About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pth1r
parathyroid hormone 1 receptor
MGI:97801
65 phenotypes from 6 alleles in 9 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Pth1rtm1a(EUCOMM)Hmgu/Pth1r+
C57BL/6N-Pth1rtm1a(EUCOMM)Hmgu/Wtsi
decreased bone mineral content J:211773
increased grip strength J:211773
Pth1rtm1a(EUCOMM)Hmgu/Pth1rtm1a(EUCOMM)Hmgu
C57BL/6N-Pth1rtm1a(EUCOMM)Hmgu/Wtsi
abnormal brain morphology J:239583
abnormal ductus venosus valve morphology J:239583
abnormal inferior vena cava valve morphology J:239583
abnormal lens morphology J:239583
abnormal thymus morphology J:239583
abnormal vertebral artery topology J:239583
absent ductus venosus valve J:239583
absent segment of posterior cerebral artery J:239583
anastomosis between internal carotid artery and basilar artery J:239583
blood in lymph vessels J:239583
decreased total retina thickness J:239583
dilated bile duct J:239583
enlarged lymphatic vessel J:239583
enlarged paraumbilical vein J:239583
hemorrhage J:239583
herniated liver J:239583
increased hemangioma incidence J:239583
jugular vein stenosis J:239583
preweaning lethality, complete penetrance J:211773
retropharyngeal edema J:239583
Pth1rtm1Abas/Pth1rtm1Abas
B6.Cg-Pth1rtm1Abas
abnormal blood homeostasis J:113660
abnormal circulating phosphate level J:113660
abnormal osteoblast physiology J:113660
decreased circulating parathyroid hormone level J:113660
increased circulating calcium level J:113660
Pth1rtm1Hmk/Pth1rtm1Hmk
involves: 129X1/SvJ * Black Swiss * C57BL/6
abnormal bone mineralization J:34604
abnormal hyaline cartilage morphology J:34604
abnormal long bone epiphyseal plate proliferative zone J:34604
abnormal neurocranium morphology J:34604
abnormal synchondrosis J:34604
atelectasis J:61316
decreased embryo size J:34604, J:61316
decreased fetal size J:61316
decreased length of long bones J:34604
domed cranium J:34604
embryonic growth retardation J:61316
foramen magnum stenosis J:34604
neonatal lethality, complete penetrance J:61316
perinatal lethality, complete penetrance J:34604
protruding tongue J:34604
respiratory failure J:61316
normal respiratory system phenotype J:61316
short limbs J:34604
short mandible J:34604
short snout J:34604
small lung J:61316
Pth1rtm1Hmk/Pth1rtm1Hmk
involves: 129X1/SvJ * C57BL/6
decreased embryo size J:34604
lethality throughout fetal growth and development, incomplete penetrance J:34604
Pth1rtm1Hmk/Pth1rtm1Hmk
involves: 129X1/SvJ * C57BL/6 * MF1
decreased embryo size J:34604
prenatal lethality, incomplete penetrance J:34604
Pth1rtm1Hmk/Pth1rtm2Hmk
Tg(Bglap2-cre)1Kry/0
involves: 129S4/SvJae * C57BL/6 * FVB
abnormal long bone epiphyseal plate morphology J:99641
increased long bone epiphyseal plate size J:99641
Pth1rtm1Hmk/Pth1rtm3Hmk
involves: 129S4/SvJae * C57BL/6
abnormal limb morphology J:77683
abnormal long bone epiphyseal plate morphology J:77683
abnormal long bone hypertrophic chondrocyte zone J:77683
long tibia J:77683
postnatal growth retardation J:77683
premature chondrocyte differentiation J:77683
Pth1rtm2Hmk/Pth1rtm2Hmk
Tg(Bglap2-cre)1Kry/0
involves: 129S4/SvJae * C57BL/6 * FVB
abnormal long bone epiphyseal plate morphology J:77683
abnormal long bone hypertrophic chondrocyte zone J:77683
Pth1rtm2Hmk/Pth1rtm2Hmk
Tg(Col2a1-cre)1Rsjo/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
abnormal sternum morphology J:77683
chondrodystrophy J:77683
decreased chondrocyte number J:77683
decreased long bone epiphyseal plate size J:77683
Pth1rtm2Hmk/Pth1rtm2Hmk
Tg(Dmp1-cre/ERT2)0022Pdp/0
involves: 129S4/SvJae * C3H * C57BL/6
abnormal trabecular bone morphology J:170229
decreased bone mineral density J:170229
normal skeleton phenotype J:170229
Pth1rtm3Hmk/Pth1rtm3Hmk
involves: 129S4/SvJae * C57BL/6
abnormal long bone epiphyseal plate morphology J:77683
Pth1rtm4Hmk/Pth1rtm4Hmk
involves: 129S4/SvJae * C57BL/6
abnormal skeleton development J:108984

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/18/2019
MGI 6.14
The Jackson Laboratory