Mmp12 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp12
matrix metallopeptidase 12
MGI:97005

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Itgb6^tm1Des/Itgb6^tm1Des Mmp12^tm1Sds/Mmp12^tm1Sds involves: 129/Sv * 129T2/SvEms	alopecia	J:89578
	lung inflammation	J:89578
	normal respiratory system phenotype	J:89578
Mmp12^tm1Sds/Mmp12^tm1Sds Mmp9^tm1Tvu/Mmp9^tm1Tvu involves: 129S6/SvEvTac * 129X1/SvJ	abnormal myelination	J:105765
	decreased oligodendrocyte number	J:105765
	decreased susceptibility to induced aneurysm formation	J:62760
Mmp12^tm1Sds/Mmp12^tm1Sds Sftpd^tm1Jhf/Sftpd^tm1Jhf involves: 129P2/OlaHsd * 129X1/SvJ * Black Swiss * FVB/N	overexpanded pulmonary alveolus	J:121212
Mmp12^tm1Sds/Mmp12^tm1Sds Timp1^tm1Pds/Timp1^tm1Pds either: (involves: 129S4/SvJae) or (involves: C57BL/6)	decreased susceptibility to bacterial infection	J:94836

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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