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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lipe
lipase, hormone sensitive
MGI:96790
72 phenotypes from 6 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lipetm1b(KOMP)Wtsi/Lipetm1b(KOMP)Wtsi
C57BL/6N-Lipetm1b(KOMP)Wtsi/Ucd
abnormal heart morphology J:211773
enlarged heart J:211773
increased bone mineral density J:211773
increased lean body mass J:211773
male infertility J:211773
Lipetm1Gam/Lipe+
involves: 129S4/SvJae
reduced male fertility J:71782
Lipetm1Gam/Lipetm1Gam
involves: 129S4/SvJae
abnormal epididymis morphology J:71782
abnormal seminiferous tubule epithelium morphology J:71782
abnormal spermatid morphology J:71782
abnormal spermiogenesis J:71782
azoospermia J:71782
decreased male germ cell number J:71782
decreased testis weight J:71782
male infertility J:71782
Lipetm1Gam/Lipetm1Gam
involves: 129S4/SvJae * BALB/c
abnormal abdominal fat pad morphology J:82299
abnormal circulating cholesterol level J:82299
abnormal circulating free fatty acids level J:82299
abnormal fat cell morphology J:82299
decreased circulating leptin level J:82299
decreased liver triglyceride level J:82299
increased brown adipose tissue amount J:82299
increased circulating glucose level J:82299
Lipetm1Ishi/Lipetm1Ishi
B6.129S7-Lipetm1Ishi
abnormal cholesterol homeostasis J:152385
increased circulating cholesterol level J:152385
increased circulating free fatty acid level J:152385
increased circulating glucose level J:152385
increased circulating triglyceride level J:152385
Lipetm1Ishi/Lipetm1Ishi
involves: 129S7/SvEvBrd * C57BL/6
abnormal brown adipose tissue morphology J:59889
abnormal enzyme/coenzyme activity J:59889
abnormal seminiferous tubule epithelium morphology J:59889
abnormal testis morphology J:59889
abnormal white adipose tissue morphology J:59889
abnormal white adipose tissue physiology J:59889
asthenozoospermia J:59889
decreased circulating free fatty acid level J:59889
decreased circulating glycerol level J:59889
normal growth/size/body region phenotype J:59889
increased fat cell size J:59889
increased triglyceride level J:59889
male infertility J:59889
oligozoospermia J:59889
small testis J:59889
Lipetm1Land/Lipetm1Land
involves: 129
abnormal lipid homeostasis J:106148
decreased glycogen level J:106148
Lipetm1Land/Lipetm1Land
involves: 129 * C57BL/6J
abnormal adipose tissue physiology J:85540
abnormal feces composition J:133126
abnormal lipolysis J:85540
abnormal white fat cell morphology J:133126
decreased adiponectin level J:133126
decreased body weight J:133126
decreased circulating leptin level J:133126
decreased muscle cell glucose uptake J:85540
decreased subcutaneous adipose tissue amount J:133126
decreased susceptibility to diet-induced obesity J:133126
decreased white adipose tissue amount J:133126
hyperglycemia J:85540
increased circulating insulin level J:85540
increased food intake J:133126
increased oxygen consumption J:133126
increased pancreatic beta cell mass J:85540
insulin resistance J:85540
male infertility J:85540
oligozoospermia J:85540
pancreatic islet hyperplasia J:85540
Lipetm1Rze/Lipetm1Rze
involves: 129P2/OlaHsd
abnormal glucose homeostasis J:84822
decreased adiponectin level J:84822
decreased circulating free fatty acid level J:84822
decreased circulating insulin level J:84822
decreased circulating triglyceride level J:84822
decreased liver triglyceride level J:84822
increased circulating glucose level J:84822
Lipetm1Rze/Lipetm1Rze
involves: 129P2/OlaHsd * C57BL/6J
abnormal brown adipose tissue physiology J:74644
abnormal fatty acid level J:74644
abnormal lipid level J:74644
abnormal metabolism J:74644
abnormal triglyceride level J:74644
abnormal white adipose tissue physiology J:74644
decreased liver triglyceride level J:74644
decreased triglyceride level J:74644
increased triglyceride level J:74644
Lipetm2Rze/Lipetm2Rze
Tg(Ins2-cre)25Mgn/?
involves: 129 * C57BL/6 * DBA
abnormal glucose homeostasis J:144744
abnormal insulin secretion J:144744
abnormal pancreatic beta cell morphology J:144744
decreased lean body mass J:144744
impaired glucose tolerance J:144744
increased circulating glucose level J:144744
increased circulating leptin level J:144744
increased pancreatic beta cell mass J:144744
increased percent body fat/body weight J:144744

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/16/2019
MGI 6.14
The Jackson Laboratory