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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Il7
interleukin 7
MGI:96561
33 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Il7hlb368/Il7hlb368
C57BL/6J-Il7hlb368/J
abnormal T cell subpopulation ratio J:118450
absent axillary lymph nodes J:118450
absent cervical lymph nodes J:118450
absent mesenteric lymph nodes J:118450
absent Peyer's patches J:118450
absent popliteal lymph nodes J:118450
decreased leukocyte cell number J:82961, J:118450
decreased T cell number J:118450
small inguinal lymph nodes J:118450
small spleen J:118450
small thymus J:118450
spleen hypoplasia J:118450
thymus hypoplasia J:118450
Il7m1Jyen/Il7m1Jyen
involves: C3H * C57BL/6
abnormal myeloid leukocyte morphology J:136470
decreased B cell number J:136470
decreased single-positive T cell number J:136470
lymph node hypoplasia J:136470
spleen hypoplasia J:136470
thymus hypoplasia J:136470
Il7tm1.1Mysl/Il7+
B6.129P2(Cg)-Il7tm1.1Mysl
decreased T cell number J:200544
small lymph nodes J:200544
Il7tm1.1Mysl/Il7tm1.1Mysl
B6.129P2(Cg)-Il7tm1.1Mysl
abnormal mesenteric lymph node morphology J:200544
arrested B cell differentiation J:200544
decreased T cell number J:200544
decreased thymocyte number J:200544
normal immune system phenotype J:200544
small lymph nodes J:200544
thymus hypoplasia J:200544
Il7tm1Dnax/Il7tm1Dnax
involves: 129P2/OlaHsd
decreased thymocyte number J:64861
Il7tm1Dnax/Il7tm1Dnax
involves: 129P2/OlaHsd * C57BL/6
abnormal CD8-positive, alpha beta T cell morphology J:125259
absent lymph nodes J:24165
absent Peyer's patches J:24165
arrested B cell differentiation J:24165
decreased lymphocyte cell number J:24165
decreased spleen weight J:24165
decreased thymus weight J:24165
small spleen J:24165
small thymus J:24165
spleen hypoplasia J:24165
thymus hypoplasia J:24165
Il7tm1Hms/Il7tm1Hms
involves: 129S6/SvEvTac
decreased bone marrow cell number J:43971
spleen hypoplasia J:43971
thymus hypoplasia J:43971
Il7tm2.1Iku/Il7tm2.1Iku
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA
abnormal B cell differentiation J:190615
abnormal NK T cell physiology J:190615
decreased B cell number J:190615
decreased double-negative T cell number J:190615
decreased lymphocyte cell number J:190615
decreased NK T cell number J:190615
decreased T cell number J:190615
normal hematopoietic system phenotype J:190615
normal immune system phenotype J:190615

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory