Hspd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hspd1
heat shock protein 1 (chaperonin)
MGI:96242

38 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hspd1^em1(IMPC)J/Hspd1⁺ C57BL/6NJ-Hspd1^em1(IMPC)J/Mmjax	abnormal coat/hair pigmentation	J:211773
Hspd1^em1(IMPC)J/Hspd1⁺ C57BL/6NJ-Hspd1^em1(IMPC)J/Mmjax	abnormal vocalization	J:211773
Hspd1^em1(IMPC)J/Hspd1^em1(IMPC)J C57BL/6NJ-Hspd1^em1(IMPC)J/Mmjax	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Hspd1^{Gt(OST171441)Lex}/Hspd1⁺ B6.129S5-Hspd1^{Gt(OST171441)Lex}	abnormal corticospinal tract morphology	J:197946
	abnormal mitochondrial ATP synthesis coupled electron transport	J:197946
	abnormal mitochondrial morphology	J:197946
	abnormal motor neuron morphology	J:197946
	abnormal voluntary movement	J:197946
	decreased skeletal muscle fiber size	J:197946
	disorganized mitochondrial cristae	J:197946
	impaired coordination	J:197946
	limb grasping	J:197946
	spasticity	J:197946
Hspd1^{Gt(OST171441)Lex}/Hspd1⁺ involves: 129S5/SvEvBrd * C57BL/6J	transmission ratio distortion	J:171183
Hspd1^{Gt(OST171441)Lex}/Hspd1^{Gt(OST171441)Lex} involves: 129S5/SvEvBrd * C57BL/6J	decreased embryo size	J:171183
	embryonic growth retardation	J:171183
	embryonic lethality between implantation and placentation, incomplete penetrance	J:171183
	embryonic lethality during organogenesis, complete penetrance	J:171183
Hspd1^{tm1c(EUCOMM)Hmgu}/Hspd1^{tm1c(EUCOMM)Hmgu} A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/A1cf⁺ involves: Black Swiss C57BL/6 * C57BL/6N * FVB/N	abnormal cardiovascular system physiology	J:283049
	abnormal heart echocardiography feature	J:283049
	abnormal heart ventricles weight	J:283049
	abnormal mitochondrial physiology	J:283049
	cardiac fibrosis	J:283049
	congestive heart failure	J:283049
	decreased ventricle muscle contractility	J:283049
	dilated cardiomyopathy	J:283049
	dilated heart ventricle	J:283049
	enlarged heart	J:283049
	increased lung weight	J:283049
	oxidative stress	J:283049
	premature death	J:283049
	thin ventricular wall	J:283049
Hspd1^{tm1c(EUCOMM)Hmgu}/Hspd1^{tm1c(EUCOMM)Hmgu} Tg(Tek-cre)12Flv/0 involves: Black Swiss * C3H * C57BL/6 * C57BL/6N	abnormal blood cell morphology	J:282096
	abnormal blood vessel morphology	J:282096
	abnormal erythrocyte physiology	J:282096
	anemia	J:282096
	decreased erythrocyte cell number	J:282096
	embryonic growth retardation	J:282096
	embryonic lethality during organogenesis, complete penetrance	J:282096

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