101 phenotypes from 11 alleles in 18 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nfkb1Gt(pT1ATGBetageo)1Ruiz/Nfkb1Gt(pT1ATGBetageo)1Ruiz involves: 129S2/SvPas * C57BL/6	no abnormal phenotype detected	J:85162
Nfkb1M1Btlr/Nfkb1+ C57BL/6J-Nfkb1M1Btlr	decreased IgG level	J:216054
	impaired humoral immune response	J:216054
Nfkb1M1Btlr/Nfkb1M1Btlr C57BL/6J-Nfkb1M1Btlr	decreased IgG level	J:216054
	impaired humoral immune response	J:216054
Nfkb1m2Btlr/Nfkb1+ C57BL/6J-Nfkb1m2Btlr	abnormal humoral immune response	J:254822
	decreased central memory CD4-positive, alpha-beta T cell number	J:254822
	decreased effector memory CD4-positive, alpha-beta T cell number	J:254822
	decreased IgM level	J:254822
Nfkb1m2Btlr/Nfkb1m2Btlr C57BL/6J-Nfkb1m2Btlr	abnormal humoral immune response	J:254822
	decreased CD8-positive, naive alpha-beta T cell number	J:254822
	decreased central memory CD4-positive, alpha-beta T cell number	J:254822
	decreased effector memory CD4-positive, alpha-beta T cell number	J:254822
	decreased IgE level	J:254822
	decreased IgG level	J:254822
	decreased IgM level	J:254822
	increased central memory CD8 positive, alpha-beta T cell number	J:254822
Nfkb1M3Btlr/Nfkb1+ C57BL/6J-Nfkb1M3Btlr	abnormal humoral immune response	J:254821
	decreased IgE level	J:254821
	decreased IgG level	J:254821
	increased central memory CD8 positive, alpha-beta T cell number	J:254821
Nfkb1M3Btlr/Nfkb1M3Btlr C57BL/6J-Nfkb1M3Btlr	abnormal humoral immune response	J:254821
	decreased IgE level	J:254821
	decreased IgG level	J:254821
	increased central memory CD8 positive, alpha-beta T cell number	J:254821
	increased susceptibility to induced colitis	J:254821
Nfkb1M4Btlr/Nfkb1M4Btlr C57BL/6J-Nfkb1M4Btlr	decreased B-1 B cell number	J:265169
Nfkb1M5Btlr/Nfkb1M5Btlr C57BL/6J-Nfkb1M5Btlr	decreased B-1a cell number	J:272117
	decreased IgE level	J:272117
	decreased interleukin-1 beta secretion	J:272117
Nfkb1M6Btlr/Nfkb1M6Btlr C57BL/6J-Nfkb1M6Btlr	decreased IgE level	J:272148
Nfkb1tm1a(KOMP)Wtsi/Nfkb1tm1a(KOMP)Wtsi B6JTyr;B6N-Nfkb1tm1a(KOMP)Wtsi/Wtsi	abnormal cornea morphology	J:165965
	abnormal skin condition	J:165965
	decreased circulating amylase level	J:175295
	decreased circulating sodium level	J:165965
	decreased lean body mass	J:175295
	decreased mean corpuscular hemoglobin concentration	J:175295
	decreased thermal nociceptive threshold	J:165965
	increased circulating alkaline phosphatase level	J:165965
	increased circulating free fatty acids level	J:175295
	increased leukocyte cell number	J:165965, J:175295
	increased thermal nociceptive threshold	J:165965
Nfkb1tm1a(KOMP)Wtsi/Nfkb1tm1a(KOMP)Wtsi involves: C57BL/6 * C57BL/6N	decreased IgA level	J:213427
	decreased IgG1 level	J:213427
	decreased NK cell number	J:213427
	decreased regulatory T cell number	J:213427
	decreased respiratory quotient	J:213427
	increased circulating alkaline phosphatase level	J:213427
	increased leukocyte cell number	J:213427
	increased susceptibility to bacterial infection	J:213427
	lymphoid hyperplasia	J:213427
Nfkb1tm1Bal/Nfkb1tm1Bal B6.Cg-Nfkb1tm1Bal/J	abnormal B cell physiology	J:113556
Nfkb1tm1Bal/Nfkb1tm1Bal B6;129P-Nfkb1tm1Bal/J	abnormal calcium ion homeostasis	J:107245
	abnormal CD4-positive, alpha-beta T cell physiology	J:118907
	abnormal cochlear inner hair cell morphology	J:107245
	abnormal cytokine secretion	J:79107
	abnormal dendritic cell physiology	J:118907
	abnormal macrophage physiology	J:118907
	abnormal professional antigen presenting cell physiology	J:118907
	cochlear ganglion degeneration	J:107245
	decreased cochlear nerve compound action potential	J:107245
	decreased susceptibility to autoimmune diabetes	J:118907
	normal homeostasis/metabolism phenotype	J:91366
	normal immune system phenotype	J:118907
	increased apoptosis	J:118907
	increased susceptibility to age-related hearing loss	J:107245
	increased susceptibility to noise-induced hearing loss	J:107245
	normal muscle phenotype	J:135692
Nfkb1tm1Bal/Nfkb1tm1Bal involves: 129P2/OlaHsd	decreased marginal zone B cell number	J:65246
	normal immune system phenotype	J:113514
Nfkb1tm1Bal/Nfkb1tm1Bal involves: 129P2/OlaHsd * C57BL/6	abnormal class switch recombination	J:30268
	abnormal colon morphology	J:67107
	abnormal humoral immune response	J:37184
	abnormal Peyer's patch follicle morphology	J:77049
	abnormal Peyer's patch germinal center morphology	J:77049
	abnormal Peyer's patch T cell area morphology	J:77049
	cecum inflammation	J:67107
	decreased B cell proliferation	J:30268, J:37184
	decreased IgA level	J:37184
	decreased IgE level	J:37184
	decreased IgG1 level	J:37184
	decreased IgM level	J:30268
	decreased immunoglobulin level	J:37184
	decreased interleukin-6 secretion	J:37184
	decreased myeloid dendritic cell number	J:77049
	decreased Peyer's patch number	J:77049
	decreased susceptibility to Picornaviridae infection induced morbidity/mortality	J:37184
	diarrhea	J:67107
	increased susceptibility to bacterial infection	J:37184, J:67107
	increased susceptibility to bacterial infection induced morbidity/mortality	J:37184
	large intestinal inflammation	J:67107
	peritoneal inflammation	J:67107
	premature death	J:37184
	small Peyer's patches	J:77049
Nfkb1tm1Brv/Nfkb1tm1Brv involves: 129S1/Sv	abnormal bone marrow cell morphology/development	J:46912
	abnormal cytokine secretion	J:46912
	abnormal humoral immune response	J:46912
	abnormal inflammatory response	J:46912
	abnormal lymph organ size	J:46912
	abnormal lymphocyte physiology	J:46912
	decreased erythrocyte cell number	J:46912
	decreased IgG3 level	J:46912
	decreased interleukin-2 secretion	J:46912
	decreased interleukin-4 secretion	J:46912
	decreased single-positive T cell number	J:46912
	decreased T cell proliferation	J:46912
	decreased tumor necrosis factor secretion	J:46912
	enlarged lymph nodes	J:46912
	enlarged spleen	J:46912
	extramedullary hematopoiesis	J:46912
	increased B cell proliferation	J:46912
	increased IgE level	J:46912
	increased IgG1 level	J:46912
	increased immunoglobulin level	J:46912
	increased susceptibility to bacterial infection	J:46912
	lethargy	J:46912
	liver inflammation	J:46912
	lung inflammation	J:46912
	myeloid hyperplasia	J:46912
	postnatal growth retardation	J:46912
	premature death	J:46912
	preweaning lethality, incomplete penetrance	J:46912
	rough coat	J:46912
Nfkb1tm1Brv/Nfkb1tm1Brv involves: 129S1/Sv * C57BL/6	decreased osteoclast cell number	J:44112
	normal skeleton phenotype	J:44112
Nfkb1tm1Sley/Nfkb1tm1Sley involves: 129S4/SvJae	decreased tumor necrosis factor secretion	J:196528
Nfkb1tm1Sley/Nfkb1tm1Sley involves: 129S4/SvJae * 129S8/SvEv	abnormal inguinal lymph node morphology	J:142340
	absent inguinal lymph nodes	J:142340
	decreased circulating interleukin-2 level	J:142340
	decreased memory T cell number	J:142340
	decreased regulatory T cell number	J:142340
	decreased T cell proliferation	J:142340
	small inguinal lymph nodes	J:142340
Nfkb1tm1Sley/Nfkb1tm1Sley involves: 129S4/SvJae * 129S8/SvEv * C57BL/6	decreased memory T cell number	J:142340
	decreased NK T cell number	J:142340
	decreased regulatory T cell number	J:142340