132 phenotypes from 9 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pax21Neu/Pax2+ involves: 102	increased kidney apoptosis	J:136502
	increased pancreatic beta cell mass	J:89465
	increased pancreatic islet number	J:89465
	pancreatic islet hyperplasia	J:89465
Pax21Neu/Pax2+ involves: 102 * C3H	abnormal optic disk morphology	J:37055
	abnormal retina layer morphology	J:37055
	abnormal retina nerve fiber layer morphology	J:37055
	abnormal retina neuronal layer morphology	J:37055
	abnormal retina vasculature morphology	J:37055
	decreased retina ganglion cell number	J:37055
	kidney cyst	J:37055
	single kidney	J:37055
	small kidney	J:37055
	thin retina ganglion layer	J:37055
Pax21Neu/Pax2+ involves: 102 * C57BL/6	abnormal kidney development	J:86661
	abnormal nephrogenic zone morphology	J:59408
	absent kidney	J:86661
	decreased nephron number	J:59408, J:86661
	decreased renal glomerulus number	J:59408, J:86661
	impaired branching involved in ureteric bud morphogenesis	J:59408
	increased kidney apoptosis	J:59408, J:86661
	kidney cyst	J:59408
	kidney medulla hypoplasia	J:59408
	lethality throughout fetal growth and development, incomplete penetrance	J:86661
	postnatal lethality, incomplete penetrance	J:86661
	renal hypoplasia	J:59408
	single kidney	J:59408
	small kidney	J:59408, J:86661
Pax21Neu/Pax2+ involves: 102 * CD-1	abnormal ureter morphology	J:145105
	bifid ureter	J:145105
	dilated ureter	J:145105
	double ureter	J:145105
	ectopic ureteric bud	J:145105
	hydroureter	J:145105
	small kidney	J:145105
	vesicoureteral reflux	J:145105
Pax21Neu/Pax2+ Tg(Hoxb7-EGFP)33Cos/? involves: 102 * C57BL/6 * CBA * CD-1	abnormal ureter development	J:145105
	abnormal ureteric bud morphology	J:145105
	duplex kidney	J:145105
	ectopic ureteric bud	J:145105
	impaired branching involved in ureteric bud morphogenesis	J:145105
Pax21Neu/Pax21Neu involves: 102	normal endocrine/exocrine gland phenotype	J:77446
	increased pancreatic beta cell mass	J:89465
	increased pancreatic islet number	J:89465
	neonatal lethality, complete penetrance	J:89465
	pancreatic islet hyperplasia	J:89465
Pax21Neu/Pax21Neu involves: 102 * C3H	abnormal brain development	J:37055
	abnormal choroid plexus morphology	J:37055
	abnormal corpora quadrigemina morphology	J:37055
	abnormal ear development	J:37055
	abnormal inner ear morphology	J:37055
	abnormal kidney development	J:37055
	abnormal metanephric mesenchyme morphology	J:37055
	abnormal midbrain morphology	J:37055
	abnormal optic nerve morphology	J:37055
	abnormal optic stalk morphology	J:37055
	abnormal vestibulocochlear ganglion morphology	J:37055
	absent cerebellum	J:37055
	absent midbrain-hindbrain boundary	J:37055
	absent semicircular canal ampulla	J:37055
	absent utricle	J:37055
	delayed neural tube closure	J:37055
	dilated endolymphatic duct	J:37055
	exencephaly	J:37055
Pax2M1Bpb/Pax2+ C57BL/6-Pax2M1Bpb	abnormal eye development	J:159240
	abnormal midbrain-hindbrain boundary morphology	J:159240
	abnormal optic disk morphology	J:159240
	abnormal optic nerve morphology	J:159240
	abnormal renal tubule morphology	J:159240
	abnormal retina blood vessel morphology	J:159240
	abnormal retina blood vessel pattern	J:159240
	abnormal retina morphology	J:159240
	abnormal retina pigment epithelium morphology	J:159240
	hydronephrosis	J:159240
	hydroureter	J:159240
	kidney cyst	J:159240
	renal hypoplasia	J:159240
Pax2M1Bpb/Pax2+ involves: C3H/HeJ * C57BL/6	abnormal optic nerve morphology	J:159240
Pax2M1Bpb/Pax2M1Bpb C57BL/6-Pax2M1Bpb	abnormal kidney development	J:159240
	abnormal midbrain-hindbrain boundary morphology	J:159240
	abnormal neural crest morphology	J:159240
	delayed optic fissure closure	J:159240
	lethality throughout fetal growth and development, incomplete penetrance	J:159240
	normal nervous system phenotype	J:159240
	perinatal lethality, complete penetrance	J:159240
	renal hypoplasia	J:159240
	uveal coloboma	J:159240
Pax2Opdc/Pax2+ involves: BALB/cAnN * C3H/HeN	abnormal eye morphology	J:75964
	abnormal optic nerve morphology	J:75964
	optic disk coloboma	J:75964
Pax2tm1.1Gdr/Pax2tm1.1Gdr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal kidney development	J:184878
	absent kidney	J:184878
	exencephaly	J:184878
	neonatal lethality, complete penetrance	J:184878
Pax2tm1Cjt/Pax2tm1Cjt involves: 129S1/Sv * C57BL/6J	abnormal inner ear morphology	J:74492
	absent cochlea	J:74492
	absent cochlear ganglion	J:74492
	absent kidney	J:74492
	absent ureter	J:74492
Pax2tm1Gdr/Pax2tm1.1Gdr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal kidney development	J:184878
	neonatal lethality, complete penetrance	J:184878
Pax2tm1Gdr/Pax2tm1Gdr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal kidney lobule morphology	J:184878
	decreased nephron number	J:184878
	double ureter	J:184878
	kidney medulla cyst	J:184878
	renal hypoplasia	J:184878
Pax2tm1Mbu/Pax2tm1Mbu C3.129P2-Pax2tm1Mbu	abnormal brain commissure morphology	J:63683
	abnormal brain development	J:63683
	abnormal inner ear morphology	J:63683
	abnormal midbrain morphology	J:63683
	abnormal optic fissure closure	J:63683
	abnormal otolith organ morphology	J:63683
	abnormal retina morphology	J:63683
	abnormal retina pigmentation	J:63683
	absent cerebellum	J:63683
	absent cochlea	J:63683
	absent cochlear ganglion	J:63683
	absent epididymis	J:63683
	absent kidney	J:63683
	absent midbrain-hindbrain boundary	J:63683
	absent oviduct	J:63683
	absent seminal vesicle	J:63683
	absent tectum	J:63683
	absent ureter	J:63683
	absent uterus	J:63683
	absent vagina	J:63683
	absent vas deferens	J:63683
	absent vestibular saccule	J:63683
	Mullerian duct degeneration	J:63683
	perinatal lethality, complete penetrance	J:63683
	Wolffian duct degeneration	J:63683
Pax2tm1Mbu/Pax2tm2(Pax5)Mbu C3.129P2-Pax2tm1Mbu Pax2tm2(Pax5)Mbu	abnormal cochlea morphology	J:63683
	abnormal kidney development	J:63683
	abnormal otolith organ morphology	J:63683
	abnormal retina morphology	J:63683
	abnormal retina pigmentation	J:63683
	absent kidney	J:63683
	absent ureter	J:63683
	normal reproductive system phenotype	J:63683
	small kidney	J:63683
	normal vision/eye phenotype	J:63683
Pax2tm1Pgr/Pax2+ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal inner ear morphology	J:119574
	decreased cochlea coiling	J:119574
Pax2tm1Pgr/Pax2+ involves: 129S1/Sv * 129X1/SvJ	abnormal kidney calyx morphology	J:30343
	decreased nephron number	J:30343
	exencephaly	J:36834
	normal hearing/vestibular/ear phenotype	J:36834
	kidney cortex hypoplasia	J:30343
	optic nerve coloboma	J:36834
	renal hypoplasia	J:30343
	small kidney	J:30343
Pax2tm1Pgr/Pax2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal inner ear morphology	J:119574
	decreased cochlea coiling	J:119574
Pax2tm1Pgr/Pax2+ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ	decreased renal glomerulus number	J:117753
	renal hypoplasia	J:117753
Pax2tm1Pgr/Pax2tm1Pgr involves: 129S1/Sv * 129X1/SvJ	abnormal axon extension	J:36834
	abnormal brain morphology	J:36834
	abnormal diencephalon morphology	J:36834
	abnormal eye development	J:36834
	abnormal intermediate mesoderm morphology	J:30343
	abnormal kidney development	J:30343
	abnormal mesonephric mesenchyme morphology	J:30343
	abnormal mesonephros morphology	J:30343
	abnormal metanephric mesenchyme morphology	J:30343
	abnormal neural tube closure	J:36834
	abnormal optic fissure closure	J:36834
	abnormal optic nerve innervation	J:36834
	abnormal optic nerve morphology	J:36834
	abnormal optic stalk morphology	J:36834
	abnormal optic tract morphology	J:36834
	abnormal retina pigmentation	J:36834
	abnormal testis morphology	J:30343
	absent cochlea	J:36834, J:92326
	absent cochlear ganglion	J:36834
	absent cochlear nerve	J:36834
	absent efferent ductules of testis	J:30343
	absent epididymis	J:30343
	absent kidney	J:30343
	absent metanephros	J:30343
	absent optic chiasm	J:36834
	absent organ of Corti	J:36834
	absent oviduct	J:30343
	absent seminal vesicle	J:30343
	absent ureter	J:30343
	absent ureteric bud	J:30343
	absent uterine horn	J:30343
	absent vagina	J:30343
	absent vas deferens	J:30343
	coloboma	J:36834
	exencephaly	J:36834
	incomplete rostral neuropore closure	J:36834
	Mullerian duct degeneration	J:30343
	rudimentary Mullerian ducts	J:30343
	rudimentary Wolffian ducts	J:30343
	short scala media	J:36834
	Wolffian duct degeneration	J:30343
Pax2tm1Pgr/Pax2tm1Pgr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cochlea morphology	J:92326
	abnormal cochlear sensory epithelium morphology	J:92326
	abnormal common crus morphology	J:92326
	abnormal endolymphatic duct morphology	J:92326
	abnormal inner ear morphology	J:92326
	abnormal organ of Corti morphology	J:92326
	abnormal scala media morphology	J:92326
	abnormal semicircular canal ampulla morphology	J:92326
	abnormal semicircular canal morphology	J:92326
	abnormal stria vascularis morphology	J:92326
	abnormal vestibular saccular macula morphology	J:92326
	absent cochlear ganglion	J:92326
	absent vestibular saccule	J:92326
	decreased cochlea coiling	J:92326
	exencephaly	J:92326
	short endolymphatic duct	J:92326
	small endolymphatic duct	J:92326
	small vestibular ganglion	J:92326
Pax2tm1Pgr/Pax2tm1Pgr involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal endolymphatic duct morphology	J:119574
	abnormal inner ear vestibule morphology	J:119574
	abnormal utricle morphology	J:119574
	abnormal vestibular saccule morphology	J:119574