Mdk Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mdk
midkine
MGI:96949

26 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mdk^{tm1.1(KOMP)Mbp}/Mdk⁺ C57BL/6N-Mdk^{tm1.1(KOMP)Mbp}/J	increased circulating chloride level	J:211773
Mdk^{tm1.1(KOMP)Mbp}/Mdk⁺ C57BL/6N-Mdk^{tm1.1(KOMP)Mbp}/J	increased circulating sodium level	J:211773
Mdk^{tm1.1(KOMP)Mbp}/Mdk^{tm1.1(KOMP)Mbp} C57BL/6N-Mdk^{tm1.1(KOMP)Mbp}/J	decreased mean corpuscular volume	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased fasting circulating glucose level	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Mdk^tm1Tmu/Mdk^tm1Tmu 129S2-Mdk^tm1Tmu	abnormal dentate gyrus morphology	J:76278
	abnormal hippocampus development	J:60666
	abnormal learning/memory/conditioning	J:76278
	abnormal vascular endothelial cell morphology	J:60666
	increased anxiety-related response	J:76278
	kidney failure	J:93637
	tubular nephritis	J:93637
Mdk^tm1Tmu/Mdk^tm1Tmu B6.129S2-Mdk^tm1Tmu	abnormal circulating enzyme level	J:102069
	abnormal hearing physiology	J:110520
	abnormal macrophage chemotaxis	J:102069
	abnormal social investigation	J:151029
	abnormal wound healing	J:88890
	normal behavior/neurological phenotype	J:151029
	decreased dopamine level	J:151029
	decreased hepatocyte number	J:102069
	decreased liver weight	J:102069
	decreased macrophage cell number	J:102069
	decreased prepulse inhibition	J:151029
	impaired neutrophil chemotaxis	J:102069

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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