Ctsa Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctsa
cathepsin A
MGI:97748

60 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ctsa^tm1.1Avps/Ctsa^tm1.1Avps involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal blood vessel elastic tissue morphology	J:153297
	abnormal cutaneous elastic fiber morphology	J:153297
	abnormal pulmonary elastic fiber morphology	J:153297
	abnormal response/metabolism to endogenous compounds	J:153297
	normal growth/size/body region phenotype	J:153297
	increased fluid intake	J:153297
	increased mean systemic arterial blood pressure	J:153297
	increased systemic arterial diastolic blood pressure	J:153297
	increased systemic arterial systolic blood pressure	J:153297
	normal mortality/aging	J:153297
	overexpanded pulmonary alveolus	J:153297
	polyuria	J:153297
	normal reproductive system phenotype	J:153297
Ctsa^tm1Adz/Ctsa^tm1Adz either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/NJ)	abnormal lysosome morphology	J:29674
	ataxia	J:29674
	decreased body size	J:29674
	disheveled coat	J:29674
	edema	J:29674
	enlarged liver	J:29674
	enlarged spleen	J:29674
	flat face	J:29674
	premature death	J:29674
	tremors	J:29674
Ctsa^tm1Avps/Ctsa^tm1Avps involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	normal growth/size/body region phenotype	J:153297
	normal mortality/aging	J:153297
	normal reproductive system phenotype	J:153297
Ctsa^{tm2b(EUCOMM)Hmgu}/Ctsa^{tm2b(EUCOMM)Hmgu} C57BL/6N-Ctsa^{tm2b(EUCOMM)Hmgu}/H	abnormal forelimb morphology	J:211773
	abnormal freezing behavior	J:211773
	abnormal gait	J:211773
	abnormal head morphology	J:211773
	abnormal hindlimb morphology	J:211773
	abnormal locomotor behavior	J:211773
	abnormal startle reflex	J:211773
	decreased circulating calcium level	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased circulating triglyceride level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased exploration in new environment	J:211773
	decreased heart rate	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased locomotor activity	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	enlarged spleen	J:211773
	impaired cued conditioning behavior	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating bilirubin level	J:211773
	increased circulating iron level	J:211773
	increased freezing behavior	J:211773
	increased heart weight	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
	increased monocyte cell number	J:211773
	increased spleen weight	J:211773
	narrow eye opening	J:211773
	prolonged RR interval	J:211773
	thrombocytopenia	J:211773
	tremors	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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