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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Plcb1
phospholipase C, beta 1
MGI:97613
24 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Plcb1Tg(LGB)56Mbal/Plcb1Tg(LGB)56Mbal
involves: C57BL/6 * CBA
abnormal brain size J:93076
abnormal long bone morphology J:93076
decreased body length J:93076
decreased body weight J:93076
disproportionate dwarf J:93076
enlarged cranium J:93076
increased cranium width J:93076
increased kidney weight J:93076
increased testis weight J:93076
kyphosis J:93076
postnatal growth retardation J:93076
postnatal lethality J:93076
reduced female fertility J:93076
reduced male fertility J:93076
Plcb1tm1Hssh/Plcb1tm1Hssh
involves: 129 * C57BL/6J
abnormal excitatory postsynaptic currents J:159855
Plcb1tm1Hssh/Plcb1tm1Hssh
involves: 129/Sv * C57BL/6
abnormal spatial learning J:151070
decreased prepulse inhibition J:151070
decreased startle reflex J:151070
hyperactivity J:151070
Plcb1tm1Hssh/Plcb1tm1Hssh
Not Specified
convulsive seizures J:43077
decreased body size J:43077
increased susceptibility to pharmacologically induced seizures J:43077
lethality at weaning, incomplete penetrance J:43077
loss of hippocampal neurons J:43077

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory