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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Myc
myelocytomatosis oncogene
MGI:97250
119 phenotypes from 20 alleles in 24 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hnf4atm1(cre)Sdv/Hnf4a+
Myctm2.1Atp/Myctm2.1Atp
involves: 129P2/OlaHsd * 129S/SvEv
normal liver/biliary system phenotype J:137630
normal mortality/aging J:137630
Mycem1(IMPC)Kmpc/Myc+
C57BL/6NTac-Mycem1(IMPC)Kmpc/Kmpc
abnormal bone structure J:211773
decreased body length J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased fluid intake J:211773
decreased prepulse inhibition J:211773
increased grip strength J:211773
increased startle reflex J:211773
short tibia J:211773
Mycem1(IMPC)Kmpc/Mycem1(IMPC)Kmpc
C57BL/6NTac-Mycem1(IMPC)Kmpc/Kmpc
preweaning lethality, complete penetrance J:211773
Myctm1(Nmyc1)Fwa/Myctm1(Nmyc1)Fwa
involves: 129P2/OlaHsd * C57BL/6
prenatal lethality, complete penetrance J:62573
Myctm1.1(MYC)Gwbk/Myctm1.1(MYC)Gwbk
involves: BALB/cJ * C57BL/6
no abnormal phenotype detected J:189677
Myctm1.1(Nmyc1)Fwa/Myctm1.1(Nmyc1)Fwa
involves: 129P2/OlaHsd * C57BL/6
abnormal skeletal muscle morphology J:62573
cyanosis J:62573
decreased birth body size J:62573
decreased birth weight J:62573
decreased body size J:62573
decreased body weight J:62573
normal immune system phenotype J:62573
neonatal lethality, incomplete penetrance J:62573
Myctm1.1Cksn/Myctm1.1Cksn
B6.129-Myctm1.1Cksn
normal immune system phenotype J:170508
Myctm1.1Dlev/Myctm1.1Dlev
involves: 129S4/SvJae * C57BL/6NCrl
no abnormal phenotype detected J:186832
Myctm1.1Dmlo/Myctm1.1Dmlo
involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
no abnormal phenotype detected J:70610
Myctm1.1Itl/Myctm1.1Itl
involves: 129S6/SvEvTac * C57BL/6NTac
abnormal enterocyte physiology J:188927
abnormal enterocyte proliferation J:188927
abnormal intestinal enteroendocrine cell morphology J:188927
abnormal intestinal goblet cell morphology J:188927
abnormal intestine morphology J:188927
abnormal large intestine crypts of Lieberkuhn morphology J:188927
abnormal response to injury J:188927
abnormal small intestine crypts of Lieberkuhn morphology J:188927
decreased Paneth cell number J:188927
decreased small intestinal villus size J:188927
Myctm1Atp/Myc+
B6.129P2-Myctm1Atp
abnormal NK cell physiology J:132730
decreased memory T cell number J:132730
decreased T cell proliferation J:132730
normal immune system phenotype J:132730
Myctm1Atp/Myc+
involves: 129P2/OlaHsd * FVB/N
decreased body size J:73369
decreased body weight J:73369
decreased bone marrow cell number J:73369
decreased fetal size J:73369
decreased fibroblast proliferation J:73369
decreased T cell proliferation J:73369
decreased white adipose tissue amount J:73369
lymph node hypoplasia J:73369
lymphoid hypoplasia J:73369
postnatal growth retardation J:73369
short tail J:73369
small lymphoid organs J:73369
spleen hypoplasia J:73369
Myctm1Atp/Myctm1Atp
involves: 129P2/OlaHsd
abnormal chorion morphology J:137630
abnormal placenta morphology J:137630
abnormal trophoblast layer morphology J:137630
normal cardiovascular system phenotype J:137630
placental labyrinth hypoplasia J:137630
Myctm1Atp/Myctm1Atp
involves: 129P2/OlaHsd * FVB/N
absent common myeloid progenitor cells J:73369
absent erythroid progenitor cell J:73369
absent fibroblast proliferation J:73369
decreased embryo size J:73369
embryonic lethality during organogenesis, complete penetrance J:73369
pale yolk sac J:73369
Myctm1Atp/Myctm2.1Atp
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
decreased body weight J:73369
decreased bone marrow cell number J:73369
decreased T cell proliferation J:73369
normal immune system phenotype J:73369
lymph node hypoplasia J:73369
spleen hypoplasia J:73369
Myctm1Atp/Myctm2.1Atp
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N * SJL
normal immune system phenotype J:73369
Myctm1Brd/Myc+
involves: 129S7/SvEvBrd * C57BL/6J
decreased litter size J:4556
reduced female fertility J:4556
Myctm1Brd/Myctm1Brd
involves: 129S7/SvEvBrd * C57BL/6J
abnormal embryo turning J:4556
distended pericardium J:4556
embryonic growth retardation J:4556
embryonic lethality during organogenesis, complete penetrance J:4556
enlarged heart J:4556
open neural tube J:4556
Myctm1Jlc/Myctm1Jlc
involves: 129S7/SvEvBrd
abnormal angiogenesis J:79427
abnormal dorsal aorta morphology J:79427
abnormal embryonic erythropoiesis J:79427
abnormal vascular development J:79427
abnormal vasculogenesis J:79427
abnormal visceral yolk sac morphology J:79427
decreased cell proliferation J:79427
decreased common myeloid progenitor cell number J:79427
decreased embryo size J:79427
decreased erythroid progenitor cell number J:79427
decreased tumor incidence J:79427
Myctm1Lbox/Myc+
involves: 129S1/Sv * 129X1/SvJ * FVB/N
enlarged lymph nodes J:97900
enlarged spleen J:97900
increased B cell derived lymphoma incidence J:97900
increased B cell number J:97900
increased spleen weight J:97900
premature death J:97900
Myctm1Lbox/Myctm1Lbox
involves: 129S1/Sv * 129X1/SvJ * FVB/N
decreased T cell number J:97900
enlarged lymph nodes J:97900
enlarged spleen J:97900
increased B cell apoptosis J:97900
increased B cell derived lymphoma incidence J:97900
increased B cell number J:97900
increased B cell proliferation J:97900
increased spleen weight J:97900
premature death J:97900
Myctm1Slek/Myctm1Slek
involves: 129
no abnormal phenotype detected J:131281
Myctm2.1Atp/Myc+
involves: 129P2/OlaHsd * C57BL/6 * SJL
decreased body weight J:73369
decreased T cell proliferation J:73369
Myctm2.1Atp/Myctm2.1Atp
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
abnormal common myeloid progenitor cell morphology J:137630
abnormal proerythroblast morphology J:137630
normal cardiovascular system phenotype J:137630
decreased embryo size J:137630
decreased erythroid progenitor cell number J:137630
embryonic lethality during organogenesis, complete penetrance J:137630
impaired hematopoiesis J:137630
liver hypoplasia J:137630
pale yolk sac J:137630
Myctm2.1Atp/Myctm2.1Atp
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N * SJL
absent fibroblast proliferation J:73369
normal immune system phenotype J:73369
Myctm2.1Atp/Myctm2.1Atp
Tg(Pdx1-cre)1Herr/0
involves: 129P2/OlaHsd * C57BL/6J * CBA/J
abnormal enzyme/coenzyme activity J:146087
abnormal pancreas development J:146087
abnormal pancreas morphology J:146087
abnormal pancreas size J:146087
abnormal pancreatic acinar cell morphology J:146087
abnormal pancreatic acinus morphology J:146087
abnormal pancreatic duct morphology J:146087
absent pancreatic acinar cells J:146087
decreased pancreas weight J:146087
normal endocrine/exocrine gland phenotype J:146087
pancreas hypoplasia J:146087
Myctm2.1Atp/Myctm2.1Atp
Tg(Tek-cre)1Rwng/0
involves: 129P2/OlaHsd * FVB/N
abnormal hematopoietic system morphology/development J:137630
abnormal liver morphology J:137630
normal cardiovascular system phenotype J:137630
embryonic lethality during organogenesis, complete penetrance J:137630
liver hypoplasia J:137630
pale yolk sac J:137630
small liver J:137630
Myctm2Dmlo/Myctm2Dmlo
involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
no abnormal phenotype detected J:70610
Myctm2Fwa/Myc+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6 * CBA
belly spot J:121871
Myctm2Fwa/Myctm2Fwa
involves: 129S6/SvEvTac
no abnormal phenotype detected J:67222
Myctm2Fwa/Myctm2Fwa
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S6/SvEvTac
decreased B cell proliferation J:67222
Myctm2Fwa/Myctm2Fwa
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6 * CBA
abnormal auditory brainstem response J:121871
abnormal frontal bone morphology J:121871
abnormal malleus morphology J:121871
abnormal middle ear ossicle morphology J:121871
abnormal parietal bone morphology J:121871
absent pinna reflex J:121871
conductive hearing impairment J:121871
decreased body size J:121871
decreased body weight J:121871
short malleus manubrium J:121871
short nasal bone J:121871
short snout J:121871
small cranium J:121871
small malleus J:121871
small nasal bone J:121871
variable body spotting J:121871
Myctm3(Tcrb)Fwa/Myc+
involves: 129
abnormal T cell receptor beta chain V(D)J recombination J:131995
Myctm4.1Fwa/Myctm4.1Fwa
involves: 129S6/SvEvTac
induced chromosome breakage J:150339
Myctm37Mnz/Myc+
involves: C57BL/6
induced chromosome breakage J:145691
Myctm39Mnz/Myc+
involves: C57BL/6
spontaneous chromosome breakage J:145691

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory