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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Igfbp1
insulin-like growth factor binding protein 1
MGI:96436
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Tg(Afp-IGFBP1)2Csw/Tg(Afp-IGFBP1)2Csw
CBA.Cg-Tg(Afp-IGFBP1)2Csw
decreased birth body size J:108414
decreased body size J:108414
Tg(Afp-IGFBP1)16Csw/Tg(Afp-IGFBP1)16Csw
CBA.Cg-Tg(Afp-IGFBP1)16Csw
decreased body size J:108414
decreased fetal size J:108414
enlarged placenta J:108414
Tg(IGFBP1)2Miel/0
CBACa.Cg-Tg(IGFBP1)2Miel
abnormal decidualization J:78353
abnormal maternal decidual layer morphology J:78353
abnormal placenta junctional zone morphology J:78353
abnormal spongiotrophoblast layer morphology J:78353
decreased embryo weight J:78353
embryonic growth retardation J:78353
increased placenta weight J:78353
increased placental labyrinth size J:78353
prenatal lethality J:78353
Tg(IGFBP1)2Miel/0
involves: C57BL * CBA
abnormal glucose homeostasis J:128964
decreased body weight J:128964
decreased systemic arterial systolic blood pressure J:84652
decreased vasoconstriction J:84652
normal homeostasis/metabolism phenotype J:84652, J:128964
impaired glucose tolerance J:128964
increased circulating glucose level J:128964
increased circulating insulin level J:84652, J:128964

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory