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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ptger2
prostaglandin E receptor 2 (subtype EP2)
MGI:97794
36 phenotypes from 5 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ptger2tm1.1Kand/Ptger2tm1.1Kand
Tg(ITGAM-cre)2781Gkl/0
involves: C57BL/6 * CBA
abnormal microglial cell physiology J:202677
decreased physiological sensitivity to xenobiotic J:202677
decreased susceptibility to endotoxin shock J:202677
increased physiological sensitivity to xenobiotic J:202677
Ptger2tm1Brey/Ptger2tm1Brey
B6.129S6-Ptger2tm1Brey
abnormal response to injury J:87388
abnormal spatial learning J:143076
increased cerebral infarction size J:87388
Ptger2tm1Brey/Ptger2tm1Brey
C.129S6-Ptger2tm1Brey
abnormal excitatory postsynaptic potential J:143076
abnormal microglial cell physiology J:97062
reduced long term potentiation J:143076
Ptger2tm1Brey/Ptger2tm1Brey
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6)
abnormal circulating calcium level J:77679
Ptger2tm1Brey/Ptger2tm1Brey
involves: 129S6/SvEvTac
abnormal vasodilation J:78902
decreased incidence of tumors by chemical induction J:116015
decreased tumor growth/size J:116015
normal homeostasis/metabolism phenotype J:116015
increased vasoconstriction J:78902
Ptger2tm1Brey/Ptger2tm1Brey
involves: 129S6/SvEvTac * BALB/c
abnormal nervous system physiology J:164638
abnormal response to infection J:164638
Ptger2tm1Brey/Ptger2tm1Brey
involves: 129S6/SvEvTac * C57BL/6
abnormal airway responsiveness J:103373
abnormal response to infection J:120725
abnormal superovulation J:69034
abnormal vasodilation J:53646
decreased litter size J:53646
increased systemic arterial blood pressure J:53646
reduced female fertility J:53646
normal reproductive system phenotype J:69034
Ptger2tm1Rsz/Ptger2tm1Rsz
involves: 129S6/SvEvTac * C57BL/6
abnormal osteoclast differentiation J:77408
Ptger2tm1Sna/Ptger2tm1Sna
B6.129P2-Ptger2tm1Sna
normal immune system phenotype J:197334
Ptger2tm1Sna/Ptger2tm1Sna
involves: 129P2/OlaHsd * C57BL/6
abnormal cumulus expansion J:70534
abnormal oocyte morphology J:57482
absent cumulus expansion J:57482
decreased corpora lutea number J:57482
decreased litter size J:57482
decreased ovulation rate J:57482
normal homeostasis/metabolism phenotype J:70534
impaired fertilization J:57482
normal mortality/aging J:57482
reduced female fertility J:57482
Ptger2tm2Bhk/Ptger2tm2Bhk
involves: 129P2/OlaHsd
normal cardiovascular system phenotype J:77409
normal renal/urinary system phenotype J:77409
Ptger2tm2Bhk/Ptger2tm2Bhk
involves: 129P2/OlaHsd * 129S/SvEv
abnormal renin activity J:55713
decreased litter size J:55713
hypotension J:55713
normal immune system phenotype J:78964
impaired fertilization J:55713
reduced female fertility J:55713

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory