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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Il1r1
interleukin 1 receptor, type I
MGI:96545
79 phenotypes from 7 alleles in 16 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Il1r1em1(IMPC)Ccpcz/Il1r1em1(IMPC)Ccpcz
C57BL/6NCrl-Il1r1em1(IMPC)Ccpcz/Ccpcz
abnormal freezing behavior J:211773
abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal spleen morphology J:211773
decreased circulating chloride level J:211773
decreased circulating sodium level J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged spleen J:211773
Il1r1em1Qizh/Il1r1em1Qizh
C57BL/6-Il1r1em1Qizh
increased circulating interleukin-6 level J:338375
increased circulating tumor necrosis factor level J:338375
increased susceptibility to induced arthritis J:338375
Il1r1tm1.1Rbl/Il1r1tm1.1Rbl
B6.129(Cg)-Il1r1tm1.1Rbl
no abnormal phenotype detected J:101977
Il1r1tm1.2Quan/Il1r1tm1.2Quan
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:219864
Il1r1tm1Imx/Il1r1tm1Imx
B6.129S7-Il1r1tm1Imx
normal immune system phenotype J:173245
Il1r1tm1Imx/Il1r1tm1Imx
B6.129S7-Il1r1tm1Imx/J
abnormal food intake J:108634
abnormal lean body mass J:108634
abnormal nervous system electrophysiology J:145169
abnormal vascular wound healing J:107324
decreased anxiety-related response J:150445
decreased circulating interleukin-6 level J:125570
decreased circulating interleukin-18 level J:125570
decreased interleukin-6 secretion J:125570, J:148779
decreased locomotor activity J:108634
decreased transforming growth factor beta level J:148779
decreased tumor necrosis factor secretion J:125570
enhanced contextual conditioning behavior J:150445
enhanced wound healing J:148779
impaired glucose tolerance J:108634
increased abdominal fat pad weight J:108634
increased body length J:108634
increased body mass index J:108634
increased body weight J:108634
increased circulating insulin level J:108634
increased circulating insulin-like growth factor I level J:108634
increased circulating interleukin-1 beta level J:125570
increased circulating interleukin-18 level J:125570
increased circulating leptin level J:108634
increased gonadal fat pad weight J:108634
increased growth rate J:108634
increased inguinal fat pad weight J:108634
increased liver weight J:108634
increased mesenteric fat pad weight J:108634
increased percent body fat/body weight J:108634
increased respiratory quotient J:108634
increased retroperitoneal fat pad weight J:108634
increased susceptibility to age related obesity J:108634
increased susceptibility to bacterial infection J:125570
increased susceptibility to bacterial infection induced morbidity/mortality J:125570
increased susceptibility to induced arthritis J:125570
increased total body fat amount J:108634
insulin resistance J:108634
sepsis J:125570
weight loss J:125570
Il1r1tm1Imx/Il1r1tm1Imx
involves: 129 * C57BL/6
decreased circulating interleukin-6 level J:43088
dental pulp necrosis J:58851
increased bone resorption J:58851
increased susceptibility to bacterial infection J:58851
osteomyelitis J:58851
Il1r1tm1Imx/Il1r1tm1Imx
involves: 129S7/SvEvBrd
abnormal neutrophil physiology J:113110
delayed tooth eruption J:103141
Il1r1tm1Imx/Il1r1tm1Imx
involves: 129S7/SvEvBrd * C57BL/6
abnormal neutrophil physiology J:112999
abnormal response/metabolism to endogenous compounds J:112148
decreased blood urea nitrogen level J:112999
decreased circulating creatinine level J:112999
decreased susceptibility to experimental autoimmune uveoretinitis J:115094
decreased susceptibility to kidney reperfusion injury J:112999
increased body weight J:112148
Il1r1tm1Quan/Il1r1tm1Quan
involves: C57BL/6
abnormal inflammatory response J:219864
abnormal microglial cell activation J:219864
Il1r1tm1Quan/Il1r1tm1Quan
Lyz2tm1(cre)Ifo/Lyz2tm1(cre)Ifo
involves: 129P2/OlaHsd * C57BL/6
abnormal inflammatory response J:219864
abnormal microglial cell activation J:219864
Il1r1tm1Quan/Il1r1tm1Quan
Tg(Tek-cre)12Flv/0
involves: C3H * C57BL/6
abnormal inflammatory response J:219864
abnormal microglial cell activation J:219864
Il1r1tm1Roml/Il1r1tm1Roml
C.Cg-Il1r1tm1Roml
decreased eosinophil cell number J:82863
decreased immunoglobulin level J:82863
decreased T cell number J:82863
decreased T cell proliferation J:82863
Il1r1tm1Roml/Il1r1tm1Roml
involves: 129S1/Sv
decreased neutrophil cell number J:193548
decreased susceptibility to induced arthritis J:120707
normal homeostasis/metabolism phenotype J:193548
normal integument phenotype J:126327
Il1r1tm1Roml/Il1r1tm1Roml
involves: 129S1/Sv * BALB/c
decreased incidence of tumors by chemical induction J:191239
impaired neutrophil chemotaxis J:124226
Il1r1tm1Roml/Il1r1tm1Roml
involves: 129S1/Sv * C57BL/6
decreased circulating interleukin-6 level J:42373
decreased circulating serum amyloid protein level J:42373
decreased interleukin-6 secretion J:42373
decreased susceptibility to type IV hypersensitivity reaction J:42373
impaired febrile response J:42373
increased susceptibility to bacterial infection J:42373
Il1r1tm1Roml/Il1r1tm1Roml
NOD.Cg-Il1r1tm1Roml
abnormal cell death J:87251
decreased susceptibility to autoimmune diabetes J:87251

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory