38 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itpr1em1Drf/Itpr1+ Not Specified	abnormal iris morphology	J:231957
Itpr1m1Asb/Itpr1m1Asb involves: 129X1/SvJ * C57BL/6	abnormal involuntary movement	J:122793
	premature death	J:122793
Itpr1m1Asb/Itpr1opt involves: 129X1/SvJ * C57BL/6 * C57BLKS	abnormal involuntary movement	J:122793
	premature death	J:122793
Itpr1opt/Itpr1+ B6C3Fe-a/a-Itpr1opt/J	decreased insulin secretion	J:222913
	impaired glucose tolerance	J:222913
Itpr1opt/Itpr1opt involves: C57BLKS	abnormal cell physiology	J:50383
	abnormal locomotor behavior	J:28829, J:37547
	abnormal locomotor coordination	J:50383
	decreased body size	J:28829, J:37547, J:50383
	impaired balance	J:13536
	impaired coordination	J:50383
	impaired righting response	J:13536
	lethality at weaning, complete penetrance	J:13536, J:28829, J:37547
	normal nervous system phenotype	J:13536, J:50383
	opisthotonus	J:13536
	seizures	J:28829, J:37547, J:50383
	weakness	J:50383
Itpr1tm1.1(NCOM)Mfgc/Itpr1+ C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp	small epididymis	J:211773
Itpr1tm1.1(NCOM)Mfgc/Itpr1tm1.1(NCOM)Mfgc C57BL/6N-Itpr1tm1.1(NCOM)Mfgc/Tcp	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Itpr1tm1.1Kmik/Itpr1tm1.1Kmik Tg(Pcp2-cre)2Mpin/0 involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cerebellum morphology	J:199800
	abnormal CNS synaptic transmission	J:199800
	abnormal excitatory postsynaptic potential	J:199800
	abnormal Purkinje cell dendrite morphology	J:199800
	abnormal visual pursuit	J:199800
	absent long-term depression	J:199800
	ataxia	J:199800
	normal behavior/neurological phenotype	J:199800
	decreased Purkinje cell size	J:199800
	normal mortality/aging	J:199800
	normal nervous system phenotype	J:199800
	thin cerebellar molecular layer	J:199800
Itpr1tm1.1Kmik/Itpr1tm1.1Kmik Tg(Pcp2-cre)2Mpin/0 Tg(Pcp2-EGFP)2Yuza/0 involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal Purkinje cell dendrite morphology	J:199800
	normal nervous system phenotype	J:199800
Itpr1tm1Tno/Itpr1tm1Tno involves: 129S4/SvJae * C57BL/6	abnormal excitatory postsynaptic currents	J:30633
	ataxia	J:30633
	decreased brain size	J:30633
	postnatal lethality, incomplete penetrance	J:30633
	prenatal lethality, incomplete penetrance	J:30633
	seizures	J:30633
	tonic-clonic seizures	J:30633