80 phenotypes from 5 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kiss1tm1.1(cre)Uboe/Kiss1+ Nhlh2tm2Thbr/Nhlh2tm2Thbr involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * C57BL/6J	normal adipose tissue phenotype	J:199640
	normal growth/size/body region phenotype	J:199640
	normal reproductive system phenotype	J:199640
Nhlh2em1(IMPC)Mbp/Nhlh2em1(IMPC)Mbp C57BL/6N-Nhlh2em1(IMPC)Mbp/Ucd	abnormal urinary bladder morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased lean body mass	J:211773
	female infertility	J:211773
	impaired glucose tolerance	J:211773
	male infertility	J:211773
Nhlh2tm1b(KOMP)Mbp/Nhlh2tm1b(KOMP)Mbp C57BL/6N-Nhlh2tm1b(KOMP)Mbp/Tcp	abnormal bone structure	J:211773
	abnormal cholesterol homeostasis	J:211773
	abnormal epididymis morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal uterus morphology	J:211773
	absent epididymis	J:211773
	absent ovary	J:211773
	absent seminal vesicle	J:211773
	absent testes	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased kidney weight	J:211773
	decreased lean body mass	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	eye hemorrhage	J:211773
	female infertility	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased mean corpuscular volume	J:211773
	increased spleen weight	J:211773
	increased total body fat amount	J:211773
	male infertility	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small uterus	J:211773
Nhlh2tm1Irk/Nhlh2+ involves: 129S4/SvJae * C57BL/6	abnormal motor capabilities/coordination/movement	J:96351
	increased percent body fat/body weight	J:96351
	increased susceptibility to age related obesity	J:96351
	polyphagia	J:96351
Nhlh2tm1Irk/Nhlh2tm1Irk involves: 129S4/SvJae * C57BL/6	abnormal anogenital distance	J:39356
	abnormal estrous cycle	J:101925
	abnormal mating receptivity	J:101925
	abnormal seminal vesicle morphology	J:39356
	abnormal spermatogenesis	J:39356
	abnormal vas deferens morphology	J:39356
	abnormal voluntary movement	J:96351
	absent corpus luteum	J:39356
	azoospermia	J:39356
	bilateral cryptorchism	J:39356
	decreased circulating follicle stimulating hormone level	J:39356
	decreased circulating testosterone level	J:39356
	decreased core body temperature	J:96351
	decreased Leydig cell number	J:39356
	decreased litter size	J:39356
	decreased male germ cell number	J:39356
	decreased superovulation rate	J:101925
	delayed vaginal opening	J:101925
	early reproductive senescence	J:101925
	normal endocrine/exocrine gland phenotype	J:39356
	normal homeostasis/metabolism phenotype	J:39356
	impaired ovarian folliculogenesis	J:39356
	increased percent body fat/body weight	J:96351
	increased susceptibility to age related obesity	J:96351
	male infertility	J:39356
	obese	J:39356
	polyphagia	J:96351
	prolonged diestrus	J:101925
	prolonged proestrus	J:101925
	reduced female fertility	J:39356, J:101925
	reduced male mating frequency	J:39356
	seminiferous tubule degeneration	J:39356
	short estrus	J:101925
	small epididymis	J:39356
	small gonad	J:39356
	small male preputial gland	J:39356
	small ovary	J:39356
	small penis	J:39356
	small seminiferous tubules	J:39356
	small testis	J:39356
	small uterus	J:39356
Nhlh2tm1Thbr/Nhlh2tm1Thbr involves: 129S4/SvJae	abnormal neuron morphology	J:93303
	increased susceptibility to age related obesity	J:93303
	small ovary	J:93303
	small penis	J:93303
	small testis	J:93303
	small uterus	J:93303
Nhlh2tm1Thbr/Nhlh2tm1Thbr Tg(Pomc-EGFP)1Low/0 involves: 129S4/SvJae * C57BL/6J	decreased neuron number	J:199640
	ectopic neuron	J:199640
	increased neuron number	J:199640
Nhlh2tm2Thbr/Nhlh2tm2Thbr Tg(Agrp-cre)1Gsb/0 involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	normal adipose tissue phenotype	J:199640
	normal growth/size/body region phenotype	J:199640
	normal reproductive system phenotype	J:199640
Nhlh2tm2Thbr/Nhlh2tm2Thbr Tg(CMV-cre)1Cgn/0 involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6	decreased circulating estradiol level	J:199640
	decreased neuron number	J:199640
	decreased uterus weight	J:199640
	increased abdominal adipose tissue amount	J:199640
	increased body weight	J:199640
Nhlh2tm2Thbr/Nhlh2tm2Thbr Tg(Gnrh1-cre)1Dlc/0 Tg(Pomc-EGFP)1Low/0 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * CBA	decreased neuron number	J:199640
	normal homeostasis/metabolism phenotype	J:199640
	increased white adipose tissue amount	J:199640
	normal reproductive system phenotype	J:199640
Nhlh2tm2Thbr/Nhlh2tm2Thbr Tg(Pomc-EGFP)1Low/0 Tg(Pomc1-cre)16Lowl/0 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * FVB/N	normal adipose tissue phenotype	J:199640
	normal growth/size/body region phenotype	J:199640
	normal nervous system phenotype	J:199640
	normal reproductive system phenotype	J:199640