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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
MGI:96617
54 phenotypes from 1 allele in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cd47tm1Fpl/Cd47+
B6.129S7-Cd47tm1Fpl
increased susceptibility to bacterial infection induced morbidity/mortality J:36489
Cd47tm1Fpl/Cd47tm1Fpl
B6.129S7-Cd47tm1Fpl
abnormal neutrophil physiology J:36489
abnormal platelet physiology J:98979
behavioral despair J:162849
decreased osteoclast cell number J:116609
impaired granulocyte bactericidal activity J:36489
impaired neutrophil chemotaxis J:36489
impaired neutrophil phagocytosis J:36489
increased susceptibility to bacterial infection J:36489
increased susceptibility to bacterial infection induced morbidity/mortality J:36489
thrombocytopenia J:98979
Cd47tm1Fpl/Cd47tm1Fpl
C.129S7-Cd47tm1Fpl
abnormal excitatory postsynaptic potential J:59818
abnormal passive avoidance behavior J:59818
abnormal platelet physiology J:98979
decreased osteoclast cell number J:116609
thrombocytopenia J:98979
normal vision/eye phenotype J:107935
Cd47tm1Fpl/Cd47tm1Fpl
involves: 129S7/SvEvBrd
abnormal axon morphology J:116188
abnormal dendrite morphology J:116188
abnormal hindlimb morphology J:133700
abnormal mitochondrial physiology J:133700
abnormal physiological neovascularization J:133700
abnormal skin physiology J:133700
brain ischemia J:148196
decreased T cell number J:36489
impaired neutrophil recruitment J:148196
normal integument phenotype J:133700
Cd47tm1Fpl/Cd47tm1Fpl
involves: 129S7/SvEvBrd * C57BL/6
abnormal bone structure J:147367
abnormal cytokine level J:134866
abnormal muscle fiber morphology J:139652
abnormal osteoclast differentiation J:147367
abnormal skeleton physiology J:147367
abnormal tumor necrosis factor level J:134866
decreased bone resorption J:147367
decreased hematocrit J:134866
decreased hemoglobin content J:134866
decreased leukocyte cell number J:134866
decreased neutrophil cell number J:134866
decreased sensitivity to skin irradiation J:139652
decreased susceptibility to bacterial infection induced morbidity/mortality J:134866
decreased tumor incidence J:147367
increased heart rate J:148948
increased mean systemic arterial blood pressure J:148948
increased susceptibility to bacterial infection J:134866
increased systemic arterial diastolic blood pressure J:148948
increased systemic arterial systolic blood pressure J:148948
increased trabecular bone thickness J:147367
increased trabecular bone volume J:147367
normal muscle phenotype J:139652
normal nervous system phenotype J:204011
pleural effusion J:134866
Cd47tm1Fpl/Cd47tm1Fpl
NOD.129S7-Cd47tm1Fpl
abnormal erythropoiesis J:76580
abnormal spleen morphology J:76580
abnormal splenic cell ratio J:76580
decreased hematocrit J:76580
enlarged spleen J:76580
hemolytic anemia J:76580
increased bone marrow cell number J:76580
premature death J:76580
reticulocytosis J:76580

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory