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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pkd1
polycystin 1, transient receptor poteintial channel interacting
MGI:97603
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Gpsm1tm1.1Lajb/Gpsm1+
Pkd1tm1.1Fqi/Pkd1tm1.1Fqi
involves: 129S6/SvEvTac
enlarged kidney J:193175
increased blood urea nitrogen level J:193175
polycystic kidney J:193175
Gpsm1tm1.1Lajb/Gpsm1tm1.1Lajb
Pkd1tm1.1Fqi/Pkd1tm1.1Fqi
involves: 129S6/SvEvTac
abnormal kidney physiology J:193175
enlarged kidney J:193175
increased blood urea nitrogen level J:193175
increased circulating creatinine level J:193175
polycystic kidney J:193175
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Tg(Cdh16-cre)91Igr/0
involves: 129 * 129S4/SvJae * C57BL/6 * ICR
decreased blood urea nitrogen level J:244067
normal renal/urinary system phenotype J:244067
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd1tm1.1Pcha/Pkd1tm2Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * 129S4/SvJae * C57BL/6 * ICR
abnormal peroxisome morphology J:244067
abnormal redox activity J:244067
decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
decreased kidney weight J:244067
increased fatty acid oxidation J:244067
kidney cysts J:244067
normal renal/urinary system phenotype J:244067
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd1tm2Som/Pkd1tm2Som
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJae * C57BL/6 * ICR
decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
decreased kidney weight J:244067
premature death J:244067
Nek8jck/Nek8+
Pkd1tm1Bdgz/Pkd1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
kidney cysts J:130086
Pkd1tm1.1Pcha/Pkd1+
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * SJL
increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm1Som/Pkd2+
involves: 129 * C57BL/6J * SJL
increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * SJL
increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
premature death J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm2Som/Pkd2+
involves: 129 * C57BL/6J * SJL
increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pparatm1Gonz/Pparatm1Gonz
involves: 129 * 129S4/SvJae * C57BL/6
enlarged kidney J:244067
increased kidney cell proliferation J:244067
polycystic kidney J:244067
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Tg(Cdh16-cre)91Igr/0
involves: 129 * 129S4/SvJae * C57BL/6 * ICR
increased blood urea nitrogen level J:244067
polycystic kidney J:244067
renal fibrosis J:244067
Pkd1tm1Ggg/Pkd1+
Pkhd1tm1.1Ggg/Pkhd1tm1.1Ggg
involves: 129S/SvEv * 129S4/SvJae * C57BL/6
abnormal liver morphology J:125113
dilated kidney collecting duct J:125113
enlarged kidney J:125113
kidney cysts J:125113
liver cysts J:125113
pancreas cysts J:125113
perinatal lethality, incomplete penetrance J:125113
postnatal growth retardation J:125113
premature death J:125113
Pkd1tm1Som/Pkd1+
Pkd2tm2Som/Pkd2+
involves: 129/Sv * C57BL/6 * SJL
kidney cysts J:78422
liver cysts J:78422
Pkd1tm1Som/Pkd1+
Prkcshtm1Som/Prkcshtm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL
abnormal loop of Henle ascending limb thick segment morphology J:188763
dilated kidney collecting duct J:188763
increased blood urea nitrogen level J:188763
increased kidney apoptosis J:188763
increased kidney cell proliferation J:188763
increased kidney weight J:188763
kidney cysts J:188763
Pkd1tm1Som/Pkd1+
Sec63tm1Som/Sec63tm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL
abnormal loop of Henle ascending limb thick segment morphology J:188763
dilated kidney collecting duct J:188763
increased blood urea nitrogen level J:188763
increased kidney apoptosis J:188763
increased kidney cell proliferation J:188763
increased kidney weight J:188763
kidney cysts J:188763

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory