Ctnnb1tm2.1Kem/Ctnnb1+
Otx2tm1(Dkk1)Imat/Otx2tm1(Dkk1)Imat
involves: 129/Sv * C57BL/6 * CBA
|
abnormal rostral-caudal axis patterning |
J:103272
|
Emx1tm1Sia/Emx1tm1Sia
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
|
normal
nervous system phenotype |
J:98539
|
Emx2tm1Sia/Emx2+
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
|
abnormal forebrain morphology |
J:70745
|
Emx2tm1Sia/Emx2tm1Sia
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
|
abnormal adenohypophysis morphology |
J:70745
|
|
abnormal Ammon gyrus morphology |
J:70745
|
|
abnormal anterior commissure morphology |
J:70745
|
|
abnormal cerebral cortex morphology |
J:70745,
J:98539
|
|
abnormal corpus callosum morphology |
J:70745
|
|
abnormal forebrain development |
J:163926
|
|
abnormal forebrain morphology |
J:70745
|
|
abnormal hippocampal fornix morphology |
J:70745
|
|
abnormal hippocampus region morphology |
J:70745
|
|
abnormal lateral ganglionic eminence morphology |
J:70745
|
|
abnormal lens morphology |
J:70745
|
|
abnormal medial ganglionic eminence morphology |
J:70745
|
|
abnormal midbrain morphology |
J:70745
|
|
abnormal midbrain-hindbrain boundary morphology |
J:70745
|
|
abnormal olfactory bulb mitral cell layer morphology |
J:70745
|
|
abnormal olfactory sensory neuron morphology |
J:70745
|
|
abnormal posterior commissure morphology |
J:70745
|
|
abnormal pretectal region morphology |
J:70745
|
|
abnormal telencephalon morphology |
J:70745,
J:98539
|
|
abnormal thalamus morphology |
J:70745
|
|
absent choroid plexus |
J:70745,
J:98539
|
|
absent dentate gyrus |
J:70745
|
|
absent hippocampal fimbria |
J:70745
|
|
absent hippocampus |
J:70745,
J:98539
|
|
enlarged tectum |
J:70745
|
|
lethality throughout fetal growth and development, complete penetrance |
J:70745
|
|
retina hyperplasia |
J:70745
|
|
small olfactory bulb |
J:70745
|
Emx2tm1Sia/Emx2tm1Sia
Otx2tm7Sia/Otx2tm7Sia
involves: C57BL/6NCrlj * CBA/JNCrlj
|
absent diencephalon |
J:91012
|
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt
Otx2tm1(OTX1)Asim/Otx2tm1(OTX1)Asim
involves: 129 * C57BL/6 * DBA/2
|
abnormal embryonic neuroepithelium morphology |
J:72725
|
|
abnormal heart morphology |
J:72725
|
|
abnormal neural plate morphology |
J:72725
|
|
abnormal neural tube morphology |
J:72725
|
|
absent embryonic telencephalon |
J:72725
|
|
absent midbrain-hindbrain boundary |
J:72725
|
|
absent nasal placodes |
J:72725
|
|
absent optic placodes |
J:72725
|
|
absent optic vesicle |
J:72725
|
|
absent pharyngeal arches |
J:72725
|
|
decreased embryo size |
J:72725
|
|
dilated heart |
J:72725
|
|
embryonic lethality during organogenesis, complete penetrance |
J:72725
|
|
exencephaly |
J:72725
|
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt
Otx2tm1Pas/Otx2tm2Asim
involves: 129 * C57BL/6 * DBA/2
|
abnormal brain development |
J:72725
|
|
abnormal head development |
J:72725
|
|
normal
cardiovascular system phenotype |
J:72725
|
|
normal
mortality/aging |
J:72725
|
Gdf7tm3(cre)Tmj/Gdf7+
Otx2tm6Asim/Otx2tm6Asim
Tg(CAG-cat,-EGFP)1Rbns/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal cerebral cortex morphology |
J:194049
|
|
abnormal choroid plexus morphology |
J:194049
|
|
abnormal nervous system physiology |
J:194049
|
Gt(ROSA)26Sortm1.1(Otx2)Daac/Gt(ROSA)26Sortm1.1(Otx2)Daac
Slc6a3tm1.1(cre)Bkmn/Slc6a3+
Tg(CAG-Otx2,-GFP)21Asim/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
decreased dopaminergic neuron number |
J:166896
|
|
decreased susceptibility to dopaminergic neuron neurotoxicity |
J:166896
|
Otx1tm1Asim/Otx1tm1Asim
Otx2tm1Pas/Otx2+
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal dopaminergic neuron morphology |
J:88192
|
|
abnormal neuron morphology |
J:88192
|
|
abnormal serotonergic neuron morphology |
J:88192
|
Otx1tm1Asim/Otx1tm2(otd)Asim
Otx2tm1Pas/Otx2+
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal brain morphology |
J:47899
|
|
abnormal cerebellum morphology |
J:47899
|
|
abnormal midbrain morphology |
J:47899
|
|
perinatal lethality, complete penetrance |
J:47899
|
Otx1tm1Sia/Otx1+
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
|
abnormal brain development |
J:51989
|
|
abnormal cartilage morphology |
J:73592
|
|
abnormal cerebral cortex morphology |
J:73592
|
|
abnormal cerebral hemisphere morphology |
J:51989
|
|
abnormal cranium morphology |
J:73592
|
|
abnormal diencephalon morphology |
J:73592
|
|
abnormal forebrain morphology |
J:51989
|
|
abnormal hypothalamus morphology |
J:73592
|
|
abnormal inferior colliculus morphology |
J:73592
|
|
abnormal mammillary body morphology |
J:73592
|
|
abnormal metencephalon morphology |
J:51989
|
|
abnormal midbrain morphology |
J:51989,
J:73592
|
|
abnormal midbrain-hindbrain boundary morphology |
J:51989
|
|
abnormal nervous system morphology |
J:73592
|
|
abnormal oculomotor nerve morphology |
J:73592
|
|
abnormal oculomotor nucleus morphology |
J:73592
|
|
abnormal optic nerve morphology |
J:73592
|
|
abnormal orbitosphenoid bone morphology |
J:73592
|
|
abnormal posterior commissure morphology |
J:73592
|
|
abnormal pretectal region morphology |
J:51989
|
|
abnormal red nucleus morphology |
J:73592
|
|
abnormal rhombic lip morphology |
J:73592
|
|
abnormal sphenoid bone morphology |
J:73592
|
|
abnormal superior colliculus morphology |
J:73592
|
|
abnormal tegmentum morphology |
J:73592
|
|
abnormal telencephalon morphology |
J:51989,
J:73592
|
|
abnormal trigeminal V mesencephalic nucleus morphology |
J:73592
|
|
abnormal trochlear nerve morphology |
J:73592
|
|
basisphenoid bone foramen |
J:73592
|
|
decreased midbrain size |
J:73592
|
|
decreased substantia nigra size |
J:73592
|
|
enlarged cerebellum |
J:51989,
J:73592
|
|
enlarged cerebral aqueduct |
J:73592
|
|
increased pons size |
J:51989
|
|
prenatal lethality, complete penetrance |
J:73592
|
|
presphenoid bone hypoplasia |
J:73592
|
|
small hippocampus |
J:51989,
J:73592
|
|
small olfactory bulb |
J:73592
|
|
small thalamus |
J:51989,
J:73592
|
Otx1tm1Sia/Otx1+
Otx2tm2(Otx1)Sia/Otx2+
involves: C57BL/6 * CBA
|
abnormal midbrain-hindbrain boundary morphology |
J:51989
|
|
decreased midbrain size |
J:51989
|
|
increased rhombomere 1 size |
J:51989
|
Otx1tm1Sia/Otx1tm1Sia
Otx2tm5Sia/Otx2tm5Sia
involves: C57BL/6NCrlj * CBA/JNCrlj
|
abnormal brain development |
J:91011
|
|
absent diencephalon |
J:91011
|
|
absent midbrain |
J:91011
|
Otx1tm1Sia/Otx1tm1Sia
Otx2tm8.2Sia/Otx2tm8.2Sia
involves: C57BL/6 * CBA
|
abnormal cerebral cortex morphology |
J:166617
|
|
abnormal embryonic/fetal subventricular zone morphology |
J:166617
|
|
abnormal midbrain-hindbrain boundary morphology |
J:166617
|
|
absent diencephalon |
J:166617
|
|
absent midbrain |
J:166617
|
|
absent tectum |
J:166617
|
|
absent tegmentum |
J:166617
|
|
increased pons size |
J:166617
|
Otx1tm1Sia/Otx1tm1Sia
Otx2tm10Sia/Otx2tm10Sia
involves: C57BL/6NCrlj * CBA/JNCrlj
|
abnormal embryonic neuroepithelium morphology |
J:207608
|
Otx1tm2(otd)Asim/Otx1tm2(otd)Asim
Otx2tm1Pas/Otx2+
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal midbrain morphology |
J:47899
|
Otx2tm1(Dkk1)Imat/Otx2tm1(Dkk1)Imat
involves: C57BL/6 * CBA
|
abnormal rostral-caudal axis patterning |
J:103272
|
Otx2tm1(OTX1)Asim/Otx2tm1(OTX1)Asim
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal anterior head development |
J:49817
|
|
abnormal cephalic neural fold morphology |
J:49817
|
|
abnormal craniofacial development |
J:49817
|
|
abnormal embryonic neuroepithelium morphology |
J:49817
|
|
abnormal first pharyngeal arch morphology |
J:49817
|
|
abnormal forebrain development |
J:49817
|
|
abnormal maxillary prominence morphology |
J:49817
|
|
abnormal midbrain development |
J:49817
|
|
acephaly |
J:49817
|
|
rostral body truncation |
J:49817
|
Otx2tm1.1(cre/ERT2)Mgoe/Otx2tm6Asim
Tg(CAG-cat,-EGFP)1Rbns/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
|
abnormal choroid plexus morphology |
J:194049
|
|
absent choroid plexus |
J:194049
|
Otx2tm2(Otx1)Sia/Otx2+
involves: C57BL/6 * CBA
|
abnormal eye morphology |
J:51989
|
|
abnormal mandible morphology |
J:51989
|
|
normal
craniofacial phenotype |
J:51989
|
Otx2tm2(Otx1)Sia/Otx2tm2(Otx1)Sia
involves: C57BL/6 * CBA
|
abnormal brain development |
J:51989
|
|
abnormal forebrain development |
J:51989
|
|
abnormal midbrain development |
J:51989
|
|
absent maxilla |
J:51989
|
|
absent olfactory bulb |
J:51989
|
|
absent pituitary gland |
J:51989
|
|
anophthalmia |
J:51989
|
|
normal
embryo phenotype |
J:51989
|
|
neonatal lethality, complete penetrance |
J:51989
|
|
otocephaly |
J:51989
|
|
small mandible |
J:51989
|
Otx2tm3(Emx2)Sia/Otx2+
involves: C57BL/6 * CBA
|
abnormal pretectal region morphology |
J:70745
|
Otx2tm3(otd)Asim/Otx2tm3(otd)Asim
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal forebrain development |
J:72726
|
|
abnormal head morphology |
J:72726
|
|
abnormal midbrain-hindbrain boundary development |
J:72726
|
|
acephaly |
J:72726
|
|
exencephaly |
J:72726
|
Otx2tm4(otd)Asim/Otx2tm4(otd)Asim
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal first pharyngeal arch morphology |
J:72726
|
|
abnormal maxillary prominence morphology |
J:72726
|
|
acephaly |
J:72726
|
|
decreased body size |
J:72726
|
Otx2tm5(OTX2)Asim/Otx2tm5(OTX2)Asim
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal forebrain development |
J:72726
|
|
abnormal head morphology |
J:72726
|
|
abnormal midbrain development |
J:72726
|
|
acephaly |
J:72726
|
Otx2tm7(OTX1)Asim/Otx2tm7(OTX1)Asim
involves: 129P2/OlaHsd * C57BL/6 * (C57BL/6 x DBA/2)F1 * DBA/2
|
normal
nervous system phenotype |
J:89361
|
|
no abnormal phenotype detected |
J:89361
|
Rr103tm3.1Sia/Rr103tm3.1Sia
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
|
absent diencephalon |
J:163926
|
Rr103tm3Sia/Rr103tm3Sia
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
|
absent diencephalon |
J:163926
|
Excel File
Analysis Tools