Prkch Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkch
protein kinase C, eta
MGI:97600

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Prkch^tm1.2Gasc/Prkch^tm1.2Gasc Prkcq^tm1Litt/Prkcq^tm1Litt involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	abnormal positive T cell selection	J:186080
	decreased CD4-positive, alpha-beta T cell number	J:186080
	decreased CD8-positive, alpha-beta T cell number	J:186080
	decreased DN1 thymic pro-T cell number	J:186080
	decreased DN4 thymocyte number	J:186080
	decreased double-negative T cell number	J:186080
	decreased double-positive T cell number	J:186080
	decreased T cell proliferation	J:186080
	normal immune system phenotype	J:186080

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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