Id3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Id3
inhibitor of DNA binding 3
MGI:96398

48 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Id3^em1(IMPC)Mbp/Id3^em1(IMPC)Mbp C57BL/6N-Id3^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	corneal opacity	J:211773
	decreased body length	J:211773
	decreased brain size	J:211773
	decreased prepulse inhibition	J:211773
	enlarged spleen	J:211773
	increased freezing behavior	J:211773
	increased mean corpuscular volume	J:211773
	increased mean platelet volume	J:211773
	increased red blood cell distribution width	J:211773
	increased spleen weight	J:211773
	increased startle reflex	J:211773
	microphthalmia	J:211773
	persistence of hyaloid vascular system	J:211773
	small kidney	J:211773
	small liver	J:211773
	small testis	J:211773
Id3^tm1Cmu/Id3^tm1Cmu involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal double-positive T cell morphology	J:59969
	abnormal T cell differentiation	J:59969
Id3^tm1Pzg/Id3⁺ involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:159099
Id3^tm1Zhu/Id3^tm1Zhu B6.129S4-Id3^tm1Zhu	decreased salivation	J:93916
Id3^tm1Zhu/Id3^tm1Zhu B6.129S4-Id3^tm1Zhu	decreased tear production	J:93916
Id3^tm1Zhu/Id3^tm1Zhu involves: 129/Sv * C57BL/6	abnormal T cell physiology	J:56950
	decreased B cell proliferation	J:56950
	decreased immunoglobulin level	J:56950
	normal immune system phenotype	J:56950
Id3^tm1Zhu/Id3^tm1Zhu involves: 129S4/SvJaeSor	abnormal eye morphology	J:93916
	abnormal lacrimal gland morphology	J:93916
	decreased salivation	J:93916
	decreased tear production	J:93916
	normal immune system phenotype	J:93916
	increased autoantibody level	J:93916
	lacrimal gland inflammation	J:93916
	normal reproductive system phenotype	J:44278
	salivary gland inflammation	J:93916
Id3^tm1Zhu/Id3^tm1Zhu involves: 129S4/SvJaeSor * C57BL/6	abnormal T cell differentiation	J:144696
Id3^tm2.1Cmu/Id3^tm2.1Cmu Not Specified	decreased thymocyte number	J:176462
	increased B cell number	J:176462
	increased gamma-delta T cell number	J:176462
	increased T follicular helper cell number	J:176462
Id3^tm2.1Zhu/Id3^tm2.1Zhu Tg(Lck-cre)#Zhu/0 involves: 129S6/SvEvTac * C57BL/6 * SJL * SJL/J	abnormal T cell differentiation	J:172701
	decreased CD4-positive, alpha-beta T cell number	J:172701
	decreased CD8-positive, alpha-beta T cell number	J:172701
	decreased salivation	J:172701
	decreased T cell number	J:172701
	increased CD4-positive, alpha-beta memory T cell number	J:172701
	increased CD8-positive, alpha-beta memory T cell number	J:172701
	increased gamma-delta T cell number	J:172701
	parotid gland inflammation	J:172701
	submandibular gland inflammation	J:172701

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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