Ptgs2tm1.1Fun/Ptgs2tm1.1Fun
involves: 129S6/SvEvTac
|
abnormal kidney cortex morphology |
J:148699
|
|
decreased renal glomerulus number |
J:148699
|
|
glomerulosclerosis |
J:148699
|
|
increased blood urea nitrogen level |
J:148699
|
|
kidney inflammation |
J:148699
|
Ptgs2tm1.1Fun/Ptgs2tm1.1Fun
involves: 129S6/SvEvTac * C57BL/6
|
abnormal kidney cortex morphology |
J:109548
|
|
abnormal renal glomerulus morphology |
J:109548
|
|
decreased prostaglandin level |
J:109548
|
|
glomerulosclerosis |
J:109548
|
|
pale kidney |
J:109548
|
|
reduced female fertility |
J:109548
|
|
small kidney |
J:109548
|
Ptgs2tm1.1Wls/Ptgs2tm1.1Wls
B6.129-Ptgs2tm1.1Wls
|
normal
cardiovascular system phenotype |
J:156331
|
|
impaired febrile response |
J:156331
|
|
increased susceptibility to endotoxin shock |
J:156331
|
|
increased urine prostaglandin level |
J:156331
|
|
normal
renal/urinary system phenotype |
J:156331
|
|
normal
reproductive system phenotype |
J:156331
|
Ptgs2tm1Fun/Ptgs2tm1Fun
involves: 129S6/SvEvTac * C57BL/6
|
abnormal blood coagulation |
J:108957
|
|
abnormal platelet physiology |
J:108957
|
|
abnormal thrombolysis |
J:108957
|
|
decreased prostaglandin level |
J:109548
|
|
decreased susceptibility to induced thrombosis |
J:108957
|
|
decreased urine prostaglandin level |
J:108957
|
|
increased systemic arterial systolic blood pressure |
J:108957
|
Ptgs2tm1Gaf/Ptgs2tm1Gaf
A1cfTg(Myh6-cre/Esr1*)1Jmk/?
involves: 129/Sv * C57BL/6 * FVB/N
|
decreased heart rate |
J:148331
|
|
decreased ventricle muscle contractility |
J:148331
|
|
dilated heart left ventricle |
J:148331
|
|
impaired exercise endurance |
J:148331
|
|
increased myocardial fiber size |
J:148331
|
|
ventricular tachycardia |
J:148331
|
|
weight loss |
J:148331
|
Ptgs2tm1Hahe/Ptgs2tm1Hahe
involves: 129S4/SvJae
|
no abnormal phenotype detected |
J:107615
|
Ptgs2tm1Jed/Ptgs2tm1Jed
B6;129S-Ptgs2tm1Jed/J
|
abnormal stomach pH |
J:103642
|
|
decreased physiological sensitivity to xenobiotic |
J:103642
|
|
pulmonary interstitial fibrosis |
J:68669
|
Ptgs2tm1Jed/Ptgs2tm1Jed
involves: 129S7/SvEvBrd
|
abnormal kidney collecting duct morphology |
J:29974
|
|
abnormal kidney cortex morphology |
J:29974
|
|
abnormal kidney corticomedullary boundary morphology |
J:29974
|
|
abnormal kidney development |
J:29974
|
|
abnormal kidney mesenchyme morphology |
J:29974
|
|
abnormal kidney morphology |
J:29974
|
|
abnormal renal glomerulus morphology |
J:29974
|
|
abnormal renal tubule morphology |
J:29974
|
|
absent corpus luteum |
J:29974
|
|
cardiac fibrosis |
J:29974
|
|
decreased ovulation rate |
J:29974
|
|
female infertility |
J:29974
|
|
normal
hematopoietic system phenotype |
J:29974
|
|
normal
immune system phenotype |
J:29974
|
|
increased blood urea nitrogen level |
J:29974
|
|
increased circulating creatinine level |
J:29974
|
|
kidney corticomedullary cyst |
J:29974
|
|
kidney failure |
J:29974
|
|
kidney medulla hypoplasia |
J:29974
|
|
neonatal lethality, incomplete penetrance |
J:29974
|
|
premature death |
J:29974
|
|
pyelonephritis |
J:29974
|
|
small ovary |
J:29974
|
Ptgs2tm1Jed/Ptgs2tm1Jed
involves: 129S7/SvEvBrd * C57BL/6
|
abnormal decidualization |
J:43609
|
|
abnormal kidney cortex morphology |
J:104002
|
|
abnormal kidney development |
J:104002
|
|
abnormal primary polar body morphology |
J:43609
|
|
abnormal proximal convoluted tubule morphology |
J:104002
|
|
abnormal renal glomerulus morphology |
J:104002,
J:109548,
J:118171
|
|
normal
behavior/neurological phenotype |
J:104002
|
|
normal
cardiovascular system phenotype |
J:104002
|
|
cortical renal glomerulopathies |
J:118171
|
|
decreased kidney weight |
J:104002
|
|
decreased litter size |
J:118171
|
|
decreased prostaglandin level |
J:109548
|
|
decreased renal glomerular filtration rate |
J:104002
|
|
decreased superovulation rate |
J:43609,
J:69034
|
|
decreased vascular permeability |
J:118171
|
|
dilated renal tubule |
J:104002
|
|
failure of embryo implantation |
J:43609
|
|
glomerulosclerosis |
J:104002,
J:109548
|
|
normal
growth/size/body region phenotype |
J:104002
|
|
normal
homeostasis/metabolism phenotype |
J:104002
|
|
impaired fertilization |
J:43609
|
|
increased blood urea nitrogen level |
J:104002,
J:118171
|
|
increased circulating creatinine level |
J:104002
|
|
increased heart weight |
J:104002
|
|
kidney cortex atrophy |
J:109548
|
|
kidney cortex cyst |
J:104002
|
|
kidney cyst |
J:104002
|
|
kidney degeneration |
J:104002
|
|
kidney failure |
J:104002
|
|
pale kidney |
J:109548
|
|
patent ductus arteriosus |
J:109548
|
|
peritoneal inflammation |
J:118171
|
|
premature death |
J:104002
|
|
proximal convoluted tubule brush border loss |
J:104002
|
|
reduced female fertility |
J:109548,
J:118171
|
|
renal glomerulus cyst |
J:104002
|
|
renal glomerulus fibrosis |
J:104002
|
|
renal glomerulus hypertrophy |
J:104002
|
|
renal interstitial fibrosis |
J:104002
|
|
renal tubule atrophy |
J:104002
|
|
renal tubule hypertrophy |
J:104002
|
|
normal
renal/urinary system phenotype |
J:104002
|
|
normal
reproductive system phenotype |
J:69034
|
|
small kidney |
J:109548
|
Ptgs2tm1Jed/Ptgs2tm1Jed
involves: 129S7/SvEvBrd * CD-1
|
abnormal response to infection |
J:120725
|
Ptgs2tm1Unc/Ptgs2+
B6.129P2-Ptgs2tm1Unc
|
decreased cerebral infarct size |
J:67211
|
|
decreased prostaglandin level |
J:67211
|
Ptgs2tm1Unc/Ptgs2+
D1.129P2(B6J)-Ptgs2tm1Unc
|
increased chemical nociceptive threshold |
J:64383
|
Ptgs2tm1Unc/Ptgs2+
D1.129P2-Ptgs2tm1Unc
|
abnormal adipose tissue physiology |
J:102779
|
|
decreased total fat pad weight |
J:102779
|
|
increased body weight |
J:102779
|
|
increased circulating insulin level |
J:102779
|
|
increased circulating leptin level |
J:102779
|
|
increased prostaglandin level |
J:102779
|
|
increased susceptibility to diet-induced obesity |
J:102779
|
Ptgs2tm1Unc/Ptgs2+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6
|
abnormal osteoclast differentiation |
J:124756
|
|
decreased prostaglandin level |
J:124756
|
Ptgs2tm1Unc/Ptgs2+
involves: 129P2/OlaHsd * C57BL/6J
|
impaired febrile response |
J:54450
|
|
increased systemic arterial systolic blood pressure |
J:155373
|
Ptgs2tm1Unc/Ptgs2tm1Unc
B6.129P2-Ptgs2tm1Unc
|
abnormal choriocapillaris morphology |
J:281382
|
|
abnormal class switch recombination |
J:140698
|
|
abnormal drinking behavior |
J:125586
|
|
abnormal memory B cell differentiation |
J:140698
|
|
abnormal nociception after inflammation |
J:110716
|
|
abnormal response to CNS ischemic injury |
J:67211
|
|
abnormal response to infection |
J:140698
|
|
abnormal response/metabolism to endogenous compounds |
J:125586
|
|
allodynia |
J:110716
|
|
decreased cerebral infarct size |
J:67211
|
|
decreased IgG1 level |
J:140698
|
|
decreased IgG2a level |
J:140698
|
|
decreased IgG3 level |
J:140698
|
|
decreased prostaglandin level |
J:67211
|
|
decreased susceptibility to induced arthritis |
J:110716
|
|
decreased susceptibility to neuronal excitotoxicity |
J:67211
|
|
increased IgM level |
J:140698
|
|
increased thermal nociceptive threshold |
J:110716
|
Ptgs2tm1Unc/Ptgs2tm1Unc
B6;129P2-Ptgs2tm1Unc/Tac
|
abnormal bone healing |
J:112346
|
|
abnormal endochondral bone ossification |
J:112346
|
|
abnormal inhibitory postsynaptic currents |
J:141610
|
|
abnormal response to injury |
J:107751
|
|
decreased prostaglandin level |
J:141610
|
|
impaired skeletal muscle regeneration |
J:107751
|
|
increased susceptibility to neuronal excitotoxicity |
J:141610
|
|
increased susceptibility to pharmacologically induced seizures |
J:141610
|
|
increased susceptibility to xenobiotic induced morbidity/mortality |
J:141610
|
|
renal glomerulus hypertrophy |
J:156331
|
|
tonic-clonic seizures |
J:141610
|
Ptgs2tm1Unc/Ptgs2tm1Unc
D1.129P2(B6J)-Ptgs2tm1Unc
|
abnormal kidney mesenchyme morphology |
J:102777
|
|
abnormal kidney morphology |
J:64383
|
|
abnormal renal glomerulus morphology |
J:102777
|
|
normal
behavior/neurological phenotype |
J:64383
|
|
decreased aggression |
J:64383
|
|
decreased hematocrit |
J:102777
|
|
decreased kidney weight |
J:102777
|
|
female infertility |
J:64383
|
|
granular kidney |
J:102777
|
|
increased blood urea nitrogen level |
J:102777
|
|
increased circulating creatinine level |
J:102777
|
|
normal
mortality/aging |
J:64383
|
|
pale kidney |
J:102777
|
|
postnatal lethality |
J:102777
|
|
renal glomerulus cyst |
J:102777
|
|
renal glomerulus hypertrophy |
J:102777
|
|
renal interstitial fibrosis |
J:102777
|
|
small kidney |
J:102777
|
Ptgs2tm1Unc/Ptgs2tm1Unc
D1.129P2-Ptgs2tm1Unc
|
decreased prostaglandin level |
J:102779
|
Ptgs2tm1Unc/Ptgs2tm1Unc
involves: 129/Sv * 129P2/OlaHsd * C57BL/6
|
abnormal osteoclast differentiation |
J:124756
|
|
decreased platelet calcium level |
J:124756
|
|
decreased prostaglandin level |
J:124756
|
Ptgs2tm1Unc/Ptgs2tm1Unc
involves: 129P2/OlaHsd
|
normal
digestive/alimentary phenotype |
J:108679
|
Ptgs2tm1Unc/Ptgs2tm1Unc
involves: 129P2/OlaHsd * C57BL/6
|
abnormal colon morphology |
J:60668
|
|
abnormal enzyme/coenzyme level |
J:108054
|
|
abnormal keratinocyte differentiation |
J:117986
|
|
abnormal kidney cortex morphology |
J:104002
|
|
abnormal kidney development |
J:104002
|
|
abnormal proximal convoluted tubule morphology |
J:104002
|
|
abnormal renal glomerulus morphology |
J:104002
|
|
abnormal response of heart to induced stress |
J:103388
|
|
anemia |
J:60668
|
|
normal
behavior/neurological phenotype |
J:104002
|
|
normal
cardiovascular system phenotype |
J:104002
|
|
decreased hematocrit |
J:60668
|
|
decreased incidence of tumors by chemical induction |
J:158426
|
|
decreased kidney weight |
J:104002
|
|
decreased lactate dehydrogenase level |
J:108054
|
|
decreased prostaglandin level |
J:60668,
J:117986
|
|
decreased renal glomerular filtration rate |
J:104002
|
|
decreased susceptibility to endotoxin shock |
J:75611
|
|
decreased susceptibility to induced pancreatitis |
J:108054
|
|
decreased susceptibility to injury |
J:108054
|
|
dilated renal tubule |
J:104002
|
|
enlarged spleen |
J:60668
|
|
glomerulosclerosis |
J:104002
|
|
normal
growth/size/body region phenotype |
J:104002
|
|
normal
homeostasis/metabolism phenotype |
J:104002
|
|
increased blood urea nitrogen level |
J:104002
|
|
increased circulating creatinine level |
J:104002
|
|
increased heart weight |
J:104002
|
|
increased incidence of induced tumors |
J:158426
|
|
increased leukocyte cell number |
J:60668
|
|
increased susceptibility to induced colitis |
J:60668,
J:158426
|
|
increased susceptibility to xenobiotic induced morbidity/mortality |
J:60668,
J:158426
|
|
increased tumor necrosis factor secretion |
J:108054
|
|
kidney cortex cyst |
J:104002
|
|
kidney cyst |
J:104002
|
|
kidney degeneration |
J:104002
|
|
kidney failure |
J:104002
|
|
normal
muscle phenotype |
J:146321
|
|
pancreas necrosis |
J:108054
|
|
peritoneal inflammation |
J:60668
|
|
premature death |
J:104002
|
|
proximal convoluted tubule brush border loss |
J:104002
|
|
renal glomerulus cyst |
J:104002
|
|
renal glomerulus fibrosis |
J:104002
|
|
renal glomerulus hypertrophy |
J:104002
|
|
renal interstitial fibrosis |
J:104002
|
|
renal tubule atrophy |
J:104002
|
|
renal tubule hypertrophy |
J:104002
|
|
normal
renal/urinary system phenotype |
J:104002
|
|
weight loss |
J:60668
|
Ptgs2tm1Unc/Ptgs2tm1Unc
involves: 129P2/OlaHsd * C57BL/6 * DBA/1
|
abnormal wound healing |
J:126734
|
Ptgs2tm1Unc/Ptgs2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
|
abnormal corpus luteum morphology |
J:55145
|
|
abnormal cumulus expansion |
J:55145
|
|
abnormal induced retina neovascularization |
J:109021
|
|
abnormal intestinal mucosa morphology |
J:29510
|
|
abnormal kidney capsule morphology |
J:29510
|
|
abnormal kidney development |
J:29510
|
|
abnormal kidney morphology |
J:29510
|
|
abnormal kidney papilla morphology |
J:29510
|
|
abnormal lipid homeostasis |
J:121680
|
|
abnormal liver morphology |
J:67208
|
|
abnormal macrophage physiology |
J:29510
|
|
abnormal mesenteric lymph node morphology |
J:29510
|
|
abnormal nephrogenic zone morphology |
J:29510
|
|
abnormal reproductive system physiology |
J:29510
|
|
abnormal thrombosis |
J:109021
|
|
decreased nephron number |
J:29510
|
|
decreased prostaglandin level |
J:55145,
J:109021
|
|
decreased renal glomerulus number |
J:29510
|
|
decreased superovulation rate |
J:55145
|
|
decreased survivor rate |
J:67208
|
|
dilated renal tubule |
J:29510
|
|
failure of superovulation |
J:55145
|
|
female infertility |
J:55145
|
|
glomerulosclerosis |
J:29510
|
|
normal
homeostasis/metabolism phenotype |
J:55145
|
|
normal
immune system phenotype |
J:29510
|
|
impaired febrile response |
J:54450
|
|
impaired granulosa cell differentiation |
J:55145
|
|
increased circulating follicle stimulating hormone level |
J:55145
|
|
increased circulating luteinizing hormone level |
J:55145
|
|
increased systemic arterial blood pressure |
J:155373
|
|
increased systemic arterial diastolic blood pressure |
J:155373
|
|
increased systemic arterial systolic blood pressure |
J:155373
|
|
intestinal edema |
J:29510
|
|
kidney cortex atrophy |
J:29510
|
|
neonatal lethality, incomplete penetrance |
J:67208
|
|
nephrocalcinosis |
J:29510
|
|
pale kidney |
J:29510,
J:55145
|
|
patent ductus arteriosus |
J:67208
|
|
peritoneal inflammation |
J:29510
|
|
postnatal lethality, incomplete penetrance |
J:67208
|
|
premature death |
J:29510
|
|
renal cast |
J:29510
|
|
renal glomerulus hypertrophy |
J:29510
|
|
renal interstitial fibrosis |
J:29510
|
|
renal tubule atrophy |
J:29510
|
|
small kidney |
J:29510
|
|
spleen hyperplasia |
J:29510
|
|
tubulointerstitial nephritis |
J:29510
|
Ptgs2tm1Unc/Ptgs2tm2.1Hahe
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
increased susceptibility to induced colitis |
J:158426
|
|
increased susceptibility to xenobiotic induced morbidity/mortality |
J:158426
|
|
normal
neoplasm |
J:158426
|
Ptgs2tm1Wlf/Ptgs2tm1Wlf
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL
|
abnormal chemical nociception |
J:146193
|
|
abnormal nociception after inflammation |
J:146193
|
|
normal
homeostasis/metabolism phenotype |
J:146193
|
Ptgs2tm3Fun/Ptgs2tm3Fun
involves: 129S6/SvEvTac * C57BL/6J
|
abnormal renal glomerulus morphology |
J:148699
|
|
abnormal renal tubule morphology |
J:148699
|
|
abnormal urine homeostasis |
J:148699
|
|
normal
cardiovascular system phenotype |
J:148699
|
|
increased blood urea nitrogen level |
J:148699
|
|
increased platelet aggregation |
J:148699
|
|
increased susceptibility to induced thrombosis |
J:148699
|
|
normal
renal/urinary system phenotype |
J:148699
|
Tg(K5-Ptgs2)19Kmd/0
involves: NMRI
|
abnormal coat appearance |
J:70039
|
|
abnormal dermal layer morphology |
J:70039
|
|
abnormal hair follicle development |
J:70039
|
|
abnormal hair follicle orientation |
J:70039
|
|
abnormal nail morphology |
J:70039
|
|
alopecia |
J:70039
|
|
coarse hair |
J:70039
|
|
decreased hair follicle number |
J:70039
|
|
epidermal hyperplasia |
J:70039
|
|
greasy coat |
J:70039
|
|
hyperkeratosis |
J:70039
|
|
increased incidence of tumors by chemical induction |
J:79071
|
|
increased prostaglandin level |
J:70039
|
|
increased sebaceous gland adenoma incidence |
J:79071
|
|
increased skin papilloma incidence |
J:79071
|
|
increased squamous cell carcinoma incidence |
J:79071
|
|
long toenails |
J:70039
|
|
sebaceous gland hyperplasia |
J:70039
|
|
sparse hair |
J:70039
|
|
thin skin |
J:70039
|
Tg(K5-Ptgs2)667Kmd/0
involves: NMRI
|
abnormal coat appearance |
J:70039
|
|
abnormal coat/ hair morphology |
J:70039
|
|
abnormal dermal layer morphology |
J:70039
|
|
abnormal hair follicle development |
J:70039
|
|
abnormal hair follicle orientation |
J:70039
|
|
abnormal nail morphology |
J:70039
|
|
alopecia |
J:70039
|
|
coarse hair |
J:70039
|
|
decreased hair follicle number |
J:70039
|
|
epidermal hyperplasia |
J:70039
|
|
hyperkeratosis |
J:70039
|
|
increased incidence of tumors by chemical induction |
J:79071
|
|
increased prostaglandin level |
J:70039
|
|
increased sebaceous gland adenoma incidence |
J:79071
|
|
increased skin papilloma incidence |
J:79071
|
|
increased squamous cell carcinoma incidence |
J:79071
|
|
long toenails |
J:70039
|
|
premature death |
J:79071
|
|
sebaceous gland hyperplasia |
J:70039
|
|
sparse hair |
J:70039
|
|
thin skin |
J:70039
|
Tg(K5-Ptgs2)675Kmd/0
involves: NMRI
|
abnormal coat appearance |
J:70039
|
|
abnormal coat/ hair morphology |
J:70039
|
|
abnormal dermal layer morphology |
J:70039
|
|
abnormal hair follicle development |
J:70039
|
|
abnormal hair follicle orientation |
J:70039
|
|
abnormal nail morphology |
J:70039
|
|
alopecia |
J:70039
|
|
coarse hair |
J:70039
|
|
decreased hair follicle number |
J:70039
|
|
epidermal hyperplasia |
J:70039
|
|
greasy coat |
J:70039
|
|
hyperkeratosis |
J:70039
|
|
increased prostaglandin level |
J:70039
|
|
long toenails |
J:70039
|
|
premature death |
J:70039
|
|
sebaceous gland hyperplasia |
J:70039
|
|
sparse hair |
J:70039
|
|
thin skin |
J:70039
|
Tg(K5-Ptgs2)675Kmd/Tg(K5-Ptgs2)675Kmd
involves: NMRI
|
abnormal hair cycle |
J:85979
|
|
abnormal hair follicle morphology |
J:85979
|
|
alopecia |
J:85979
|
|
sebaceous gland hyperplasia |
J:85979
|
|
sparse hair |
J:85979
|
Tg(Nphs1-Ptgs2)14Rhrs/0
involves: C57BL/6 * DBA/2
|
abnormal glomerular mesangium morphology |
J:148158,
J:179350
|
|
abnormal podocyte morphology |
J:179350
|
|
albuminuria |
J:148158,
J:179350
|
|
increased renal glomerulus basement membrane thickness |
J:179350
|
|
increased susceptibility to injury |
J:148158
|
|
podocyte foot process effacement |
J:148158,
J:179350
|
Excel File
Analysis Tools