Ntrk2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
MGI:97384

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bdnf^tm1Jae/Bdnf^tm2(Ntf5)Jae Ntrk2^tm1Kln/Ntrk2^tm1Kln involves: 129S4/SvJae	decreased sensory neuron number	J:61340
	head bobbing	J:61340
	hyperactivity	J:61340
	spinning	J:61340
Bdnf^tm1Par/Bdnf⁺ Ntrk2^tm1.1Tes/Ntrk2⁺ B6.129S1-Bdnf^tm1Par Ntrk2^tm1.1Tes	increased aggression towards male mice	J:144845
Bdnf^tm1Par/Bdnf⁺ Ntrk2^tm1.1Tes/Ntrk2^tm1.1Tes B6.129S1-Bdnf^tm1Par Ntrk2^tm1.1Tes	increased aggression towards male mice	J:144845
	increased body weight	J:144845
Bdnf^tm2(Ntf5)Jae/Bdnf^tm2(Ntf5)Jae Ntrk2^tm1Kln/Ntrk2^tm1Kln involves: 129S4/SvJae	hyperactivity	J:61340
Mirc35^tm1.1Pern/Mirc35^tm1.1Pern Ntrk2^{tm1.1(cre/ERT2)Pern}/Ntrk2⁺ involves: 129S2/SvPas * C57BL/6J * CBA/J	abnormal mechanoreceptor morphology	J:270955
Ntrk2^tm1.1Tes/Ntrk2⁺ Rb(12.Ts17¹⁶65Dn)2Cje/0 involves: 129S1/Sv * C3H/HeSnJ * C57BL/6JEi	normal nervous system phenotype	J:110478
Ntrk2^tm1Kln/Ntrk2^tm1Kln Ntrk3^tm1Kln/Ntrk3^tm1Kln involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cochlear nerve morphology	J:75365
	decreased sensory neuron number	J:75365
Ntrk2^tm2Kln/Ntrk2^tm2Kln Slc1a3^{tm1(cre/ERT2)Mgoe}/? Gt(ROSA)26Sor^tm1Sor/? involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * SJL	abnormal dendrite morphology	J:143452
	abnormal neuron differentiation	J:143452
	decreased locomotor activity	J:143452
	increased thigmotaxis	J:143452
	reduced long-term potentiation	J:143452
Ntrk2^tm2Kln/Ntrk2^tm2Kln Slc1a3^{tm1(cre/ERT2)Mgoe}/? Tg(CAG-Bgeo/GFP)21Lbe/? involves: 129/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:143452

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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