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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Krt14
keratin 14
MGI:96688
86 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi
Krt14tm1(cre)Wbm/Krt14+
B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm
abnormal head skin morphology J:253986
abnormal keratinocyte differentiation J:253986
abnormal skin appearance J:253986
abnormal skin physiology J:253986
absent sebaceous gland J:253986
acanthosis J:253986
alopecia J:253986
decreased hair follicle number J:253986
dermatitis J:253986
dry skin J:253986
hyperkeratosis J:253986
parakeratosis J:253986
psoriasis J:253986
scaly skin J:253986
skin lesions J:253986
sparse hair J:253986
thick epidermis J:253986
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Ctnnb1tm1Mmt/Ctnnb1+
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ
increased hair follicle number J:199091
increased salivary gland tumor incidence J:199091
increased squamous cell carcinoma incidence J:199091
premature death J:199091
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S7/SvEvBrd
normal neoplasm J:199091
Cd151tm2Nki/Cd151tm2Nki
Itga3tm1Son/Itga3+
Krt14tm1(cre)Wbm/?
FVB.129P2-Cd151tm2Nki Itga3tm1Son Krt14tm1(cre)Wbm
decreased incidence of tumors by chemical induction J:205736
decreased keratinocyte proliferation J:205736
decreased tumor growth/size J:205736
Cd151tm2Nki/Cd151tm2Nki
Krt14tm1(cre)Wbm/?
FVB.129P2-Cd151tm2Nki Krt14tm1(cre)Wbm
abnormal hair follicle morphology J:205736
decreased incidence of tumors by chemical induction J:205736
decreased keratinocyte proliferation J:205736
decreased tumor growth/size J:205736
increased keratinocyte migration J:205736
thin epidermis J:205736
Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
Tg(Mt1-HGFSF)#Lmb/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
increased incidence of tumors by chemical induction J:240961
increased metastatic potential J:240961
increased tumor growth/size J:240961
Ctnnb1tm1Mmt/Ctnnb1+
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129X1/SvJ
normal neoplasm J:199091
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd
decreased gamma-delta T cell number J:202499
increased neutrophil cell number J:202499
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * C57BL/6
abnormal hair growth J:69463
alopecia J:69463
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * C57BL/6
abnormal hair growth J:69463
alopecia J:69463
Itga3tm1Son/Itga3tm1Son
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * FVB/N
alopecia J:145988
blistering J:145988
enhanced wound healing J:145988
skin inflammation J:145988
thick skin J:145988
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
either: FVB.129-Pard3tm1Shoh Krt14tm1(cre)Wbm or (involves: 129P2/OlaHsd * 129S4/SvJae)
decreased incidence of tumors by chemical induction J:192905
decreased tumor growth/size J:192905
decreased tumor latency J:192905
increased incidence of tumors by chemical induction J:192905
increased metastatic potential J:192905
increased tumor growth/size J:192905
increased tumor latency J:192905
normal neoplasm J:192905
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
abnormal epidermal melanocyte morphology J:240961
abnormal hair follicle melanocyte morphology J:240961
increased incidence of tumors by chemical induction J:240961
increased melanocyte number J:240961
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
Tg(HIST1H2BB/EGFP)1Pa/0
involves: 129 * C57BL/6J
abnormal melanocyte morphology J:240961
Krt14tm1.1(cre)Wbm/Krt14+
Tg(KRT14-Snai1)1Efu/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * CD-1
increased basal cell carcinoma incidence J:229072
increased sebaceous gland tumor incidence J:229072
increased skin squamous cell carcinoma incidence J:229072
increased skin tumor incidence J:229072
Tg(KRT16/KRT14)A2Cou/0
involves: C3H * C57BL/6
no abnormal phenotype detected J:49421
Wlstm1.1Arte/Wlstm1.1Arte
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * C57BL/6
abnormal adipose tissue physiology J:202499
abnormal ear morphology J:202499
abnormal eye morphology J:202499
abnormal hair growth J:202499
abnormal nose morphology J:202499
abnormal skin appearance J:202499
abnormal skin physiology J:202499
abnormal T cell differentiation J:202499
abnormal T cell physiology J:202499
abnormal T cell subpopulation ratio J:202499
decreased body size J:202499
decreased body surface temperature J:202499
decreased double-positive T cell number J:202499
decreased gamma-delta T cell number J:202499
decreased hair follicle number J:202499
decreased T cell number J:202499
decreased thymus weight J:202499
epidermal spongiosis J:202499
flaky skin J:202499
hair follicle degeneration J:202499
impaired skin barrier function J:202499
increased double-negative T cell number J:202499
increased keratinocyte proliferation J:202499
increased macrophage cell number J:202499
increased mast cell number J:202499
increased neutrophil cell number J:202499
increased T cell proliferation J:202499
postnatal growth retardation J:202499
premature death J:202499
reddish skin J:202499
scaly skin J:202499
skin inflammation J:202499
small thymus medulla J:202499
sparse hair J:202499
thin dermal layer J:202499
thin hypodermis J:202499
thin skin J:202499
thymus atrophy J:202499
thymus hypoplasia J:202499
Zbtb17tm1Cksn/Zbtb17tm1.1Cksn
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
rough coat J:123966
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
abnormal coat/ hair morphology J:123966
abnormal epidermal layer morphology J:123966
abnormal hair follicle melanocyte morphology J:123966
abnormal hair follicle morphology J:123966
abnormal hair follicle orientation J:123966
darkened coat color J:123966
decreased curvature of zigzag hairs J:123966
decreased zigzag hair amount J:123966
focal dorsal hair loss J:123966
hyperkeratosis J:123966
increased keratinocyte proliferation J:123966
rough coat J:123966
sparse hair J:123966

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory