Nf2tm1Gth/Nf2+
involves: 129P2/OlaHsd * FVB/N
|
abnormal osteoblast morphology |
J:63264
|
|
abnormal renal tubule morphology |
J:63264
|
|
abnormal tooth development |
J:63264
|
|
increased fibroadenoma incidence |
J:63264
|
|
increased lung adenocarcinoma incidence |
J:63264
|
|
increased mesothelioma incidence |
J:63264
|
|
increased neurofibroma incidence |
J:63264
|
|
increased neurofibrosarcoma incidence |
J:63264
|
|
increased osteoma incidence |
J:63264
|
|
increased osteosarcoma incidence |
J:63264
|
|
increased renal carcinoma incidence |
J:63264
|
|
increased sarcoma incidence |
J:63264
|
|
normal
neoplasm |
J:63264
|
|
normal
nervous system phenotype |
J:63264
|
|
osseous metaplasia |
J:63264
|
Nf2tm1Gth/Nf2tm1Gth
involves: 129P2/OlaHsd * FVB/N
|
embryonic lethality, complete penetrance |
J:63264
|
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)1Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal Schwann cell morphology |
J:63264
|
|
increased hamartoma incidence |
J:63264
|
|
postnatal lethality, complete penetrance |
J:63264
|
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)2Brn/0
involves: 129P2/OlaHsd * FVB/N
|
decreased body size |
J:63264
|
|
decreased body weight |
J:63264
|
|
decreased survivor rate |
J:63264
|
|
delayed tooth eruption |
J:63264
|
|
failure of tooth eruption |
J:63264
|
|
increased susceptibility to otitis media |
J:63264
|
|
premature death |
J:63264
|
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)3Brn/0
involves: 129P2/OlaHsd * FVB/N
|
decreased survivor rate |
J:63264
|
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)4Brn/0
involves: 129P2/OlaHsd * FVB/N
|
decreased survivor rate |
J:63264
|
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)#Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal osteoblast morphology |
J:63264
|
|
abnormal renal tubule morphology |
J:63264
|
|
abnormal Schwann cell morphology |
J:63264
|
|
abnormal tooth development |
J:63264
|
|
decreased survivor rate |
J:63264
|
|
increased mesothelioma incidence |
J:63264
|
|
increased neurofibrosarcoma incidence |
J:63264
|
|
increased odontoma incidence |
J:63264
|
|
increased odontosarcoma incidence |
J:63264
|
|
increased Schwannoma incidence |
J:63264
|
|
osseous metaplasia |
J:63264
|
Nf2tm1Gvn/Nf2tm1Gvn
Not Specified
|
abnormal axon morphology |
J:197562
|
Nf2tm1Tyj/Nf2+
either: (involves: 129S2/SvPas * 129S4/SvJae * C57BL/6) or (involves: 129S2/SvPas * C57BL/6J)
|
increased carcinoma incidence |
J:47282
|
|
increased fibrosarcoma incidence |
J:47282
|
|
increased lung adenocarcinoma incidence |
J:47282
|
|
increased lymphoma incidence |
J:47282
|
|
increased malignant tumor incidence |
J:47282
|
|
increased osteosarcoma incidence |
J:47282
|
|
increased sarcoma incidence |
J:47282
|
|
normal
neoplasm |
J:47282
|
Nf2tm1Tyj/Nf2tm1Tyj
involves: 129S2/SvPas * C57BL/6J
|
abnormal developmental patterning |
J:40596
|
|
abnormal dorsal-ventral axis patterning |
J:40596
|
|
abnormal embryonic tissue morphology |
J:40596
|
|
abnormal extraembryonic tissue morphology |
J:40596
|
|
abnormal placenta morphology |
J:40596
|
|
abnormal visceral endoderm morphology |
J:40596
|
|
absent extraembryonic ectoderm |
J:40596
|
|
absent mesoderm |
J:40596
|
|
disorganized extraembryonic tissue |
J:40596
|
|
embryonic lethality between implantation and somite formation, incomplete penetrance |
J:40596
|
|
failure to gastrulate |
J:40596
|
|
small ectoplacental cone |
J:40596
|
Nf2tm2.1Gth/Nf2+
involves: 129P2/OlaHsd * FVB/N
|
increased fibrosarcoma incidence |
J:63264
|
|
increased lung adenocarcinoma incidence |
J:63264
|
|
increased osteoma incidence |
J:63264
|
|
increased osteosarcoma incidence |
J:63264
|
|
normal
neoplasm |
J:63264
|
|
normal
nervous system phenotype |
J:63264
|
Nf2tm2.1Gth/Nf2tm2.1Gth
involves: 129P2/OlaHsd * FVB/N
|
embryonic lethality, complete penetrance |
J:63264
|
Nf2tm2Gth/Nf2+
Tg(Mpz-cre)#Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal tooth development |
J:63264
|
|
increased fibroadenoma incidence |
J:63264
|
|
increased lung adenocarcinoma incidence |
J:63264
|
|
increased osteoma incidence |
J:63264
|
|
normal
nervous system phenotype |
J:63264
|
Nf2tm2Gth/Nf2tm2Gth
involves: 129P2/OlaHsd
|
abnormal bile duct epithelium morphology |
J:223215
|
|
enlarged liver |
J:132943
|
|
increased tumor incidence |
J:132943
|
Nf2tm2Gth/Nf2tm2Gth
involves: 129P2/OlaHsd * FVB/N
|
increased meningioma incidence |
J:173718
|
Nf2tm2Gth/Nf2tm2Gth
Ptgdstm1.1(cre)Gvn/Ptgds+
involves: 129P2/OlaHsd * FVB/N
|
increased meningioma incidence |
J:173718
|
|
increased osteoma incidence |
J:173718
|
|
increased pituitary adenoma incidence |
J:173718
|
|
normal
mortality/aging |
J:173718
|
Nf2tm2Gth/Nf2tm2Gth
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129P2/OlaHsd * C57BL/6 * DBA
|
abnormal liver morphology |
J:162628
|
|
bile duct hyperplasia |
J:162628
|
|
bile duct proliferation |
J:162628
|
|
enlarged liver |
J:162628
|
|
increased hepatobiliary system tumor incidence |
J:162628
|
|
increased hepatocellular carcinoma incidence |
J:162628
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)1Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal Schwann cell morphology |
J:63264
|
|
decreased body size |
J:63264
|
|
decreased body weight |
J:63264
|
|
decreased survivor rate |
J:63264
|
|
delayed tooth eruption |
J:63264
|
|
failure of tooth eruption |
J:63264
|
|
increased susceptibility to otitis media |
J:63264
|
|
increased tumor incidence |
J:63264
|
|
infertility |
J:63264
|
|
postnatal lethality, incomplete penetrance |
J:63264
|
|
premature death |
J:63264
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)2Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal osteoblast morphology |
J:92413
|
|
abnormal renal tubule morphology |
J:92413
|
|
abnormal Schwann cell morphology |
J:63264,
J:92413
|
|
abnormal tooth development |
J:92413
|
|
cataract |
J:63264,
J:92413
|
|
decreased body size |
J:63264
|
|
decreased body weight |
J:63264
|
|
decreased survivor rate |
J:63264
|
|
increased extremity angiosarcoma incidence |
J:92413
|
|
increased lung adenocarcinoma incidence |
J:92413
|
|
increased neurofibrosarcoma incidence |
J:92413
|
|
increased renal carcinoma incidence |
J:92413
|
|
increased Schwannoma incidence |
J:63264,
J:92413
|
|
increased susceptibility to otitis media |
J:63264
|
|
osseous metaplasia |
J:92413
|
|
postnatal lethality, incomplete penetrance |
J:63264
|
|
premature death |
J:63264
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)3Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal osteoblast morphology |
J:63264
|
|
abnormal renal tubule morphology |
J:63264
|
|
abnormal Schwann cell morphology |
J:63264
|
|
abnormal tooth development |
J:63264
|
|
cataract |
J:63264
|
|
increased fibroadenoma incidence |
J:63264
|
|
increased lung adenocarcinoma incidence |
J:63264
|
|
increased neurofibrosarcoma incidence |
J:63264
|
|
increased odontoma incidence |
J:63264
|
|
increased osteoma incidence |
J:63264
|
|
increased osteosarcoma incidence |
J:63264
|
|
increased renal carcinoma incidence |
J:63264
|
|
increased sarcoma incidence |
J:63264
|
|
increased Schwannoma incidence |
J:63264,
J:92413
|
|
osseous metaplasia |
J:63264
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)4Brn/0
involves: 129P2/OlaHsd * FVB/N
|
decreased survivor rate |
J:63264
|
|
increased Schwannoma incidence |
J:63264
|
|
premature death |
J:63264
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)#Brn/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal osteoblast morphology |
J:63264
|
|
abnormal renal tubule morphology |
J:63264
|
|
abnormal Schwann cell morphology |
J:63264
|
|
abnormal tooth development |
J:63264
|
|
increased neurofibrosarcoma incidence |
J:63264
|
|
increased odontoma incidence |
J:63264
|
|
increased odontosarcoma incidence |
J:63264
|
|
increased osteoma incidence |
J:63264
|
|
increased osteosarcoma incidence |
J:63264
|
|
increased renal carcinoma incidence |
J:63264
|
|
osseous metaplasia |
J:63264
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
increased renal carcinoma incidence |
J:150071
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
|
abnormal lens epithelium morphology |
J:162628
|
|
abnormal lens morphology |
J:162628
|
|
cataract |
J:162628
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Postn-cre)1Sjc/0
involves: 129P2/OlaHsd * FVB/NTac
|
abnormal auditory brainstem response waveform shape |
J:216420
|
|
abnormal spinal nerve morphology |
J:216420
|
|
circling |
J:216420
|
|
enlarged dorsal root ganglion |
J:216420
|
|
head bobbing |
J:216420
|
|
head tilt |
J:216420
|
|
head tossing |
J:216420
|
|
impaired righting response |
J:216420
|
|
impaired swimming |
J:216420
|
|
increased neurofibrosarcoma incidence |
J:216420
|
|
increased or absent threshold for auditory brainstem response |
J:216420
|
|
increased Schwann cell number |
J:216420
|
|
increased Schwannoma incidence |
J:216420
|
|
premature death |
J:216420
|
|
sensorineural hearing loss |
J:216420
|
|
trunk curl |
J:216420
|
Nf2tm2Gth/Nf2tm2Gth
Tg(rx3-icre)1Mjam/0
involves: 129P2/OlaHsd
|
abnormal eye physiology |
J:322987
|
|
abnormal optic cup morphology |
J:322987
|
|
abnormal optic fissure morphology |
J:322987
|
|
cleft palate |
J:322987
|
|
cleft upper lip |
J:322987
|
|
coloboma |
J:322987
|
|
failure of eyelid fusion |
J:322987
|
|
retina pigment epithelium hyperplasia |
J:322987
|
Nf2tm2Gth/Nf2tm2Gth
Tg(TPO-cre)1Shk/0
involves: 129P2/OlaHsd * FVB/NCr
|
abnormal thyroid gland morphology |
J:231492
|
|
normal
neoplasm |
J:231492
|
Nf2tm2Gth/Nf2tm2Gth
Tg(Vil1-cre)20Syr/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
decreased body size |
J:150071
|
|
increased renal carcinoma incidence |
J:150071
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:150071
|
|
perinatal lethality, incomplete penetrance |
J:150071
|
|
postnatal lethality, incomplete penetrance |
J:150071
|
|
premature death |
J:150071
|
Nf2tm2Gvn/Nf2+
Not Specified
|
abnormal axon morphology |
J:197562
|
|
impaired coordination |
J:197562
|
|
increased thermal nociceptive threshold |
J:197562
|
Nf2tm2Gvn/Nf2tm2Gvn
Not Specified
|
abnormal action potential |
J:197562
|
|
abnormal axon morphology |
J:197562
|
|
impaired coordination |
J:197562
|
|
increased thermal nociceptive threshold |
J:197562
|
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