About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Id3
inhibitor of DNA binding 3
MGI:96398
26 phenotypes from 5 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Id3tm1Cmu/Id3tm1Cmu
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal double-positive T cell morphology J:59969
abnormal T cell differentiation J:59969
Id3tm1Pzg/Id3+
involves: 129S7/SvEvBrd * C57BL/6
no abnormal phenotype detected J:159099
Id3tm1Zhu/Id3tm1Zhu
B6.129S4-Id3tm1Zhu
decreased salivation J:93916
decreased tear production J:93916
Id3tm1Zhu/Id3tm1Zhu
involves: 129/Sv * C57BL/6
abnormal T cell physiology J:56950
decreased B cell proliferation J:56950
decreased immunoglobulin level J:56950
normal immune system phenotype J:56950
Id3tm1Zhu/Id3tm1Zhu
involves: 129S4/SvJaeSor
abnormal eye morphology J:93916
abnormal lacrimal gland morphology J:93916
decreased salivation J:93916
decreased tear production J:93916
normal immune system phenotype J:93916
increased autoantibody level J:93916
lacrimal gland inflammation J:93916
normal reproductive system phenotype J:44278
salivary gland inflammation J:93916
Id3tm1Zhu/Id3tm1Zhu
involves: 129S4/SvJaeSor * C57BL/6
abnormal T cell differentiation J:144696
Id3tm2.1Cmu/Id3tm2.1Cmu
Not Specified
decreased thymocyte number J:176462
increased B cell number J:176462
increased gamma-delta T cell number J:176462
increased T follicular helper cell number J:176462
Id3tm2.1Zhu/Id3tm2.1Zhu
Tg(Lck-cre)#Zhu/0
involves: 129S6/SvEvTac * C57BL/6 * SJL * SJL/J
abnormal T cell differentiation J:172701
decreased CD4-positive, alpha beta T cell number J:172701
decreased CD8-positive, alpha-beta T cell number J:172701
decreased salivation J:172701
decreased T cell number J:172701
increased CD4-positive, alpha-beta memory T cell number J:172701
increased CD8-positive, alpha-beta memory T cell number J:172701
increased gamma-delta T cell number J:172701
parotid gland inflammation J:172701
submandibular gland inflammation J:172701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/05/2019
MGI 6.14
The Jackson Laboratory