About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Myb
myeloblastosis oncogene
MGI:97249
32 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Ep300tm1Pkb/Ep300+
Mybtm1Ssp/Myb+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
abnormal megakaryocyte morphology J:98329
decreased thymocyte number J:98329
thrombocytosis J:98329
Lrfn2Tg(CD2-Myb/en)5Kmw/Lrfn2+
involves: C57BL/10 * CBA
abnormal bone marrow cell morphology/development J:125805
abnormal common myeloid progenitor cell morphology J:125805
abnormal lymph node morphology J:125805
decreased T cell number J:126456
decreased T cell proliferation J:126456
Lrfn2Tg(CD2-Myb/en)5Kmw/Lrfn2+
Tg(H2-K-Myc)1Brn/?
involves: C57BL/10 * CBA * FVB/N
abnormal bone marrow cell morphology/development J:125805
abnormal common myeloid progenitor cell morphology J:125805
abnormal erythropoiesis J:125805
abnormal lymph node morphology J:125805
enlarged lymph nodes J:125805
enlarged spleen J:125805
extramedullary hematopoiesis J:125805
lymph node hemorrhage J:125805
lymph node necrosis J:125805
premature death J:125805
spleen hyperplasia J:125805
Lrfn2Tg(CD2-Myb/en)5Kmw/Lrfn2Tg(CD2-Myb/en)5Kmw
involves: C57BL/10 * CBA
abnormal thymus cortex morphology J:126456
abnormal thymus medulla morphology J:126456
decreased CD8-positive, alpha-beta T cell number J:126456
decreased double-negative T cell number J:126456
decreased T cell number J:126456
decreased T cell proliferation J:126456
small spleen J:126456
small thymus J:126456
Mpltm1Wsa/Mpltm1Wsa
MybPlt3/Myb+
involves: 129S1/Sv * C57BL/6
abnormal definitive hematopoiesis J:89601
abnormal megakaryocyte differentiation J:89601
abnormal thrombopoiesis J:89601
thrombocytosis J:89601
Mpltm1Wsa/Mpltm1Wsa
MybPlt3/MybPlt3
involves: 129S1/Sv * C57BL/6
abnormal B cell differentiation J:89601
abnormal definitive hematopoiesis J:89601
abnormal erythropoiesis J:89601
abnormal megakaryocyte differentiation J:89601
abnormal spleen morphology J:89601
abnormal thrombopoiesis J:89601
anemia J:89601
decreased spleen B cell follicle size J:89601
increased spleen red pulp amount J:89601
perinatal lethality, incomplete penetrance J:89601
thrombocytosis J:89601
Mpltm1Wsa/Mpltm1Wsa
MybPlt4/Myb+
involves: 129S1/Sv * C57BL/6
abnormal definitive hematopoiesis J:89601
abnormal megakaryocyte differentiation J:89601
abnormal thrombopoiesis J:89601
thrombocytosis J:89601
Mpltm1Wsa/Mpltm1Wsa
MybPlt4/MybPlt4
involves: 129S1/Sv * C57BL/6
abnormal definitive hematopoiesis J:89601
abnormal erythropoiesis J:89601
abnormal megakaryocyte differentiation J:89601
abnormal spleen morphology J:89601
abnormal thrombopoiesis J:89601
anemia J:89601
decreased leukocyte cell number J:89601
decreased spleen B cell follicle size J:89601
increased spleen red pulp amount J:89601
thrombocytosis J:89601

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory