Krt14 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Krt14
keratin 14
MGI:96688

22 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Krt14^{tm1(Krt10)Pko}/Krt14^{tm1(Krt10)Pko} B6.Cg-Krt14^{tm1(Krt10)Pko}	abnormal epidermal layer morphology	J:117347
	abnormal epidermis stratum corneum morphology	J:117347
	abnormal keratinocyte apoptosis	J:117347
	increased skin papilloma incidence	J:117347
Krt14^{tm1.1(KOMP)Vlcg}/Krt14⁺ C57BL/6N-Krt14^{tm1.1(KOMP)Vlcg}/Ucd	anophthalmia	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Krt14^{tm1.1(KOMP)Vlcg}/Krt14^{tm1.1(KOMP)Vlcg} C57BL/6N-Krt14^{tm1.1(KOMP)Vlcg}/Ucd	anophthalmia	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Krt14^tm1Der/Krt14⁺ Tg(KRT14-cre/PGR)1Der/? involves: 129X1/SvJ * FVB * ICR	blistering	J:67320
Krt14^tm1Der/Krt14⁺ Tg(KRT5-cre/PGR)1Der/? involves: 129X1/SvJ * FVB * ICR	blistering	J:67320
Krt14^tm1Der/Krt14^tm1Der involves: 129X1/SvJ	abnormal keratinocyte morphology	J:67320
	blistering	J:67320
	postnatal lethality, complete penetrance	J:67320
Krt14^tm1Efu/Krt14^tm1Efu involves: 129	abnormal epidermis stratum basale morphology	J:25763
	abnormal esophagus morphology	J:25763
	abnormal keratinocyte morphology	J:25763
	abnormal trachea morphology	J:25763
	abnormal vagina epithelium morphology	J:25763
	blistering	J:25763
	decreased corneal epithelium thickness	J:25763
	decreased survivor rate	J:25763
	postnatal lethality, incomplete penetrance	J:25763
Krt14^tm2Der/Krt14⁺ involves: 129X1/SvJ	abnormal keratinocyte morphology	J:67320
	blistering	J:67320
	postnatal lethality, complete penetrance	J:67320

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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