Itga2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga2
integrin alpha 2
MGI:96600

10 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itga2^tm1.1Eck/Itga2⁺ involves: 129P2/OlaHsd	abnormal platelet physiology	J:75683
Itga2^tm1.1Eck/Itga2⁺ involves: 129P2/OlaHsd	decreased platelet aggregation	J:75683
Itga2^tm1.1Eck/Itga2^tm1.1Eck B6.129P2-Itga2^tm1.1Eck	abnormal cell adhesion	J:108931
Itga2^tm1.1Eck/Itga2^tm1.1Eck involves: 129P2/OlaHsd	abnormal platelet aggregation	J:75683
	abnormal platelet physiology	J:75683
	decreased platelet aggregation	J:75683
	normal hematopoietic system phenotype	J:75683
	normal homeostasis/metabolism phenotype	J:75683
Itga2^tm1.1Tkun/Itga2^tm1.1Tkun B6.Cg-Itga2^tm1.1Tkun/J	no abnormal phenotype detected	J:186912
Itga2^tm1.1Tkun/Itga2^tm1.1Tkun Tg(Pf4-icre)Q3Rsko/0 involves: C57BL/6 * SJL	abnormal platelet physiology	J:195799
	decreased mean platelet volume	J:195799
	decreased platelet aggregation	J:195799
Itga2^{tm1b(EUCOMM)Hmgu}/Itga2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Itga2^{tm1b(EUCOMM)Hmgu}/H	tremors	J:211773
Itga2^tm1Eck/Itga2^tm1Eck involves: 129P2/OlaHsd	no abnormal phenotype detected	J:75683
Itga2^tm1Ztr/Itga2^tm1Ztr involves: 129S1/Sv * 129X1/SvJ	abnormal platelet physiology	J:108331
Itga2^tm1Ztr/Itga2^tm1Ztr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal branching of the mammary ductal tree	J:77798
	abnormal cell adhesion	J:77798

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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