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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ptbp1
polypyrimidine tract binding protein 1
MGI:97791
27 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ptbp1tm1Msol/Ptbp1tm1Msol
B6J.129-Ptbp1tm1Msol
abnormal ectoplacental cone morphology J:223915
abnormal endoderm development J:223915
abnormal gastrulation J:223915
abnormal Reichert's membrane morphology J:223915
abnormal visceral yolk sac morphology J:223915
absent blastocoele J:223915
decreased cell proliferation J:223915
decreased embryo size J:223915
embryonic growth retardation J:223915
embryonic lethality during organogenesis, complete penetrance J:223915
increased apoptosis J:223915
Ptbp1tm1Nobu/Ptbp1tm1Nobu
involves: 129P2/OlaHsd
embryonic lethality between implantation and somite formation, complete penetrance J:213626
Ptbp1tm1Nobu/Ptbp1tm2Nobu
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd
abnormal brain ependyma motile cilium morphology J:213479
abnormal telencephalon morphology J:213479
dilated lateral ventricle J:213479
hydrocephaly J:213479
Ptbp1tm1Nobu/Ptbp1tm2Nobu
Tg(Nes-cre)1Sasa/0
involves: 129P2/OlaHsd
abnormal brain ependyma morphology J:213479
abnormal lateral ventricle morphology J:213479
abnormal nervous system development J:213479
abnormal neuronal stem cell morphology J:213479
dilated lateral ventricle J:213479
domed cranium J:213479
ectopic neuron J:213479
increased astrocyte number J:213479
normal nervous system phenotype J:213479
non-obstructive hydrocephaly J:213479
premature death J:213479
premature neuronal precursor differentiation J:213479
Ptbp1tm1Nobu/Ptbp1tm2Nobu
Tg(Nes-cre/ERT2)#Kag/0
involves: 129P2/OlaHsd * C57BL/6
normal nervous system phenotype J:213479

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory