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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Msx1
msh homeobox 1
MGI:97168
57 phenotypes from 6 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Msx1tm1b(KOMP)Wtsi/Msx1+
C57BL/6N-Msx1tm1b(KOMP)Wtsi/J
decreased thigmotaxis J:211773
increased circulating free fatty acids level J:211773
increased heart weight J:211773
Msx1tm1b(KOMP)Wtsi/Msx1tm1b(KOMP)Wtsi
C57BL/6N-Msx1tm1b(KOMP)Wtsi/J
abnormal facial morphology J:211773
cleft palate J:211773
cyanosis J:211773
preweaning lethality, complete penetrance J:211773
Msx1tm1Bero/Msx1tm1Bero
B6.129P2-Msx1tm1Bero
abnormal brain commissure morphology J:84975
abnormal brain morphology J:84975
abnormal cranium morphology J:42035
abnormal diencephalon morphology J:84975
abnormal palate morphology J:42035
abnormal roof plate morphology J:84975
abnormal subcommissural organ morphology J:84975
absent alveolar process J:42035
absent incisors J:42035
absent malleus processus brevis J:42035
absent molars J:104286
cleft chin J:42035
cleft secondary palate J:42035, J:104286
cyanosis J:42035
dilated fourth ventricle J:84975
dilated third ventricle J:84975
growth retardation of molars J:42035
hydrocephaly J:84975
normal limbs/digits/tail phenotype J:42035
neonatal lethality, complete penetrance J:42035
palatal shelf hypoplasia J:104286
respiratory distress J:42035
short snout J:42035
shortened head J:42035
Msx1tm1Bero/Msx1tm1Bero
involves: 129P2/OlaHsd
increased neuron number J:99936
Msx1tm1Rem/Msx1tm1Rem
Tg(Msx2-cre)5Rem/0
involves: 129S6/SvEvTac * C57BL/6 * SJL
cleft palate J:128624
Msx1tm1Rilm/Msx1tm1Rilm
either: (involves: 129S4/SvJae-Msx1tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129X1/SvJae * C57BL/6J)
abnormal breathing pattern J:17489
abnormal cranium morphology J:17489
abnormal frontal bone morphology J:17489
abnormal mandible morphology J:17489
abnormal metopic suture morphology J:17489
abnormal palatal shelf fusion at midline J:17489
abnormal tooth morphology J:17489
absent alveolar process J:17489
absent gastric milk in neonates J:17489
absent lower incisors J:17489
absent malleus processus brevis J:17489
absent maxillary shelf J:17489
absent palatine bone horizontal plate J:17489
absent premaxilla J:17489
absent upper incisors J:17489
cleft secondary palate J:17489
cyanosis J:17489
growth retardation of molars J:17489
large anterior fontanelle J:17489
neonatal lethality, complete penetrance J:17489
overlapping parietal bones J:17489
short malleus J:17489
short mandible J:17489
short maxilla J:17489
small nasal bone J:17489
Msx1tm1Rilm/Msx1tm1Rilm
involves: 129S4/SvJae
abnormal epitympanic recess morphology J:59750
absent malleus processus brevis J:59750
Msx1tm1Rilm/Msx1tm1Rilm
involves: 129S4/SvJae * BALB/c * CD-1
normal cardiovascular system phenotype J:139946
Msx1tm1Rilm/Msx1tm1Rilm
involves: 129S4/SvJae * CD-1
cleft palate J:311535
Msx1tm2.1(cre/ERT2)Bero/Msx1tm1Bero
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
abnormal embryonic tissue morphology J:194129
abnormal eye morphology J:194129
abnormal facial morphology J:194129
abnormal liver development J:194129
exencephaly J:194129
thoracoabdominoschisis J:194129
Msx1tm3.1Bero/Msx1tm3.1Bero
Not Specified
no abnormal phenotype detected J:208848

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory