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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itga3
integrin alpha 3
MGI:96602
35 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cd151tm2Nki/Cd151tm2Nki
Itga3tm1Son/Itga3+
Krt14tm1(cre)Wbm/?
FVB.129P2-Cd151tm2Nki Itga3tm1Son Krt14tm1(cre)Wbm
decreased incidence of tumors by chemical induction J:205736
decreased keratinocyte proliferation J:205736
decreased tumor growth/size J:205736
Itga3tm1Hap/Itga3tm1Hap
Itga6tm2Egl/Itga6tm2Egl
Tg(Mpz-cre)26Mes/0
involves: 129 * C57BL/6 * FVB/NTac
normal nervous system phenotype J:204174
Itga3tm1Hap/Itga3tm1Hap
Tg(CAG-Bgeo/GFP)21Lbe/?
Tg(SFTPC-rtTA)5Jaw/?
Tg(tetO-cre)1Jaw/?
involves: 129 * C57BL/6
abnormal pulmonary alveolus epithelial cell morphology J:144703
Itga3tm1Jak/Itga3+
Itga5tm1Hyn/Itga5+
Itga8tm1Lfr/Itga8+
involves: 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * C57BL/6J
abnormal spatial learning J:84858
reduced long-term potentiation J:84858
Itga3tm1Jak/Itga3+
Itga8tm1Lfr/Itga8+
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J
reduced long-term potentiation J:84858
Itga3tm1Jak/Itga3tm1Jak
Itga6tm1Egl/Itga6tm1Egl
involves: 129S2/SvPas * 129S4/SvJae
abnormal apical ectodermal ridge morphology J:56564
abnormal autopod morphology J:56564
abnormal choroid plexus morphology J:56564
abnormal digit development J:56564
abnormal epidermal layer morphology J:56564
abnormal left lung morphology J:56564
abnormal lens epithelium morphology J:56564
abnormal Mullerian duct morphology J:56564
abnormal neural tube closure J:56564
abnormal primitive urogenital sinus morphology J:56564
abnormal rectum morphology J:56564
abnormal retina nerve fiber layer morphology J:56564
abnormal right lung morphology J:56564
abnormal stratification in cerebral cortex J:56564
abnormal vitreous body morphology J:56564
abnormal Wolffian duct morphology J:56564
absent ureter J:56564
absent urinary bladder J:56564
disorganized retina ganglion layer J:56564
fetal growth retardation J:56564
impaired branching involved in terminal bronchiole morphogenesis J:56564
impaired lung lobe morphogenesis J:56564
lethality throughout fetal growth and development, complete penetrance J:56564
oligodactyly J:56564
pancreas hypoplasia J:56564
pulmonary hypoplasia J:56564
syndactyly J:56564
urethra atresia J:56564

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory