short forelimb J:145305
Gt(ROSA)26Sortm9(Rac1*,EGFP)Rsky/Gt(ROSA)26Sor+
Ptf1atm1(cre)Hnak/Ptf1a+
involves: C57BL/6
normal endocrine/exocrine gland phenotype J:197054
normal neoplasm J:197054
Gt(ROSA)26Sortm9(Rac1*,EGFP)Rsky/Gt(ROSA)26Sortm9(Rac1*,EGFP)Rsky
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0
involves: 129P2/OlaHsd * C57BL/6
decreased mature B cell number J:157297
Hprt1tm1(tetO-EGFP/Rac1*)Shaw/Y
involves: 129S4/SvJae * C57BL/6
normal renal/urinary system phenotype J:206088
Hprt1tm1(tetO-EGFP/Rac1*)Shaw/Y
Tg(Nphs1-rtTA*3G)8Jhm/0
involves: 129S4/SvJae * C57BL/6
increased urine protein level J:206088
normal renal/urinary system phenotype J:206088
Hprt1tm1(tetO-EGFP/Rac1*)Shaw/Y
Tg(NPHS2-rtTA2*M2)1Jbk/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
increased urine protein level J:206088
podocyte foot process effacement J:206088
Ptentm1Ppp/Pten+
Rac1tm1Tyb/Rac1tm2Tyb
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/Sv * C3H * C57BL/6 * CBA
abnormal apoptosis J:173526
abnormal embryo development J:173526
Rac1tm1Djk/Rac1tm1Djk
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Tg(Mef2c-cre)2Blk/0
involves: 129 * BALB/c * C57BL/6 * C57BL/6J
abnormal interventricular septum muscular part morphology J:315097
decreased cell migration J:315097

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory