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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Plat
plasminogen activator, tissue
MGI:97610
47 phenotypes from 2 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Plattm1.1(KOMP)Vlcg/Plattm1.1(KOMP)Vlcg
C57BL/6N-Plattm1.1(KOMP)Vlcg/Ucd
abnormal heart morphology J:211773
abnormal testis morphology J:211773
enlarged heart J:211773
small testis J:211773
Plattm1Mlg/Plattm1Mlg
B6.129S2-Plattm1Mlg/J
abnormal susceptibility to Coronaviridae infection J:288556
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:288556
Plattm1Mlg/Plattm1Mlg
B6.Cg-Plattm1Mlg
abnormal active avoidance behavior J:89431
abnormal acute phase protein level J:75303
abnormal contextual conditioning behavior J:89431
abnormal cued conditioning behavior J:89431
abnormal cytokine level J:75303
abnormal motor learning J:84875
absent long-term depression J:89431
arthritis J:75303
normal behavior/neurological phenotype J:89431
chronic joint inflammation J:75303
decreased anxiety-related response J:81694, J:94733
decreased dopamine level J:88913
decreased exploration in new environment J:89431
decreased vertical activity J:89431
impaired behavioral response to morphine J:88913
impaired conditioned place preference behavior J:88913
impaired synaptic plasticity J:81694, J:94733
increased circulating corticosterone level J:81694, J:94733
joint swelling J:75303
normal muscle phenotype J:68083
reduced long-term potentiation J:89431
reduced thrombolysis J:64220
Plattm1Mlg/Plattm1Mlg
involves: 129S2/SvPas
abnormal microglial cell physiology J:144185
abnormal response to CNS ischemic injury J:144185
Plattm1Mlg/Plattm1Mlg
involves: 129S2/SvPas * C57BL/6
abnormal acute phase protein level J:63134, J:82604
cardiac interstitial fibrosis J:95236
decreased cerebral infarct size J:55243
decreased retina apoptosis J:93533
decreased susceptibility to induced choroidal neovascularization J:82604
decreased susceptibility to induced retina damage J:93533
decreased ventricle muscle contractility J:95236
normal growth/size/body region phenotype J:17427
heart left ventricle hypertrophy J:95236
normal immune system phenotype J:17427
increased macrophage cell number J:63134
increased susceptibility to induced thrombosis J:17427
intracerebral hemorrhage J:89052
normal mortality/aging J:17427
pulmonary alveolar hemorrhage J:63134
pulmonary interstitial fibrosis J:63134
reduced thrombolysis J:17427
normal reproductive system phenotype J:17427
Plattm1Mlg/Plattm1Mlg
involves: 129S2/SvPas * C57BL/6J
decreased angiogenesis J:108675

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory