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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hspa5
heat shock protein 5
MGI:95835
58 phenotypes from 5 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hspa5baffled/Hspa5baffled
FVB.Cg-Hspa5baffled
abnormal axon extension J:191772
abnormal axon fasciculation J:191772
abnormal axon morphology J:191772
abnormal brain internal capsule morphology J:191772
abnormal brain white matter morphology J:191772
abnormal cerebellum morphology J:191772
abnormal cerebral cortex morphology J:191772
abnormal corpus callosum morphology J:191772
abnormal cortical intermediate zone morphology J:191772
abnormal neuron differentiation J:191772
abnormal neuron proliferation J:191772
abnormal stratification in cerebral cortex J:191772
decreased body size J:191772
decreased surfactant secretion J:191772
forebrain hypoplasia J:191772
neonatal lethality, complete penetrance J:191772
normal nervous system phenotype J:191772
respiratory failure J:191772
Hspa5baffled/Hspa5baffled
Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N
abnormal axon extension J:168258
abnormal axon fasciculation J:168258
abnormal cerebral cortex morphology J:168258
abnormal cortical intermediate zone morphology J:168258
abnormal hippocampus morphology J:168258
abnormal telencephalon morphology J:168258
cleft palate J:168258
hematoma J:168258
neonatal lethality, complete penetrance J:168258
respiratory distress J:168258
small kidney J:168258
small olfactory bulb J:168258
Hspa5tm1.1(KOMP)Vlcg/Hspa5+
C57BL/6N-Hspa5tm1.1(KOMP)Vlcg/J
decreased circulating insulin level J:211773
decreased lean body mass J:211773
decreased total body fat amount J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
increased lean body mass J:211773
increased or absent threshold for auditory brainstem response J:211773
increased total body fat amount J:211773
Hspa5tm1.1(KOMP)Vlcg/Hspa5tm1.1(KOMP)Vlcg
C57BL/6N-Hspa5tm1.1(KOMP)Vlcg/J
embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Hspa5tm1.1Alee/Hspa5tm1.1Alee
involves: 129 * C57BL/6 * FVB/N
abnormal blastocyst morphology J:111416
abnormal inner cell mass apoptosis J:111416
absent inner cell mass proliferation J:111416
embryonic lethality at implantation, complete penetrance J:111416
empty decidua capsularis J:111416
failure of blastocyst to hatch from the zona pellucida J:111416
Hspa5tm1Alee/Hspa5tm1Alee
involves: 129 * C57BL/6
no abnormal phenotype detected J:111416
Hspa5tm1Alee/Hspa5tm1Alee
Tg(Pbsn-cre)4Prb/0
involves: 129 * C57BL/6 * DBA/2
normal reproductive system phenotype J:142106
Hspa5tm1Aoe/Hspa5+
B6.129-Hspa5tm1Aoe
abnormal renal tubule morphology J:130961
dilated renal tubules J:130961
increased susceptibility to injury J:130961
renal interstitial fibrosis J:130961
renal tubule atrophy J:130961
Hspa5tm1Aoe/Hspa5tm1Aoe
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal alveolar lamellar body morphology J:131209
abnormal pulmonary alveolus epithelial cell morphology J:131209
abnormal surfactant secretion J:131209
abnormal type II pneumocyte morphology J:131209
atelectasis J:131209
cyanosis J:131209
decreased fetal size J:131209
neonatal lethality, complete penetrance J:131209
pallor J:131209
pulmonary alveolar hemorrhage J:131209
respiratory distress J:131209

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory