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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mmp9
matrix metallopeptidase 9
MGI:97011
97 phenotypes from 5 alleles in 20 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mmp9tm1Amr/Mmp9+
B6.Cg-Mmp9tm1Amr
decreased myocardial infarct size J:102541
Mmp9tm1Amr/Mmp9tm1Amr
B6.Cg-Mmp9tm1Amr
decreased myocardial infarct size J:102541
Mmp9tm1Arnd/Mmp9tm1Arnd
B6.129P2-Mmp9tm1Arnd
decreased histamine level J:110450
increased prostaglandin level J:110450
increased vascular permeability J:110450
Mmp9tm1Arnd/Mmp9tm1Arnd
involves: 129P2/OlaHsd
decreased litter size J:64545
decreased susceptibility to experimental autoimmune encephalomyelitis J:58833
reduced fertility J:64545
Mmp9tm1b(EUCOMM)Wtsi/Mmp9tm1b(EUCOMM)Wtsi
C57BL/6N-Mmp9tm1b(EUCOMM)Wtsi/Ics
short tibia J:211773
Mmp9tm1Itoh/Mmp9tm1Itoh
involves: 129P2/OlaHsd * C57BL/6J
decreased metastatic potential J:55823
Mmp9tm1Tvu/Mmp9tm1Tvu
129S6/SvEvTac-Mmp9tm1Tvu
normal immune system phenotype J:113463
Mmp9tm1Tvu/Mmp9tm1Tvu
B6.129S6-Mmp9tm1Tvu
abnormal tumor morphology J:105098
decreased tumor incidence J:105098
Mmp9tm1Tvu/Mmp9tm1Tvu
C3N.129S6-Mmp9tm1Tvu
decreased susceptibility to bacterial infection J:150311
decreased susceptibility to induced arthritis J:150311
joint inflammation J:150311
joint swelling J:150311
Mmp9tm1Tvu/Mmp9tm1Tvu
either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * CD-1)
abnormal long bone epiphyseal plate morphology J:47297
abnormal long bone hypertrophic chondrocyte zone J:47297
abnormal metatarsal bone morphology J:47297
abnormal trabecular bone morphology J:47297
decreased length of long bones J:47297
delayed bone ossification J:47297
increased width of hypertrophic chondrocyte zone J:47297
osteopetrosis J:47297
short femur J:47297
short tibia J:47297
Mmp9tm1Tvu/Mmp9tm1Tvu
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J)
abnormal angiogenesis J:95880
Mmp9tm1Tvu/Mmp9tm1Tvu
either: FVB.129S6-Mmp9tm1Tvu or (involves: 129S6/SvEvTac)
abnormal response to cardiac infarction J:68211
Mmp9tm1Tvu/Mmp9tm1Tvu
FVB.129S6-Mmp9tm1Tvu
abnormal neutrophil physiology J:104644
abnormal physiological neovascularization J:104786
abnormal response to cardiac infarction J:104786
decreased susceptibility to induced colitis J:104644
decreased susceptibility to xenobiotic induced morbidity/mortality J:104644
normal immune system phenotype J:104644
increased angiogenesis J:104786
increased ventricle muscle contractility J:104786
Mmp9tm1Tvu/Mmp9tm1Tvu
FVB.Cg-Mmp9tm1Tvu/J
abnormal intestinal goblet cell morphology J:128322
abnormal response/metabolism to endogenous compounds J:147593
decreased susceptibility to Flaviviridae infection J:153406
decreased susceptibility to Flaviviridae infection induced morbidity/mortality J:153406
decreased susceptibility to injury J:133660, J:148923
enhanced blood-brain barrier function J:153406
hypoalgesia J:133660
increased body weight J:147593
increased tibialis anterior weight J:147593
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129/Sv * 129S6/SvEvTac
decreased circulating interleukin-10 level J:55723
increased susceptibility to type IV hypersensitivity reaction J:55723
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac
abnormal chemokine level J:84293
abnormal dendritic cell physiology J:84293
abnormal impulse conducting system conduction J:148442
abnormal induced retina neovascularization J:113620
abnormal Langerhans cell physiology J:76157
abnormal myelination J:105765
abnormal myocardial fiber physiology J:148442
abnormal vascular smooth muscle physiology J:109006
abnormal vascular wound healing J:109006
cardiac fibrosis J:148442
decreased cardiac muscle contractility J:148442
decreased dendritic cell number J:84293
decreased IgE level J:84293
decreased inflammatory response J:84293
decreased oligodendrocyte number J:105765
decreased physiological sensitivity to xenobiotic J:84293
decreased susceptibility to induced aneurysm formation J:62760
decreased susceptibility to injury J:79422, J:91478, J:114188
increased circulating interferon-beta level J:148442
increased circulating interferon-gamma level J:148442
increased heart left ventricle posterior wall thickness J:148442
increased susceptibility to dystrophic cardiac calcinosis J:148442
increased susceptibility to Picornaviridae infection J:148442
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:148442
myocarditis J:148442
thick interventricular septum J:148442
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * C57BL/6
abnormal chemokine level J:88065
abnormal cytokine secretion J:88065
abnormal leukocyte morphology J:88065
abnormal response to infection J:126519
decreased interferon-gamma secretion J:88065
increased eosinophil cell number J:88065
increased IgE level J:88065
increased interferon-gamma secretion J:88065
increased interleukin-4 secretion J:88065
increased interleukin-5 secretion J:88065
increased interleukin-13 secretion J:88065
increased lymphocyte cell number J:88065
increased macrophage cell number J:88065
increased monocyte cell number J:88065
increased T cell proliferation J:88065
increased T-helper 2 cell number J:88065
lung inflammation J:88065
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
impaired contextual conditioning behavior J:105763
reduced long-term potentiation J:105763
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * C57BL/6J
abnormal angiogenesis J:101783
abnormal vascular smooth muscle physiology J:101783
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * CD-1
abnormal bone marrow cell physiology J:149957
abnormal hematopoietic stem cell morphology J:149957
abnormal megakaryocyte differentiation J:149957
abnormal retina apoptosis J:129161
decreased susceptibility to injury J:129161
decreased susceptibility to ischemic brain injury J:79535
impaired hematopoiesis J:149957
impaired myelopoiesis J:149957
increased susceptibility to xenobiotic induced morbidity/mortality J:149957
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S6/SvEvTac * FVB/N
decreased neuron apoptosis J:96548
delayed wound healing J:150790

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory