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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pax6
paired box 6
MGI:97490
188 phenotypes from 42 alleles in 45 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Pax61Jrt/Pax6+
C3.B6-Pax61Jrt 		abnormal iris morphology J:86523
abnormal lens morphology J:86523
abnormal retina ganglion layer morphology J:86523
anophthalmia J:86523
anterior iris synechia J:86523
corneal opacity J:86523
microphthalmia J:86523
Pax62Neu/Pax6+
involves: 102 * C3H 		abnormal pupil morphology J:73625
anterior iris synechia J:63651
anterior polar cataract J:63651
microphthalmia J:63651, J:73625
Pax62Neu/Pax62Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax63Neu/Pax6+
either: (involves: 102 * C3H) or (involves: C3H) 		anterior iris synechia J:63651
anterior polar cataract J:21950
cataract J:63651
corneal opacity J:21950
fused cornea and lens J:21950
irregularly shaped pupil J:73625
microphthalmia J:63651, J:73625
Pax63Neu/Pax6+
involves: 102 * C3H 		abnormal cortical ventricular zone morphology J:151902
abnormal forebrain morphology J:151902
abnormal postnatal subventricular zone morphology J:151902
corneal opacity J:151902
eye opacity J:151902
fused cornea and lens J:151902
microphthalmia J:151902
telencephalon hypoplasia J:151902
Pax63Neu/Pax63Neu
either: (involves: 102 * C3H) or (involves: C3H) 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax64Neu/Pax6+
either: (involves: 102 * C3H) or (involves: C3H) 		abnormal iris morphology J:73625
anterior iris synechia J:63651
anterior polar cataract J:73625
cataract J:63651
irregularly shaped pupil J:73625
microphthalmia J:63651, J:73625
Pax64Neu/Pax64Neu
either: (involves: 102 * C3H) or (involves: C3H) 		abnormal craniofacial development J:73625
abnormal lateral nasal prominence morphology J:73625
abnormal medial nasal prominence morphology J:73625
anophthalmia J:73625
postnatal lethality, complete penetrance J:73625
Pax64Neu/Pax64Neu
involves: C3HeB/FeJ 		abnormal telencephalon morphology J:94457
Pax65Neu/Pax6+
involves: 102 * C3H 		abnormal pupil morphology J:73625
anterior iris synechia J:63651
anterior polar cataract J:63651
microphthalmia J:63651, J:73625
Pax65Neu/Pax65Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax66Neu/Pax6+
involves: 102 * C3H 		abnormal pupil morphology J:73625
anterior iris synechia J:63651
anterior polar cataract J:63651
microphthalmia J:63651, J:73625
Pax66Neu/Pax66Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax67Neu/Pax6+
involves: 102 * C3H 		abnormal iris morphology J:73625
anterior iris synechia J:63651, J:73625
anterior polar cataract J:63651
cataract J:73625
irregularly shaped pupil J:73625
microphthalmia J:63651, J:73625
Pax67Neu/Pax67Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax68Neu/Pax6+
involves: 102 * C3H 		abnormal pupil morphology J:73625
microphthalmia J:73625
Pax68Neu/Pax68Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax69Neu/Pax6+
involves: 102 * C3H 		abnormal pupil morphology J:73625
microphthalmia J:73625
Pax69Neu/Pax69Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax610Neu/Pax6+
involves: 102 * C3H 		abnormal pupil morphology J:73625
microphthalmia J:73625
Pax610Neu/Pax610Neu
involves: 102 * C3H 		abnormal craniofacial morphology J:73625
anophthalmia J:73625
Pax6132-14Neu/Pax6+
C3.Cg-Pax6132-14Neu 		abnormal cornea morphology J:40665
abnormal corneal endothelium morphology J:40665
abnormal corneal stroma morphology J:40665
abnormal lens morphology J:40665
abnormal lens vesicle development J:40665
anterior polar cataract J:40665
fused cornea and lens J:40665
Pax6132-14Neu/Pax6+
involves: 101 * C3H 		abnormal lens vesicle development J:6686
cataract J:6686
fused cornea and lens J:6686
Pax6132-14Neu/Pax6132-14Neu
C3.Cg-Pax6132-14Neu 		abnormal corneal stroma morphology J:40665
abnormal eye anterior chamber morphology J:40665
abnormal lens morphology J:40665
abnormal vitreous body morphology J:40665
coloboma J:40665
fused cornea and lens J:40665
microphthalmia J:40665
Pax6132-14Neu/Pax6132-14Neu
involves: 101 * C3H 		anophthalmia J:6686
Pax6ADD4802/Pax6+
involves: C3H * T STOCK 		cataract J:103785
corneal opacity J:103785
fused cornea and lens J:103785
microphthalmia J:103785
Pax6Aey80/Pax6+
C3HeB/FeJ-Pax6Aey80 		abnormal eye morphology J:196657
abnormal eye size J:196657
blindness J:196657
corneal-lenticular stalk J:196657
microphthalmia J:196657
small lens J:196657
normal vision/eye phenotype J:196657
Pax6Aey80/Pax6Aey80
C3HeB/FeJ-Pax6Aey80 		anophthalmia J:196657
perinatal lethality, complete penetrance J:196657
Pax6Coop/Pax6+
C3.D2-Pax6Coop 		abnormal iris morphology J:66649
corneal opacity J:66649
microphthalmia J:66649
Pax6Coop/Pax6Coop
C3.D2-Pax6Coop 		absent external nares J:66649
anophthalmia J:66649
prenatal lethality, complete penetrance J:66649
Pax6em1(IMPC)Mbp/Pax6+
C57BL/6N-Pax6em1(IMPC)Mbp/MbpMmucd 		abnormal brain morphology J:211773
abnormal eye morphology J:211773
abnormal liver morphology J:211773
abnormal placenta morphology J:211773
anophthalmia J:211773
corneal opacity J:211773
corneal vascularization J:211773
hyperactivity J:211773
microphthalmia J:211773
small liver J:211773
Pax6em1(IMPC)Mbp/Pax6em1(IMPC)Mbp
C57BL/6N-Pax6em1(IMPC)Mbp/MbpMmucd 		abnormal craniofacial morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
anophthalmia J:211773
cleft palate J:211773
facial cleft J:211773
preweaning lethality, complete penetrance J:211773
Pax6Leca1/Pax6Leca1
involves: BALB/cAnN * C3H/HeN 		abnormal eye morphology J:75964
fused cornea and lens J:75964
microphthalmia J:75964
Pax6Leca2/Pax6Leca2
involves: BALB/cAnN * C3H/HeN 		abnormal eye morphology J:75964
fused cornea and lens J:75964
microphthalmia J:75964
Pax6Leca3/Pax6Leca3
involves: BALB/cAnN * C3H/HeN 		abnormal eye morphology J:75964
fused cornea and lens J:75964
microphthalmia J:75964
Pax6Leca4/Pax6Leca4
involves: BALB/cAnN * C3H/HeN 		abnormal eye morphology J:75964
fused cornea and lens J:75964
microphthalmia J:75964
Pax6m1Lsli/Pax6+
involves: C3H/HeJ * C57BL/6J 		abnormal hormone level J:146325
abnormal pancreas morphology J:146325
decreased adrenocorticotropin level J:146325
impaired glucose tolerance J:146325
Pax6Mhdaaey11/Pax6Mhdaaey11
C3HeB/FeJ-Pax6Mhdaaey11 		cataract J:103785
corneal opacity J:103785
corneal-lenticular stalk J:103785
microphthalmia J:103785
Pax6Mhdaaey18/Pax6+
C3HeB/FeJ-Pax6Mhdaaey18 		cataract J:103785
corneal opacity J:103785
corneal-lenticular stalk J:103785
microphthalmia J:103785
Pax6Mhdaaey18/Pax6+
involves: C3HeB/FeJ 		cataract J:82809
microphthalmia J:82809
Pax6Mhdaaey18/Pax6Mhdaaey18
involves: C3HeB/FeJ 		abnormal embryonic/fetal subventricular zone morphology J:94457
abnormal forebrain development J:94457
abnormal neuron differentiation J:94457
abnormal telencephalon development J:94457
neonatal lethality, complete penetrance J:82809
thin cortical plate J:94457
Pax6Rgsc20/Pax6+
involves: C57BL/6JJcl * DBA/2JJcl 		developmental cataract J:133634
microphthalmia J:133634
Pax6Rgsc123/Pax6+
involves: C57BL/6JJcl * DBA/2JJcl 		developmental cataract J:133634
microphthalmia J:133634
Pax6Rgsc242/Pax6+
involves: C57BL/6JJcl * DBA/2JJcl 		developmental cataract J:133634
microphthalmia J:133634
Pax6Sey-2H/Pax6+
Not Specified 		decreased birth body size J:69257
embryonic lethality, incomplete penetrance J:69257
exencephaly J:69257
perinatal lethality, incomplete penetrance J:69257
postnatal lethality, incomplete penetrance J:69257
white spotting J:69257
Pax6Sey-2H/Pax6Sey-2H
Not Specified 		embryonic lethality before implantation, incomplete penetrance J:69257
Pax6Sey-3H/Pax6+
Not Specified 		decreased birth body size J:69257
perinatal lethality, incomplete penetrance J:69257
postnatal lethality, incomplete penetrance J:69257
white spotting J:69257
Pax6Sey-4H/Pax6+
involves: 101/H * C3H/HeCrj * C3H/HeH 		increased alimentary system tumor incidence J:124276
increased intestinal adenoma incidence J:124276
increased stomach tumor incidence J:124276
increased susceptibility to induced pancreatitis J:124276
increased tumor incidence J:124276
premature death J:124276
Pax6Sey-Dey/Pax6+
B6EiC3Sn a/A-Pax6Sey-Dey/J 		abnormal corneal epithelium morphology J:83791
abnormal corneal stroma morphology J:83791
decreased corneal epithelium thickness J:83791
Pax6Sey-Dey/Pax6+
C3H/HeJ-Pax6Sey-Dey 		abnormal lens development J:6072
abnormal retina pigment epithelium morphology J:6072
aniridia J:10820
belly spot J:6072
cataract J:6072
coloboma J:6072
decreased body size J:6072
decreased fetal size J:6072
exencephaly J:6072
fused cornea and lens J:6072
hypopigmentation J:6072
iris hypoplasia J:6072
microphthalmia J:6072
neonatal lethality, incomplete penetrance J:6072
normal neoplasm J:10820
normal renal/urinary system phenotype J:10820
retina fold J:6072
small lens J:6072
Pax6Sey-Dey/Pax6+
involves: C3H/HeJ 		coloboma J:14117
decreased body length J:14117
prenatal lethality, incomplete penetrance J:14117
Pax6Sey-Dey/Pax6Sey-Dey
C3H/HeJ-Pax6Sey-Dey 		embryonic lethality between implantation and somite formation, complete penetrance J:6072
Pax6Sey-Dey/Pax6Sey
involves: C3H/HeJ 		absent lens vesicle J:14117
absent nasal placodes J:14117
coloboma J:14117
Pax6Sey-Neu/Pax6+
C3.Cg-Pax6Sey-Neu 		abnormal eye development J:65597
abnormal lens development J:65597
Pax6Sey-Neu/Pax6+
involves: 102 * C3H 		abnormal Bowman membrane morphology J:83026
abnormal cornea anterior stroma morphology J:83026
abnormal cornea morphology J:83026
abnormal corneal epithelium morphology J:83791
abnormal corneal stroma morphology J:83026, J:83791
abnormal eye anterior chamber morphology J:83026
abnormal lens vesicle development J:83026
anterior iris synechia J:83026
corneal vascularization J:83026, J:114973
decreased corneal epithelium thickness J:83026, J:83791, J:114973
iris hypoplasia J:83026
microphthalmia J:83026
Pax6Sey-Neu/Pax6+
involves: 102 * C3H * C3H/HeN 		abnormal lens morphology J:119175
Pax6Sey-Neu/Pax6Sey-Neu
CBACa.Cg-Pax6Sey-Neu 		abnormal craniofacial bone morphology J:43913
abnormal nasal capsule morphology J:43913
Pax6Sey-Neu/Pax6Sey-Neu
involves: 102 * C3H 		abnormal brain commissure morphology J:41401
abnormal forebrain morphology J:41401
abnormal olfactory epithelium morphology J:65749
abnormal olfactory nerve morphology J:65749
abnormal optic vesicle formation J:41401
abnormal submandibular gland morphology J:74539
decreased circulating growth hormone level J:56185
neonatal lethality, complete penetrance J:56185
submandibular gland hypoplasia J:74539
Pax6Sey-Neu/Pax6Sey-Neu
involves: 102 * C3H * CD-1 		abnormal hormone level J:41624
abnormal pallium development J:66590
absent pancreatic alpha cells J:41624
absent pancreatic beta cells J:41624
Pax6Sey-Neu/Pax6Sey-Neu
involves: 102 * C3H * ICR 		abnormal cerebellar granule cell morphology J:103551
abnormal cerebellum external granule cell layer morphology J:103551
abnormal cerebellum morphology J:103551
abnormal cerebellum vermis morphology J:103551
abnormal lens induction J:51570
ectopic Purkinje cell J:103551
Pax6Sey-Neu/Pax6Sey-Neu
involves: 102/El * C3H/Rl 		abnormal endocrine pancreas development J:132598
Pax6Sey-Neu/Pax6tm1.1Zkoz
involves: 102/El * C3H/Rl 		abnormal optic cup morphology J:208421
Pax6Sey/Pax6+
B10.Cg-Pax6Sey 		retina fold J:8534
small lens J:8534
Pax6Sey/Pax6+
C.Cg-Pax6Sey 		abnormal lens vesicle development J:119940
Pax6Sey/Pax6+
involves: C57BL/6 		abnormal optic cup morphology J:2301
microphthalmia J:2301
Pax6Sey/Pax6+
Not Specified 		abnormal anterior eye segment morphology J:71087
abnormal corneal epithelium morphology J:5093
abnormal eye anterior chamber morphology J:71087
abnormal lens development J:71087
abnormal lens epithelium morphology J:5093
abnormal lens fiber morphology J:71087
abnormal lens morphology J:71087
abnormal lens vesicle development J:71087
abnormal optic nerve morphology J:22316
abnormal retina morphology J:5093
abnormal retina photoreceptor layer morphology J:5093
abnormal retina pigment epithelium morphology J:5093
decreased body size J:12101
delayed eyelid fusion J:71087
microphthalmia J:12101, J:71087
Pax6Sey/Pax6Sey
B10.Cg-Pax6Sey 		abnormal nasal bone morphology J:8534
absent nasal pit J:8534
absent olfactory bulb J:8534
aphakia J:8534
decreased eye pigmentation J:8534
perinatal lethality, incomplete penetrance J:8534
Pax6Sey/Pax6Sey
C.Cg-Pax6Sey 		abnormal cornea morphology J:119940
abnormal corneal endothelium morphology J:119940
abnormal iridocorneal angle J:119940
anterior iris synechia J:119940
corneal vascularization J:119940
Pax6Sey/Pax6Sey
CBACa.Cg-Pax6Sey 		abnormal craniofacial bone morphology J:43913
abnormal nasal capsule morphology J:43913
normal craniofacial phenotype J:43913
Pax6Sey/Pax6Sey
involves: C57BL/6 		abnormal nasal cavity morphology J:2301
anophthalmia J:2301
neonatal lethality, complete penetrance J:2301
short snout J:2301
Pax6Sey/Pax6Sey
involves: C57BL/6J * DBA/2J 		abnormal brain development J:126065
abnormal embryonic/fetal subventricular zone morphology J:94457
abnormal forebrain development J:94457
abnormal neuron differentiation J:94457
abnormal telencephalon development J:94457
thin cortical plate J:94457
Pax6Sey/Pax6Sey
involves: ICR 		abnormal cerebellar granule cell morphology J:103551
abnormal cerebellum external granule cell layer morphology J:103551
abnormal cerebellum morphology J:103551
abnormal cerebellum vermis morphology J:103551
ectopic Purkinje cell J:103551
Pax6Sey/Pax6Sey
involves: Swiss 		abnormal cerebral cortex morphology J:119877
abnormal lens vesicle development J:25250
abnormal optic vesicle formation J:25250
abnormal respiratory system development J:25250
absent lens vesicle J:25250
absent nasal placodes J:25250
thin cerebral cortex J:119877
Pax6Sey/Pax6Sey
Not Specified 		abnormal diencephalon morphology J:98539
abnormal neuron differentiation J:112802
abnormal nose morphology J:22316
abnormal pretectal region morphology J:98539
abnormal synaptic transmission J:87771
abnormal ventral interneuron 1 morphology J:87771
anophthalmia J:22316
perinatal lethality, complete penetrance J:22316
respiratory failure J:22316
small thalamus J:98539
Pax6tm1.1Ued/Pax6tm1.1Ued
involves: 129P2/OlaHsd * FVB/N * ICR 		abnormal eye morphology J:151427
abnormal facial morphology J:151427
abnormal telencephalon morphology J:151427
Pax6tm1.1Xzh/Pax6tm1.1Xzh
B6.129S6-Pax6tm1.1Xzh 		abnormal lacrimal gland morphology J:182769
normal vision/eye phenotype J:182769
Pax6tm1.1Zkoz/Pax6Sey-Neu
Tg(Rax-cre)1Zkoz/0
involves: 102/El * C3H/Rl 		abnormal optic cup morphology J:208421
abnormal optic placode morphology J:208421
absent lens vesicle J:208421
aphakia J:208421
Pax6tm1.1Zkoz/Pax6tm1.1Zkoz
Tg(Pax6-cre,GFP)2Pgr/0
Not Specified 		abnormal retina development J:208421
Pax6tm1.1Zkoz/Pax6tm1.1Zkoz
Tg(Rax-cre)1Zkoz/0
Not Specified 		abnormal cell cycle J:208421
abnormal cell cycle checkpoint function J:208421
abnormal eye physiology J:208421
abnormal lens morphology J:208421
abnormal mitosis J:208421
abnormal optic cup morphology J:208421
abnormal retina development J:208421
abnormal retina layer morphology J:208421
abnormal retina progenitor cell morphology J:208421
absent amacrine cells J:208421
decreased cell proliferation J:208421
decreased total retina thickness J:208421
increased retina apoptosis J:208421
microphthalmia J:208421
retina hypoplasia J:208421
normal vision/eye phenotype J:208421
Pax6tm1.2Xzh/Pax6tm1.2Xzh
B6.129S6-Pax6tm1.2Xzh 		abnormal lens fiber morphology J:182769
abnormal lens morphology J:182769
coloboma J:182769
corneal-lenticular stalk J:182769
microphthalmia J:182769
Pax6tm1Gfs/Pax6+
involves: 129S7/SvEvBrd 		abnormal iris morphology J:76576
iris hypoplasia J:76576
mydriasis J:76576
Pax6tm1Gfs/Pax6tm1Gfs
involves: 129S7/SvEvBrd 		abnormal corneal stroma morphology J:76576
abnormal iris morphology J:76576
abnormal lens epithelium morphology J:76576
abnormal lens morphology J:76576
abnormal pupil morphology J:76576
abnormal retina morphology J:76576
aniridia J:76576
iris hypoplasia J:76576
mydriasis J:76576
Pax6tm1Gfs/Pax6tm1Gfs
involves: 129S7/SvEvBrd * C57BL/6 		normal nervous system phenotype J:94457
Pax6tm1Lan/Pax6+
involves: 129S1/Sv * 129X1/SvJ 		abnormal lens vesicle development J:73524
abnormal optic placode morphology J:73524
Pax6tm1Lan/Pax6tm1Lan
involves: 129S1/Sv * 129X1/SvJ 		abnormal lens epithelium morphology J:73524
abnormal lens fiber morphology J:73524
abnormal lens morphology J:73524
abnormal lens vesicle development J:73524
abnormal optic placode morphology J:73524
Pax6tm1Pgr/Pax6+
involves: 129S1/Sv * 129X1/SvJ 		abnormal iridocorneal angle J:163191
absent eye anterior chamber J:163191
anterior iris synechia J:163191
fused cornea and lens J:163191
Pax6tm1Pgr/Pax6tm1Pgr
involves: 129S1/Sv * 129X1/SvJ 		abnormal CNS synaptic transmission J:106437
abnormal neuron physiology J:106437
abnormal ventral interneuron 0 morphology J:106437
abnormal ventral interneuron 1 morphology J:106437
abnormal ventral interneuron 3 morphology J:106437
abnormal ventral interneuron morphology J:106437
Pax6tm1Pgr/Pax6tm1Pgr
involves: 129S1/Sv * 129X1/SvJ * NMRI 		absent olfactory bulb J:40439
absent pancreatic alpha cells J:40439
anophthalmia J:40439
disorganized pancreatic islets J:40439
neonatal lethality, complete penetrance J:40439
Pax6tm1Pgr/Pax6tm2Pgr
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129S1/Sv * 129X1/SvJ * FVB * NMRI 		abnormal optic cup morphology J:65765
abnormal optic vesicle formation J:65765
absent optic placodes J:65765
decreased circulating insulin level J:90642
decreased pancreatic alpha cell number J:90642
decreased pancreatic beta cell number J:90642
hyperglycemia J:90642
increased circulating ketone body level J:90642
postnatal growth retardation J:90642
postnatal lethality, complete penetrance J:90642
Pax6tm1Ued/Pax6tm1Ued
involves: 129P2/OlaHsd * ICR 		no abnormal phenotype detected J:151427
Pax6tm1Ued/Pax6tm1Ued
Tg(Six3-cre)69Frty/0
involves: 129P2/OlaHsd * ICR 		abnormal brain internal capsule morphology J:151427
abnormal telencephalon development J:151427
Pax6tm2Pgr/Pax6+
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129S1/Sv * 129X1/SvJ * FVB 		abnormal corneal stroma morphology J:163191
abnormal iridocorneal angle J:163191
abnormal optic nerve morphology J:163191
absent Schlemm's canal J:163191
absent trabecular meshwork J:163191
anterior iris synechia J:163191
fused cornea and lens J:163191
microphthalmia J:163191
ocular hypertension J:163191
optic nerve degeneration J:163191
optic nerve hypoplasia J:163191
small lens J:163191
Pax6tm2Pgr/Pax6+
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal iris stroma morphology J:163191
normal vision/eye phenotype J:163191
Pax6tm2Pgr/Pax6+
Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/0
Tg(Dct-cre)1Apdn/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal iris morphology J:152253
iris hypoplasia J:152253
Pax6tm2Pgr/Pax6+
Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0
Tg(Dct-cre)1Apdn/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal ciliary body morphology J:152253
abnormal iris morphology J:152253
iris hypoplasia J:152253
Pax6tm2Pgr/Pax6+
Tg(Dct-cre)1Apdn/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal intraocular muscle morphology J:152253
impaired pupillary reflex J:152253
iris hypoplasia J:152253
irregularly shaped pupil J:152253
mydriasis J:152253
Pax6tm2Pgr/Pax6tm2Pgr
Tg(Cryaa-cre)10Mlr/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		abnormal lens development J:152850
abnormal lens epithelium morphology J:152850
abnormal lens fiber morphology J:152850
abnormal lens morphology J:152850
cataract J:152850
increased cornea thickness J:152850
increased lens epithelium apoptosis J:152850
microphthalmia J:152850
small lens J:152850
Pax6tm2Pgr/Pax6tm2Pgr
Tg(Dct-cre)1Apdn/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal anterior eye segment morphology J:152253
abnormal iris morphology J:152253
abnormal lens morphology J:152253
abnormal retina pigment epithelium morphology J:152253
abnormal vitreous body morphology J:152253
absent ciliary body J:152253
cataract J:152253
increased opacity of vitreous body J:152253
iris hypoplasia J:152253
microphthalmia J:152253
retina hypoplasia J:152253
small lens J:152253
Pax6tm2Pgr/Pax6tm2Pgr
Tg(Pax6-cre,GFP)1Pgr/0
involves: FVB * NMRI 		decreased circulating insulin level J:90642
decreased pancreatic alpha cell number J:90642
decreased pancreatic beta cell number J:90642
hyperglycemia J:90642
increased circulating ketone body level J:90642
postnatal growth retardation J:90642
postnatal lethality, complete penetrance J:90642
Pax6tm2Pgr/Pax6tm2Pgr
Tg(Pdx1-cre)6Cvw/0
involves: FVB * NMRI 		decreased pancreatic alpha cell number J:90642
decreased pancreatic beta cell number J:90642
postnatal lethality, complete penetrance J:90642
Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/0
Tg(Dct-cre)1Apdn/0
Not Specified 		normal vision/eye phenotype J:152253
Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0
Tg(Dct-cre)1Apdn/0
Not Specified 		abnormal ciliary body morphology J:152253
abnormal iris morphology J:152253
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory