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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Id2
inhibitor of DNA binding 2
MGI:96397
49 phenotypes from 7 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Id2tm1Ago/Id2tm1Ago
B6.129-Id2tm1Ago
abnormal cell differentiation J:138276
absent lymph nodes J:116119
absent NK cells J:116119
normal adipose tissue phenotype J:138276
decreased body size J:138276
decreased CD8-positive, alpha-beta T cell number J:116119
decreased inguinal fat pad weight J:138276
decreased interscapular fat pad weight J:138276
decreased white adipose tissue amount J:138276
postnatal lethality, complete penetrance J:138276
Id2tm1Gtbz/Id2tm1Gtbz
involves: C57BL/6
no abnormal phenotype detected J:195908
Id2tm1Mais/Id2tm1Mais
involves: 129X1/SvJ * C57BL/6
abnormal immune system physiology J:146624
abnormal lactation J:146624
decreased lean body mass J:146624
decreased survivor rate J:146624
Id2tm1Mais/Id2tm1Mais
involves: 129X1/SvJ * C57BL/6 * FVB/N
abnormal circadian behavior phase J:146624
arrhythmic circadian behavior persistence J:146624
decreased survivor rate J:146624
hypoactivity J:146624
weight loss J:146624
Id2tm1Mcha/Id2tm1Mcha
involves: C57BL/6 * CD-1
abnormal neuronal precursor proliferation J:143882
abnormal olfaction J:143882
abnormal olfactory bulb morphology J:143882
abnormal rostral migratory stream morphology J:143882
loss of dopaminergic neurons J:143882
normal nervous system phenotype J:143882
premature neuronal precursor differentiation J:143882
small olfactory bulb J:143882
Id2tm1Yyk/Id2tm1Yyk
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * FVB/NJ)
abnormal common lymphocyte progenitor cell morphology J:125739
absent lymph nodes J:125739
absent Peyer's patches J:125739
decreased NK T cell number J:125739
Id2tm1Yyk/Id2tm1Yyk
involves: 129S1/Sv * 129X1/SvJ
abnormal branching of the mammary ductal tree J:96305
abnormal oropharyngeal lymphoid tissue morphology J:78101
absent Peyer's patches J:53267
decreased body size J:96305
decreased lymph node number J:53267
decreased NK cell number J:53267
distended ileum J:53267
distended jejunum J:53267
neonatal lethality, incomplete penetrance J:53267
postnatal growth retardation J:53267
Id2tm1Yyk/Id2tm1Yyk
involves: 129S1/Sv * 129X1/SvJ * NMRI
abnormal lactation J:53267, J:65670
abnormal mammary gland growth during pregnancy J:65670
abnormal oropharyngeal lymphoid tissue morphology J:78101
abnormal ureteropelvic junction morphology J:101195
absent Peyer's patches J:53267
normal behavior/neurological phenotype J:65670
decreased lymph node number J:53267
decreased NK cell number J:53267
distended ileum J:53267
distended jejunum J:53267
hydronephrosis J:101195
ischuria J:101195
postnatal growth retardation J:53267
small inner medullary pyramid J:101195
ureteropelvic junction stenosis J:101195
Id2tm2.1Gtbz/Id2tm2.1Gtbz
Tg(Itgax-cre)1-1Reiz/0
involves: C57BL/6 * CBA
normal hematopoietic system phenotype J:194760
normal immune system phenotype J:194760
Id2tm2b(EUCOMM)Wtsi/Id2+
C57BL/6N-Id2tm2b(EUCOMM)Wtsi/Wtsi
increased blood urea nitrogen level J:211773
increased circulating creatinine level J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory