Il2ra Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il2ra
interleukin 2 receptor, alpha chain
MGI:96549

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdk6^tm2.1Phin/Cdk6^tm2.1Phin Il2ra^tm1Dw/Il2ra^tm1Dw involves: 129S4/SvJae * C57BL/6 * FVB/N	normal hematopoietic system phenotype	J:174697
	increased CD4-positive, alpha-beta T cell number	J:174697
	increased CD8-positive, alpha-beta T cell number	J:174697
	increased hematopoietic stem cell number	J:174697
Fas^lpr/Fas^lpr Il2ra^tm1Dw/Il2ra^tm1Dw Tg(CD2-Ccdc86)1Hfuj/? B6.Cg-Il2ra^tm1Dw Fas^lpr Tg(CD2-Ccdc86)1Hfuj	enlarged spleen	J:151722
Il2ra^tm1Dw/Il2ra^tm1Dw Tg(CD2-Ccdc86)1Hfuj/? B6.Cg-Il2ra^tm1Dw Tg(CD2-Ccdc86)1Hfuj	normal immune system phenotype	J:151722
	increased activated T cell number	J:151722
Il2ra^tm1Dw/Il2ra^tm1Dw Tg(Pgk1-HA)1.1Vbo/? Tg(Tcra/Tcrb)1Vbo/? C.Cg-Il2ra^tm1Dw Tg(Pgk1-HA)1.1Vbo Tg(Tcra/Tcrb)1Vbo	abnormal regulatory T cell physiology	J:112603
	decreased regulatory T cell number	J:112603
	increased regulatory T cell number	J:112603

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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