Neu1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Neu1
neuraminidase 1
MGI:97305

29 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Neu1^a/Neu1^a B6.SM-Neu1^a	abnormal enzyme/coenzyme activity	J:147881
Neu1^a/Neu1^a B6.SM-Neu1^a	decreased body weight	J:147881
Neu1^a/Neu1^a SM/J	abnormal enzyme/coenzyme activity	J:43930, J:147881
	abnormal Kupffer cell morphology	J:147881
	abnormal proximal convoluted tubule morphology	J:147881
	decreased body weight	J:147881
Neu1^tm1Adz/Neu1^tm1Adz either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * NMRI)	abnormal choroid plexus morphology	J:76937
	abnormal gait	J:76937
	abnormal Kupffer cell morphology	J:76937
	abnormal lysosome morphology	J:76937
	abnormal microglial cell morphology	J:76937
	abnormal neuron morphology	J:76937
	abnormal urine homeostasis	J:76937
	accumulation of giant lysosomes in kidney/renal tubule cells	J:76937
	decreased body weight	J:76937
	decreased circulating total protein level	J:76937
	distended urinary bladder	J:76937
	edema	J:76937
	enlarged spleen	J:76937
	extramedullary hematopoiesis	J:76937
	extremity edema	J:76937
	eyelid edema	J:76937
	hydronephrosis	J:76937
	hyperkeratosis	J:76937
	ischuria	J:76937
	kyphosis	J:76937
	lordosis	J:76937
	myoclonus	J:76937
	premature death	J:76937
	respiratory distress	J:76937
	skin edema	J:76937
	spleen hyperplasia	J:76937
	tremors	J:76937

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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